Zobrazeno 1 - 10
of 799
pro vyhledávání: '"Hill, AV"'
An adenoviral-vectored vaccine confers seroprotection against capsular group B meningococcal disease
Autor:
Dold, C, Marsay, L, Wang, N, Silva-Reyes, L, Clutterbuck, E, Paterson, GK, Sharkey, K, Wyllie, D, Beernink, PT, Hill, AV, Pollard, AJ, Rollier, CS
Adenoviral-vectored vaccines are licensed for prevention of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and Ebola virus, but, for bacterial proteins, expression in a eukaryotic cell may affect the antigen's localization and conformat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1064::fb7f2ddaff5854b1adad4f9a2f62080b
https://ora.ox.ac.uk/objects/uuid:8c7167e6-a279-48fb-9adf-2d8b3c810cac
https://ora.ox.ac.uk/objects/uuid:8c7167e6-a279-48fb-9adf-2d8b3c810cac
Autor:
Marsay, L, Dold, C, Paterson, GK, Yamaguchi, Y, Derrick, JP, Chan, H, Feavers, IM, Maiden, MCJ, Wyllie, D, Hill, AV, Pollard, AJ, Rollier, CS
Publikováno v:
Marsay, L, Dold, C, Paterson, G K, Yamaguchi, Y, Derrick, J, Chan, H, Feavers, I M, Maiden, M C J, Wyllie, D, Hill, A V, Pollard, A J & Rollier, C S 2022, ' Viral vectors expressing group B meningococcal outer membrane proteins induce strong antibody responses but fail to induce functional bactericidal activity ', Journal Of Infection, vol. 84, no. 5, pp. 658-667 . https://doi.org/10.1016/j.jinf.2022.02.032
Marsay, L, Dold, C, Paterson, G K, Yamaguchi, Y, Derrick, J P, Chan, H, Feavers, I M, Maiden, M C J, Wyllie, DH, Hill, A V, Pollard, A J & Rollier, C S 2022, ' Viral Vectors Expressing Group B Meningococcal Outer Membrane Proteins Induce Strong Antibody Responses but Fail to Induce Functional Bactericidal Activity in Mice ', Journal of Infection, vol. 84, no. 5, pp. 658-667 . https://doi.org/10.1016/j.jinf.2022.02.032
Marsay, L, Dold, C, Paterson, G K, Yamaguchi, Y, Derrick, J P, Chan, H, Feavers, I M, Maiden, M C J, Wyllie, DH, Hill, A V, Pollard, A J & Rollier, C S 2022, ' Viral Vectors Expressing Group B Meningococcal Outer Membrane Proteins Induce Strong Antibody Responses but Fail to Induce Functional Bactericidal Activity in Mice ', Journal of Infection, vol. 84, no. 5, pp. 658-667 . https://doi.org/10.1016/j.jinf.2022.02.032
Objective Adenoviral vectored vaccines, with the appropriate gene insert, induce cellular and antibody responses against viruses, parasites and intracellular pathogens such as Mycobacterium tuberculosis. Here we explored their capacity to induce func
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fb6b584cbdc35569dbe0a54d7932ea4
https://doi.org/10.1016/j.jinf.2022.02.032
https://doi.org/10.1016/j.jinf.2022.02.032
Autor:
Mensah, VA, Gueye, A, Ndiaye, M, Edwards, NJ, Wright, D, Anagnostou, NA, Syll, M, Ndaw, A, Abiola, A, Bliss, C, Gomis, JF, Petersen, I, Ogwang, C, Dieye, T, Viebig, NK, Lawrie, AM, Roberts, R, Nicosia, A, Faye, B, Gaye, O, Leroy, O, Imoukhuede, EB, Ewer, KJ, Bejon, P, Hill, AV, Cisse, B, MVVC Group
Publikováno v:
PLoS ONE, Vol 11, Iss 12, p e0167951 (2016)
PLoS ONE
PLoS ONE
Malaria transmission is in decline in some parts of Africa, partly due to the scaling up of control measures. If the goal of elimination is to be achieved, additional control measures including an effective and durable vaccine will be required. Studi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ceb4fb38ef456ee241f2be0fcc599f86
https://doi.org/10.1371/journal.pone.0167951
https://doi.org/10.1371/journal.pone.0167951
Autor:
Venkatraman, N, Bowyer, G, Edwards, NJ, Griffiths, O, Powlson, J, Silman, D, Morter, R, Folegatti, PM, Minassian, AM, Poulton, ID, Collins, K, Brod, F, Angell-Manning, P, Berrie, E, Brendish, N, Glenn, G, Fries, L, Baum, J, Blagborough, AM, Roberts, R, Lawrie, AM, Lewis, DJ, Faust, SN, Gilbert, S, Ewer, KJ, Hill, AV
It remains a global health priority to develop a durable and highly efficacious malaria vaccine. The most advanced malaria vaccine candidate, RTS,S/AS01 has completed Phase III testing in a multicentre study across several African sites and demonstra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1064::cdeff7a19e2b23f37f8e072d98cfab76
https://ora.ox.ac.uk/objects/uuid:e433efac-8e80-4278-b303-3537df06b9f7
https://ora.ox.ac.uk/objects/uuid:e433efac-8e80-4278-b303-3537df06b9f7
Autor:
Rampling, T, Ewer, KJ, Bowyer, G, Edwards, NJ, Wright, D, Sridhar, S, Payne, R, Powlson, J, Bliss, C, Venkatraman, N, Poulton, ID, De Graaf, H, Gbesemete, D, Grobbelaar, A, Davies, H, Roberts, R, Angus, B, Ivinson, K, Weltzin, R, Rajkumar, B-Y, Wille-Reece, U, Lee, C, Ockenhouse, C, Sinden, R, Gerry, SC, Lawrie, A, Vekemans, J, Morelle, D, Lievens, M, Ballou, RW, Lewis, DJM, Cooke, GS, Faust, SN, Hill, AV
We assessed a combination multi-stage malaria vaccine schedule in which RTS,S/AS01B was given concomitantly with viral vectors expressing multiple-epitope thrombospondin-related adhesion protein (ME-TRAP) in a 0-month, 1-month, and 2-month schedule.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1032::dc212b786e31c4ff489f1ace7a3a24bc
http://hdl.handle.net/10044/1/64182
http://hdl.handle.net/10044/1/64182
Autor:
Tiono, AB, Ouedraogo, A, Coulibaly, SA, Bougouma, EC, Ouedraogo, IN, Navin, V, Bowyer, G, Ewer, K, Viebig, N, Diarra, A, Glenn, G, Leroy, O, Hill, AV, Sirima, SB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1064::462698e4ae7b417879334550a48ea7b3
https://ora.ox.ac.uk/objects/uuid:d75749e3-63f5-4ada-9877-29f72e5a2280
https://ora.ox.ac.uk/objects/uuid:d75749e3-63f5-4ada-9877-29f72e5a2280
Autor:
Sheehy, SH, Duncan, CJ, Elias, SC, Choudhary, P, Biswas, S, Halstead, FD, Collins, KA, Edwards, NJ, Douglas, AD, Anagnostou, NA, Ewer, KJ, Havelock, T, Mahungu, T, Bliss, CM, Miura, K, Poulton, ID, Lillie, PJ, Antrobus, RD, Berrie, E, Moyle, S, Gantlett, K, Colloca, S, Cortese, R, Long, CA, Sinden, RE, Gilbert, SC, Lawrie, AM, Doherty, T, Faust, SN, Nicosia, A, Hill, AV, Draper, SJ
Publikováno v:
Molecular Therapy; Vol 20
The induction of cellular immunity, in conjunction with antibodies, may be essential for vaccines to protect against blood-stage infection with the human malaria parasite Plasmodium falciparum. We have shown that prime-boost delivery of P. falciparum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::920ee07034340d4fcad34eaaf38094e5
Autor:
Hill, AV, Wainscoat, JS
DNA analysis of the alpha- and beta-globin gene clusters has revealed substantial variability between individuals and populations. As well as restriction enzyme site and length polymorphisms, variation in gene copy number and type is observed. Becaus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::7ce5a41838d9f1fac3b17b8189f7c850
https://ora.ox.ac.uk/objects/uuid:ec26227e-d876-41dd-bfe7-bfa96a46780e
https://ora.ox.ac.uk/objects/uuid:ec26227e-d876-41dd-bfe7-bfa96a46780e
Adenovirus vaccine vectors generated from new viral serotypes are routinely screened in pre-clinical laboratory animal models to identify the most immunogenic and efficacious candidates for further evaluation in clinical human and veterinary settings
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::7c1d107ce38446aee6b61e0f1703e09d
https://ora.ox.ac.uk/objects/uuid:bbfb6faa-a971-4e95-a567-b85ab2b30e7d
https://ora.ox.ac.uk/objects/uuid:bbfb6faa-a971-4e95-a567-b85ab2b30e7d
There is now considerable evidence that host genetic factors are important in determining the outcome of infection with Mycobacterium tuberculosis (MTB). The aim of this study was to assess the role of several candidate genes in the variation observe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::796189a1d9bd506667fdba7a29383a01
https://doi.org/10.1375/1369052042663887
https://doi.org/10.1375/1369052042663887