Platelet-derived growth factor activation of mitogen-activated protein kinase depends on the sequential activation of phosphatidylcholine-specific phospholipase C, protein kinase C-ζ and Raf-1

Autor: van Blitterswijk Wj, Hilkmann H, van Dijk Mc

Publikováno v: Biochemical Journal. 325:303-307

The mechanism of Raf-1 activation by platelet-derived growth factor (PDGF) is poorly defined. We previously reported that, in Rat-1 fibroblasts, PDGF activates a phosphatidylcholine-specific phospholipase C (PC-PLC) and that the product, diacylglycer

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2094824a7e4b8adc43de7a3ab18858c3
https://doi.org/10.1042/bj3250303

Noncanonical and reversible cysteine ubiquitination prevents the overubiquitination of PEX5 at the peroxisomal membrane.

Autor: Francisco, Tânia^1,2,3 (AUTHOR), Pedrosa, Ana G.^1,2,3 (AUTHOR), Rodrigues, Tony A.^1,2,3 (AUTHOR), Abalkhail, Tarad⁴ (AUTHOR), Li, Hongli⁵ (AUTHOR), Ferreira, Maria J.^1,2,3 (AUTHOR), van der Heden van Noort, Gerbrand J.⁶ (AUTHOR), Fransen, Marc⁵ (AUTHOR), Hettema, Ewald H.⁴ (AUTHOR), Azevedo, Jorge E.^1,2,3 (AUTHOR) jazevedo@ibmc.up.pt

Publikováno v: PLoS Biology. 3/12/2024, Vol. 22 Issue 3, p1-23. 23p.

Rigid plasma-membrane-derived vesicles, enriched in tumour-associated surface antigens (MLr), occurring in the ascites fluid of a murine leukaemia (GRSL).

Autor: van Blitterswijk, W. J., Emmelot, P., Hilkmann, H. A. M., Hilgers, J., Feltkamp, C. A.

Publikováno v: International Journal of Cancer; Jan1979, Vol. 23 Issue 1, p62-70, 9p

High-throughput epitope discovery reveals frequent recognition of neo-antigens by CD4+ T cells in human melanoma.

Autor: Linnemann C; Division of Immunology, The Netherlands Cancer Institute, Amsterdam, the Netherlands., van Buuren MM; Division of Immunology, The Netherlands Cancer Institute, Amsterdam, the Netherlands., Bies L; Division of Immunology, The Netherlands Cancer Institute, Amsterdam, the Netherlands., Verdegaal EM; Department of Clinical Oncology, Leiden University Medical Center, Leiden, the Netherlands., Schotte R; AIMM Therapeutics B.V., Amsterdam, the Netherlands., Calis JJ; Division of Immunology, The Netherlands Cancer Institute, Amsterdam, the Netherlands., Behjati S; Cancer Genome Project, Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, United Kingdom., Velds A; Central Genomics Facility, The Netherlands Cancer Institute, Amsterdam, the Netherlands., Hilkmann H; Peptide Synthesis Facility, The Netherlands Cancer Institute, Amsterdam, the Netherlands., Atmioui DE; Peptide Synthesis Facility, The Netherlands Cancer Institute, Amsterdam, the Netherlands., Visser M; Department of Clinical Oncology, Leiden University Medical Center, Leiden, the Netherlands., Stratton MR; Cancer Genome Project, Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, United Kingdom., Haanen JB; 1] Division of Immunology, The Netherlands Cancer Institute, Amsterdam, the Netherlands. [2] Division of Medical Oncology, The Netherlands Cancer Institute, Amsterdam, the Netherlands., Spits H; AIMM Therapeutics B.V., Amsterdam, the Netherlands., van der Burg SH; Department of Clinical Oncology, Leiden University Medical Center, Leiden, the Netherlands., Schumacher TN; Division of Immunology, The Netherlands Cancer Institute, Amsterdam, the Netherlands.

Publikováno v: Nature medicine [Nat Med] 2015 Jan; Vol. 21 (1), pp. 81-5. Date of Electronic Publication: 2014 Dec 22.

Role of T Lymphocytes in Glioma Immune Microenvironment: Two Sides of a Coin.

Autor: Noor, Laiba, Upadhyay, Arun, Joshi, Vibhuti

Publikováno v: Biology (2079-7737); Oct2024, Vol. 13 Issue 10, p846, 20p