Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Hillary Stires"'
Autor:
Hillary Stires, Igor Bado, Thelma Brown, Martha Carlson, Isaac S. Chan, Gloria V. Echeverria, Andrew J. Ewald, Bora Lim, Carla Lloyd, Julia Maues, Steffi Oesterreich, Robert N. Riter, Kelly Shanahan, Alana L. Welm, Josh Newby
Publikováno v:
npj Breast Cancer, Vol 8, Iss 1, Pp 1-5 (2022)
Abstract Including patient advocates in basic cancer research ensures that breast cancer research is intentional, supports effective communication with broader audiences, and directly connects researchers with those who they are striving to help. Des
Externí odkaz:
https://doaj.org/article/f2333b9b76f7493082dff1a374d8ec46
Publikováno v:
PLoS ONE, Vol 18, Iss 1, p e0267492 (2023)
Matriptase is a type II transmembrane serine protease that is widely expressed in normal epithelial cells and epithelial cancers. Studies have shown that regulation of matriptase expression and activation becomes deranged in several cancers and is as
Externí odkaz:
https://doaj.org/article/d132970361af45e49122cd4ff62db43f
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0162662 (2016)
A role for estrogens in breast cancer is widely accepted, however, recent evidence highlights that timing and exposure levels are important in determining whether they elicit harmful versus beneficial effects. The rat chemical carcinogen model has be
Externí odkaz:
https://doaj.org/article/b4c7b193a88b456aa4595dd8661df217
The breakthrough therapy designation (BTD) process was created to expedite clinical development timelines for drugs intended to treat serious conditions and preliminary clinical evidence indicates the drug may demonstrate substantial improvement over
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee9a623427b8a90dda27d95134966630
https://doi.org/10.1158/1078-0432.c.6532692.v1
https://doi.org/10.1158/1078-0432.c.6532692.v1
Autor:
Mark D Stewart, Diana Merino Vega, Rebecca C Arend, Jonathan F Baden, Olena Barbash, Nike Beaubier, Grace Collins, Tim French, Negar Ghahramani, Patsy Hinson, Petar Jelinic, Matthew J Marton, Kimberly McGregor, Jerod Parsons, Lakshman Ramamurthy, Mark Sausen, Ethan S Sokol, Albrecht Stenzinger, Hillary Stires, Kirsten M Timms, Diana Turco, Iris Wang, J Andrew Williams, Elaine Wong-Ho, Jeff Allen
Publikováno v:
The Oncologist. 27:167-174
Background Homologous recombination deficiency (HRD) is a phenotype that is characterized by the inability of a cell to effectively repair DNA double-strand breaks using the homologous recombination repair (HRR) pathway. Loss-of-function genes involv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29238611ea85f7aec2f04ff6e27ab25a
https://doi.org/10.1093/oncolo/oyab053
https://doi.org/10.1093/oncolo/oyab053
Autor:
Brittany A. McKelvey, Alexandra Berk, Lynda Chin, Stacie Hudgens, Ian Kudel, Ronan C. O'Hagan, Amila Patel, Julie Scott, Hillary Stires, Sam Wang, Debra Wujcik, Mark Stewart, Jeff Allen
Publikováno v:
JCO Clinical Cancer Informatics.
PURPOSE Using patient-reported outcomes (PROs) provides important insights from the patient's perspective and can be valuable to monitor and manage treatment-related adverse events during cancer treatment. Additionally, the digital administration of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e16307ceaaf53ed8d7a23de541901e67
https://doi.org/10.1200/cci.22.00161
https://doi.org/10.1200/cci.22.00161
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research.
Breakthrough therapy designation (BTD) is a valuable tool for expediting approval of promising therapies in oncology. Expediting drug development and review is time and resource intensive, so it is imperative to assess the performance of BTD and dete
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43736d10fcf462c251bba34cfc8f851d
https://pubmed.ncbi.nlm.nih.gov/35616593
https://pubmed.ncbi.nlm.nih.gov/35616593
Autor:
Hillary Stires, Richard Hughes, Alisa Vidulich, Zachary Zalewski, Chris Sloan, Manuel Avina, Hélène Hardy, Wing Chow, Joyce LaMori
Publikováno v:
AIDS research and human retroviruses. 37(11)
Antiretroviral therapies (ARTs) benefit millions with human immunodeficiency virus. However, concerns about subsequent weight gain and related metabolic complications have emerged. Early ARTs are associated with adipose tissue changes. While newer AR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20db5f843ca9b228766302a8639acb52
https://pubmed.ncbi.nlm.nih.gov/34541891
https://pubmed.ncbi.nlm.nih.gov/34541891
Autor:
Shaymaa Bahnassy, Carlos Benitez, M Idalia Cruz, Yanira Guerra, Shihong Ma, Sonali Persaud, Ganesh Raj, Rebecca Riggins, Hillary Stires, Ayodeji Olukoya
Publikováno v:
Journal of the Endocrine Society. 6:A880-A880
Approximately 75% of breast cancers are classified as hormone receptor-positive, most of which are estrogen receptor alpha-positive (ER+), which is the primary driver of growth in these tumors. Consequently, endocrine or anti-estrogen therapy is used
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::db724257c9b608516730451073301987
https://doi.org/10.1210/jendso/bvac150.1822
https://doi.org/10.1210/jendso/bvac150.1822
Autor:
Hillary Stires, Igor Bado, Thelma Brown, Martha Carlson, Isaac S. Chan, Gloria V. Echeverria, Andrew J. Ewald, Carla Lloyd, Julia Maues, Steffi Oesterreich, Robert N. Riter, Kelly Shanahan, Alana L. Welm, Josh Newby
Publikováno v:
Cancer Research. 82:1014-1014
The inclusion of patient advocates in basic cancer research has emerged as a valuable practice to ensure research is intentional, to support effective communication with broader audiences, and to directly connect researchers with those whom they are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::067d1791dc6b7c0652c15dcaaba10764
https://doi.org/10.1158/1538-7445.am2022-1014
https://doi.org/10.1158/1538-7445.am2022-1014