Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Hillary A. Hahm"'
Autor:
Hillary A. Hahm, N E Davidson
Publikováno v:
Endocrine Related Cancer. 5:199-211
Publikováno v:
Experimental Cell Research. 196:49-65
We have recently described a primary culture system which allows for extensive proliferation and functional differentiation of immature mammary epithelial cells. Herein, these findings are extended to demonstrate that a distinct pattern of ductal and
Publikováno v:
Journal of Clinical Oncology. 16:2280-2282
Autor:
Hillary A, Hahm, David S, Ettinger, Kathy, Bowling, Beth, Hoker, Tian Ling, Chen, Yelena, Zabelina, Robert A, Casero
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 8(3)
Polyamines are essential for tumor growth; consequently, agents that interfere with their metabolisms have been developed as antineoplastic agents. Diethylnorspermine (DENSPM) is one such agent. A focused Phase I clinical trial in patients with advan
Clinical aspects of cell death in breast cancer: the polyamine pathway as a new target for treatment
Publikováno v:
Endocrine-related cancer. 6(1)
Because intracellular polyamines have a critical role in cell proliferation and death pathways, the polyamine metabolic pathway represents a potential target for intervention in cancers. A number of polyamine analogues have been identified that downr
Publikováno v:
Apoptosis and Cancer Chemotherapy ISBN: 9781617371653
Apoptosis is an integral part of normal mammary gland development, differentiation, and function. Numerous descriptive and mechanistic studies of programmed cell death pathways in normal and malignant mammary cells have been presented. This chapter r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d1e27ccee0bba5f13d9b3ed2b4439f11
https://doi.org/10.1007/978-1-59259-720-8_19
https://doi.org/10.1007/978-1-59259-720-8_19
Autor:
Samuel R. Denmeade, John T. Isaacs, Diane E. McCloskey, Nancy E. Davidson, Ingrid B.J.K. Joseph, Hillary A. Hahm
Publisher Summary The breast and prostate cancer belong to the spectrum of hormone-related malignancies. So, this chapter seeks to review current knowledge about the role of programmed cell death in the normal development and function of the mammary
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::296caee9a8d070c54526c0995a7e7d4e
https://doi.org/10.1016/s1054-3589(08)61072-8
https://doi.org/10.1016/s1054-3589(08)61072-8
Autor:
Margot M. Ip, Kathleen M. Darcy, Suzanne Forczek, Hillary A. Hahm, Jennifer D. Black, Takami Oka, Wendy K. Shea, Masami Yoshimura
Publikováno v:
In vitro cellulardevelopmental biology : journal of the Tissue Culture Association. 26(8)
A serum-free primary culture system is described which allows normal rat mammary epithelial cells (RMECs) embedded within a reconstituted basement membrane to undergo extensive growth and functional differentiation as detected by synthesis and secret
Publikováno v:
Nature Medicine. 4:761-762
New clinical reports demonstrate that targeting the biological pathways of hormone and peptide growth factor receptors holds promise for the prevention and treatment of breast cancer.