Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Hilmar, Lemke"'
Autor:
Hilmar Lemke
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Antigen determinants (epitopes) are recognized by the combining sites (paratopes) of B and T cell antigen receptors (BCR/TCR), which again express clone-specific epitopes (idiotopes) that can be recognized by BCR/TCR not only of genetically different
Externí odkaz:
https://doaj.org/article/fc4362893bb64ffda1112a31ccff0090
Autor:
Hilmar Lemke
Publikováno v:
Science (New York, N.Y.). 355(6326)
The investigation on the epidemiology of all known human influenza cases worldwide by K. M. Gostic et al. (“Potent protection against H5N1 and H7N9 influenza via childhood hemagglutinin imprinting,” Research Article, 11 November 2016, p. [722][1]
Autor:
Hilmar Lemke
Publikováno v:
Critical reviews in immunology. 36(1)
The clone-specific or idiotypic characters of B as well as T cell antigen receptors (BCRs/TCRs) are associated with (1) the third-complementarity-determining regions (CDR3s) that are created during V(D)J recombination (they scarcely occur in antibody
Autor:
Joachim Grötzinger, Hinrich P. Hansen, Stefan Rose-John, Katja Klausz, Hilmar Lemke, Mohammad Shomali, Inken Lorenzen, Matthias Peipp, Ahmad Trad, Andre Mauermann, Nina Hedemann, Kosuke Yamamoto, Christine Desel
Publikováno v:
Cancer Immunology, Immunotherapy. 62:411-421
A disintegrin and metalloproteinase 17 (ADAM17) is significantly upregulated not only in malignant cells but also in the pro-inflammatory microenvironment of breast cancer. There, ADAM17 is critically involved in the processing of tumor-promoting pro
Publikováno v:
Biocontrol Science and Technology. 17:295-302
Quality control of Bacillus thuringiensis ssp. israelensis (Bti) products is currently based on international toxic units (ITUs). The potency of products is related to the activity of a standard (IPS-82, Institute Pasteur, Paris) assessed in bioassay
Publikováno v:
Trends in Immunology. 25:180-186
Maternal antibodies provide offspring with passive immunity and exert various active immunostimulatory functions, such as (i) antimicrobial protection through non-antigen-reactive antibodies, namely anti-idiotypes, (ii) allergen-specific suppression
Publikováno v:
Journal of Biological Chemistry. 278:23301-23310
Trypanosomes express an enzyme called trans-sialidase (TS), which enables the parasites to transfer sialic acids from the environment onto trypanosomal surface molecules. Here we describe the purification and characterization of two TS forms from the
Autor:
Enno Christophers, Michael Weichenthal, Hinrich P. Hansen, Regina Fölster-Holst, Hilmar Lemke, Jörg Wehde, Tilo Henseler
Publikováno v:
Acta Dermato-Venereologica. 82:245-248
The levels of soluble CD30 in 79 patients with atopic Elevated plasma levels of soluble CD30 (sCD30) have been found in patients with AD but not in those with dermatitis were compared with those found in 54 patients with psoriasis and 36 control indi
Publikováno v:
FEBS Letters. 452:351-354
A new phagemid cloning vector for positive selection of recombinants, pBa-7, was constructed which contains an active barnase gene encoding the cytotoxic ribonuclease from Bacillus amyloliquefaciens, under control of the lac promoter. PBa-7 is a deri
Autor:
Volker Diehl, Hinrich P. Hansen, A. Klimka, R C Roovers, Jan-Willem Arends, Andreas Engert, Hennie R. Hoogenboom, B. Matthey, Stefan Barth, Hilmar Lemke
Publikováno v:
British Journal of Cancer
The human CD30 receptor is highly overexpressed on the surface of Hodgkin Reed-Sternberg cells and has been shown to be an excellent target for selective immunotherapy using monoclonal antibody-based agents such as immunotoxins. To construct a new re