Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Hilkka Järventaus"'
Autor:
Minnamari Vippola, Maciej Stępnik, Hanna K. Lindberg, Hilkka Järventaus, Julia Catalán, Joanna Roszak, Satu Suhonen, Hannu Norppa
Publikováno v:
Mutation Research/Genetic Toxicology and Environmental Mutagenesis. 805:7-18
Data available on the genotoxicity of zinc oxide (ZnO) nanoparticles (NPs) are controversial. Here, we examined the effects of particle size and dispersion status on the cytotoxicity and genotoxicity of nanosized and fine ZnO, in the presence and abs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cfeec73197e7ae95df30d4d3f3ec163
https://doi.org/10.1016/j.mrgentox.2016.05.008
https://doi.org/10.1016/j.mrgentox.2016.05.008
Autor:
Hannu Norppa, Ari Hirvonen, Christopher R. Jones, Gabriele Sabbioni, Huifang Yan, Hilkka Järventaus, Ovnair Sepai
Publikováno v:
Biomarkers. 21:721-730
Biomonitoring methods were applied to workers exposed to high levels of chloronitrobenzenes. The external dose, internal dose, biologically effective dose, and biological effects were determined. Individual susceptibility was assessed by analyzing ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8535ff5f70db9c55a4e3e0cd73a2396c
https://doi.org/10.3109/1354750x.2016.1172116
https://doi.org/10.3109/1354750x.2016.1172116
Autor:
Keld Alstrup Jensen, Esa Vanhala, Antti Joonas Koivisto, Satu Suhonen, Hilkka Järventaus, Kirsten Inga Kling, Carlos Moreno, Kirsi Siivola, Hannu Norppa, Penny Nymark, Hanna K. Lindberg, Kai Savolainen, Julia Catalán, Henrik Wolff
Publikováno v:
Nanotoxicology. 10:794-806
Some multi-walled carbon nanotubes (MWCNTs) induce mesothelioma in rodents, straight MWCNTs showing a more pronounced effect than tangled MWCNTs. As primary and secondary genotoxicity may play a role in MWCNT carcinogenesis, we used a battery of assa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bad9dc0ad31e7a92fa31ee59ae02e10
https://doi.org/10.3109/17435390.2015.1132345
https://doi.org/10.3109/17435390.2015.1132345
Autor:
Harri Alenius, Hilkka Järventaus, Hannu Norppa, Julia Catalán, Kati-Susanna Hannukainen, Kai Savolainen, Eero Kontturi, Marit Ilves, Esa Vanhala
Publikováno v:
Environmental and Molecular Mutagenesis. 56:171-182
Nanocellulosics are among the most promising innovations for a wide-variety of applications in materials science. Although nanocellulose is presently produced only on a small scale, its possible toxic effects should be investigated at this early stag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d687c8193bea777a414fc563919d63a
https://doi.org/10.1002/em.21913
https://doi.org/10.1002/em.21913
Autor:
Hannu Norppa, Kai Savolainen, Hilkka Järventaus, Minnamari Vippola, Julia Catalán, Satu Suhonen, Penny Nymark, Keld Alstrup Jensen, Renie K. Birkedal, Per Axel Clausen
Publikováno v:
Toxicology
Toxicology, 313(1), 38-48. Elsevier Ireland Ltd
Toxicology, 313(1), 38-48. Elsevier Ireland Ltd
Silver nanoparticles (AgNPs) are widely utilized in various consumer products and medical devices, especially due to their antimicrobial properties. However, several studies have associated these particles with toxic effects, such as inflammation and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8d7a4536443e0a4be3755c8cdc8d534
https://doi.org/10.1016/j.tox.2012.09.014
https://doi.org/10.1016/j.tox.2012.09.014
Autor:
Hannu Norppa, Peter B. Farmer, Rajinder Singh, Hanna K. Lindberg, Ghita C.-M. Falck, Kai Savolainen, Satu Suhonen, Julia Catalán, Esa Vanhala, Hilkka Järventaus
Publikováno v:
Toxicology. 313:24-37
Although some types of carbon nanotubes (CNTs) have been described to induce mesothelioma in rodents and genotoxic effects in various cell systems, there are few previous studies on the genotoxicity of CNTs in mesothelial cells. Here, we examined in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d84d9d7b0b696bced601e1ab74b0257a
https://doi.org/10.1016/j.tox.2012.12.008
https://doi.org/10.1016/j.tox.2012.12.008
Autor:
Harri Alenius, Ghita C.-M. Falck, Carlos Moreno, Antti Joonas Koivisto, Satu Suhonen, Kai Savolainen, Hilkka Järventaus, Yrjö Peltonen, Timo Tuomi, Hannu Norppa, Hanna K. Lindberg, Heli Nykäsenoja, Elina M. Rossi, Julia Catalán
Publikováno v:
Mutation Research/Genetic Toxicology and Environmental Mutagenesis. 745:58-64
In vitro studies have suggested that nanosized titanium dioxide (TiO(2)) is genotoxic. The significance of these findings with respect to in vivo effects is unclear, as few in vivo studies on TiO(2) genotoxicity exist. Recently, nanosized TiO(2) admi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c30d0d05a46bc4fe3ba6d216c89aec2b
https://doi.org/10.1016/j.mrgentox.2011.10.011
https://doi.org/10.1016/j.mrgentox.2011.10.011
Publikováno v:
Nanotoxicology. 6:825-836
We examined if three commercially available nanomaterials - short singlewall carbon nanotubes (SWCNTs), short multiwall carbon nanotubes (MWCNTs) and nanosized titanium dioxide anatase (TiO(2); primary particle size
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b50bab17e9f57bd5fde386e35c8bf1b2
https://doi.org/10.3109/17435390.2011.625130
https://doi.org/10.3109/17435390.2011.625130
Autor:
Ghita C.-M. Falck, Xu Wang, Hannu Norppa, Michael Fenech, Hanna K. Lindberg, Hilkka Järventaus
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 617:33-45
Micronuclei are formed from chromosomes and chromosomal fragments that lag behind in anaphase and are left outside daughter nuclei in telophase. They may also be derived from broken anaphase bridges. Nuclear buds, micronucleus-like bodies attached to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c753fed15111d7f5537cf4bd7a84a87
https://doi.org/10.1016/j.mrfmmm.2006.12.002
https://doi.org/10.1016/j.mrfmmm.2006.12.002
Autor:
Ari Hirvonen, Hannu Norppa, Gabriele Sabbioni, L. R. Brooks, Huifang Yan, B. Bäck, Y. Y. Liu, David M. DeMarini, Y. Zheng, Sarah H. Warren, Hilkka Järventaus, Ovnair Sepai
Publikováno v:
Biomarkers. 12:21-37
2,4,6-Trinitrotoluene (TNT) is an important occupational and environmental pollutant. In TNT-exposed humans, notable toxic manifestations have included aplastic anaemia, toxic hepatitis, cataracts, hepatomegaly, and liver cancer. Therefore, methods w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a61614b89a4449b359132e553f7a0d66
https://doi.org/10.1080/13547500600807012
https://doi.org/10.1080/13547500600807012