Helminth infection induces a distinct subset of CD101 ^hi lung tissue-infiltrating eosinophils that are differentially regulated by type 2 cytokines.

Autor: Noble SL; Malaghan Institute of Medical Research, Wellington, New Zealand.; Department of Medicine, University of Otago, Wellington, New Zealand., Vacca F; Malaghan Institute of Medical Research, Wellington, New Zealand., Hilligan KL; Malaghan Institute of Medical Research, Wellington, New Zealand., Mules TC; Malaghan Institute of Medical Research, Wellington, New Zealand.; Department of Medicine, University of Otago, Wellington, New Zealand.; Te Whatu Ora, Capital Coast and Hutt Valley, Wellington, New Zealand., Le Gros G; Malaghan Institute of Medical Research, Wellington, New Zealand., Inns S; Department of Medicine, University of Otago, Wellington, New Zealand.; Te Whatu Ora, Capital Coast and Hutt Valley, Wellington, New Zealand.

Publikováno v: Immunology and cell biology [Immunol Cell Biol] 2024 Sep; Vol. 102 (8), pp. 734-746. Date of Electronic Publication: 2024 Jun 26.

BACH1 promotes tissue necrosis and Mycobacterium tuberculosis susceptibility.

Autor: Amaral EP; Immunobiology Section, Laboratory of Parasitic Diseases, NIAID, NIH, Bethesda, MD, USA. eduardo.amaral@nih.gov., Namasivayam S; Immunobiology Section, Laboratory of Parasitic Diseases, NIAID, NIH, Bethesda, MD, USA., Queiroz ATL; Laboratório de Inflamação e Biomarcadores, Instituto Gonçalo Moniz, Fundação Oswaldo Cruz (FIOCRUZ), Salvador, Bahia, Brazil., Fukutani E; Laboratório de Inflamação e Biomarcadores, Instituto Gonçalo Moniz, Fundação Oswaldo Cruz (FIOCRUZ), Salvador, Bahia, Brazil., Hilligan KL; Immunobiology Section, Laboratory of Parasitic Diseases, NIAID, NIH, Bethesda, MD, USA., Aberman K; Immunobiology Section, Laboratory of Parasitic Diseases, NIAID, NIH, Bethesda, MD, USA., Fisher L; Immunobiology Section, Laboratory of Parasitic Diseases, NIAID, NIH, Bethesda, MD, USA.; Immunology and Microbial Pathogenesis Program, Weill Cornell Medicine Graduate School of Medical Sciences, New York, NY, USA., Bomfim CCB; Immunobiology Section, Laboratory of Parasitic Diseases, NIAID, NIH, Bethesda, MD, USA., Kauffman K; T lymphocyte Biology Section, Laboratory of Parasitic Diseases, National Institutes of Allergy and Infectious Disease, National Institutes of Health, Bethesda, MD, USA., Buchanan J; T lymphocyte Biology Section, Laboratory of Parasitic Diseases, National Institutes of Allergy and Infectious Disease, National Institutes of Health, Bethesda, MD, USA., Santuo L; T lymphocyte Biology Section, Laboratory of Parasitic Diseases, National Institutes of Allergy and Infectious Disease, National Institutes of Health, Bethesda, MD, USA., Gazzinelli-Guimaraes PH; Helminth Immunology Section, Laboratory of Parasitic Diseases, National Institutes of Allergy and Infectious Disease, National Institutes of Health, Bethesda, MD, USA., Costa DL; Immunobiology Section, Laboratory of Parasitic Diseases, NIAID, NIH, Bethesda, MD, USA.; Departmento de Bioquímica e Imunologia, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, Brazil.; Programa de Pós-Graduação em Imunologia Básica e Aplicada, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, Brazil., Teixeira MA; Multinational Organization Network Sponsoring Translational and Epidemiological Research (MONSTER) Initiative, Salvador, Brazil., Barreto-Duarte B; Laboratório de Inflamação e Biomarcadores, Instituto Gonçalo Moniz, Fundação Oswaldo Cruz (FIOCRUZ), Salvador, Bahia, Brazil.; Multinational Organization Network Sponsoring Translational and Epidemiological Research (MONSTER) Initiative, Salvador, Brazil.; Curso de Medicina, Universidade Salvador (UNIFACS), Laureate Universities, Salvador, Bahia, Brazil., Rocha CG; Department of Pathology, School of Medicine of the Federal University of Bahia, Salvador, Bahia, Brazil.; Center for Biotechnology and Cell Therapy, D'Or Institute for Research and Education (IDOR), Sao Rafael Hospital, Salvador, Bahia, Brazil., Santana MF; Departmento de Ensino e Pesquisa, Fundação Centro de Controle de Oncologia do Estado do Amazonas-FCECON, Manaus, Amazonas, Brazil.; Fundação Medicina Tropical Doutor Heitor Vieira Dourado, Manaus, Amazonas, Brazil.; Programa de Pós-Graduação em Medicina Tropical, Universidade do Estado do Amazonas, Manaus, Amazonas, Brazil., Cordeiro-Santos M; Fundação Medicina Tropical Doutor Heitor Vieira Dourado, Manaus, Amazonas, Brazil.; Programa de Pós-Graduação em Medicina Tropical, Universidade do Estado do Amazonas, Manaus, Amazonas, Brazil.; Faculdade de Medicina, Universidade Nilton Lins, Manaus, Amazonas, Brazil., Barber DL; T lymphocyte Biology Section, Laboratory of Parasitic Diseases, National Institutes of Allergy and Infectious Disease, National Institutes of Health, Bethesda, MD, USA., Wilkinson RJ; Wellcome Centre for Infectious Disease Research in Africa, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Cape Town, South Africa.; The Francis Crick Institute, London, UK.; Department of Infectious Disease, Imperial College London, London, UK., Kramnik I; Boston University School of Medicine, Boston, MA, USA., Igarashi K; Department of Biochemistry, Tohoku University Graduate School of Medicine, Sendai, Japan., Scriba T; South African Tuberculosis Vaccine Initiative, Institute of Infectious Disease and Molecular Medicine and Division of Immunology, Department of Pathology, University of Cape Town, Observatory, South Africa., Mayer-Barber KD; Inflammation and Innate Immunity Unit, Laboratory of Clinical Immunology and Microbiology, NIAID, NIH, Bethesda, MD, USA., Andrade BB; Laboratório de Inflamação e Biomarcadores, Instituto Gonçalo Moniz, Fundação Oswaldo Cruz (FIOCRUZ), Salvador, Bahia, Brazil.; Multinational Organization Network Sponsoring Translational and Epidemiological Research (MONSTER) Initiative, Salvador, Brazil.; Curso de Medicina, Universidade Salvador (UNIFACS), Laureate Universities, Salvador, Bahia, Brazil.; Department of Pathology, School of Medicine of the Federal University of Bahia, Salvador, Bahia, Brazil.; Curso de Medicina, Escola Bahiana de Medicina e Saúde Pública, Salvador, Bahia, Brazil.; Faculdade de Medicina, Universidade Federal da Bahia, Salvador, Bahia, Brazil.; Curso de Medicina, Universidade Faculdade de Tecnologia e Ciências (UniFTC), Salvador, Bahia, Brazil.; Division of Infectious Diseases, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN, USA., Sher A; Immunobiology Section, Laboratory of Parasitic Diseases, NIAID, NIH, Bethesda, MD, USA. asher@niaid.nih.gov.

Publikováno v: Nature microbiology [Nat Microbiol] 2024 Jan; Vol. 9 (1), pp. 120-135. Date of Electronic Publication: 2023 Dec 08.

Endogenous and Therapeutic 25-Hydroxycholesterols May Worsen Early SARS-CoV-2 Pathogenesis in Mice.

Autor: Fessler MB; Immunity, Inflammation and Disease Laboratory., Madenspacher JH; Immunity, Inflammation and Disease Laboratory., Baker PJ; Inflammation and Innate Immunity Unit., Hilligan KL; Immunobiology Section, and., Bohrer AC; Inflammation and Innate Immunity Unit., Castro E; Inflammation and Innate Immunity Unit., Meacham J; Immunity, Inflammation and Disease Laboratory., Chen SH; Viral Vector Core Facility, Neurobiology Laboratory., Johnson RF; SARS-CoV-2 Virology Core, Laboratory of Viral Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland., McDonald JG; Department of Molecular Genetics and.; Center for Human Nutrition, University of Texas Southwestern Medical Center, Dallas, Texas; and., Martin NP; Viral Vector Core Facility, Neurobiology Laboratory., Tucker CJ; Fluorescence Microscopy and Imaging Center, Signal Transduction Laboratory, and., Mahapatra D; Integrated Laboratory Systems, LLC, Research Triangle Park, North Carolina., Cesta M; Division of the National Toxicology Program, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina., Mayer-Barber KD; Inflammation and Innate Immunity Unit.

Publikováno v: American journal of respiratory cell and molecular biology [Am J Respir Cell Mol Biol] 2023 Dec; Vol. 69 (6), pp. 638-648.

Co-infection of mice with SARS-CoV-2 and Mycobacterium tuberculosis limits early viral replication but does not affect mycobacterial loads.

Autor: Baker PJ; Inflammation and Innate Immunity Unit, Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD, United States., Amaral EP; Inflammation and Innate Immunity Unit, Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD, United States., Castro E; Inflammation and Innate Immunity Unit, Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD, United States., Bohrer AC; Inflammation and Innate Immunity Unit, Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD, United States., Torres-Juárez F; Inflammation and Innate Immunity Unit, Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD, United States., Jordan CM; Inflammation and Innate Immunity Unit, Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD, United States., Nelson CE; T Lymphocyte Biology Section, Laboratory of Parasitic Diseases, NIAID, NIH, Bethesda, MD, United States., Barber DL; T Lymphocyte Biology Section, Laboratory of Parasitic Diseases, NIAID, NIH, Bethesda, MD, United States., Johnson RF; SARS-CoV-2 Virology Core, Laboratory of Viral Diseases, NIAID, NIH, Bethesda, MD, United States., Hilligan KL; Immunobiology Section, Laboratory of Parasitic Diseases, NIAID, NIH, Bethesda, MD, United States., Mayer-Barber KD; Inflammation and Innate Immunity Unit, Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD, United States.

Publikováno v: Frontiers in immunology [Front Immunol] 2023 Sep 01; Vol. 14, pp. 1240419. Date of Electronic Publication: 2023 Sep 01 (Print Publication: 2023).

Incorporation of SARS-CoV-2 spike NTD to RBD protein vaccine improves immunity against viral variants.

Autor: Montgomerie I; School of Biological Sciences, Victoria University of Wellington, Wellington, New Zealand., Bird TW; School of Biological Sciences, Victoria University of Wellington, Wellington, New Zealand., Palmer OR; Malaghan Institute of Medical Research, Wellington, New Zealand., Mason NC; Malaghan Institute of Medical Research, Wellington, New Zealand., Pankhurst TE; Malaghan Institute of Medical Research, Wellington, New Zealand., Lawley B; Department of Microbiology and Immunology, School of Biomedical Sciences, University of Otago, Dunedin, New Zealand., Hernández LC; Department of Microbiology and Immunology, School of Biomedical Sciences, University of Otago, Dunedin, New Zealand., Harfoot R; Department of Microbiology and Immunology, School of Biomedical Sciences, University of Otago, Dunedin, New Zealand., Authier-Hall A; Malaghan Institute of Medical Research, Wellington, New Zealand., Anderson DE; Department of Microbiology and Immunology, University of Melbourne, at The Peter Doherty Institute for Infection and Immunity, Melbourne, VIC, Australia., Hilligan KL; Malaghan Institute of Medical Research, Wellington, New Zealand.; Laboratory of Parasitic Diseases, National Institutes of Health, Bethesda, MD, USA., Buick KH; Malaghan Institute of Medical Research, Wellington, New Zealand., Mbenza NM; School of Biological Sciences, Victoria University of Wellington, Wellington, New Zealand., Mittelstädt G; Ferrier Research Institute, Victoria University of Wellington, Wellington, New Zealand., Maxwell S; School of Biological Sciences, Victoria University of Wellington, Wellington, New Zealand., Sinha S; Department of Microbiology and Immunology, School of Biomedical Sciences, University of Otago, Dunedin, New Zealand., Kuang J; Department of Microbiology and Immunology, School of Biomedical Sciences, University of Otago, Dunedin, New Zealand., Subbarao K; Department of Microbiology and Immunology, University of Melbourne, at The Peter Doherty Institute for Infection and Immunity, Melbourne, VIC, Australia.; WHO Collaborating Centre for Reference and Research on Influenza, Melbourne, VIC, Australia., Parker EJ; Ferrier Research Institute, Victoria University of Wellington, Wellington, New Zealand., Sher A; Laboratory of Parasitic Diseases, National Institutes of Health, Bethesda, MD, USA., Hermans IF; Malaghan Institute of Medical Research, Wellington, New Zealand., Ussher JE; Department of Microbiology and Immunology, School of Biomedical Sciences, University of Otago, Dunedin, New Zealand., Quiñones-Mateu ME; Department of Microbiology and Immunology, School of Biomedical Sciences, University of Otago, Dunedin, New Zealand.; Webster Centre for Infectious Diseases, University of Otago, Dunedin, New Zealand., Comoletti D; School of Biological Sciences, Victoria University of Wellington, Wellington, New Zealand., Connor LM; School of Biological Sciences, Victoria University of Wellington, Wellington, New Zealand.; Malaghan Institute of Medical Research, Wellington, New Zealand.

Publikováno v: IScience [iScience] 2023 Apr 21; Vol. 26 (4), pp. 106256. Date of Electronic Publication: 2023 Feb 20.