Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Hilke Vervenne"'
Autor:
Eva Boonen, Mette Bjerre, Daniel Berckmans, Hilke Vervenne, Jean-Marie Aerts, Torben Hansen, Geert Meyfroidt, Philippe Meersseman, Fabian Güiza, G Van den Berghe, Tim Tambuyzer
Publikováno v:
Tambuyzer, T, Guiza, F, Boonen, E, Meersseman, P, Vervenne, H, Hansen, T K, Bjerre, M, Van den Berghe, G, Berckmans, D, Aerts, J M & Meyfroidt, G 2017, ' Heart rate time series characteristics for early detection of infections in critically ill patients ', Journal of Clinical Monitoring and Computing, vol. 31, no. 2, pp. 407-415 . https://doi.org/10.1007/s10877-016-9870-4
It is difficult to make a distinction between inflammation and infection. Therefore, new strategies are required to allow accurate detection of infection. Here, we hypothesize that we can distinguish infected from non-infected ICU patients based on d
Autor:
Hilke Vervenne, Emilie De Samblanx, Eva Boonen, Lisa Van Dijck, Zoë Pironet, Lies Langouche, Thomas Janssens, Inge Derese, Sarah Vander Perre, Philippe Meersseman, Greet Van den Berghe
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism
Adrenal insufficiency is considered to be prevalent during critical illness, although the pathophysiology, diagnostic criteria, and optimal therapeutic strategy remain controversial. During critical illness, reduced cortisol breakdown contributes sub
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c0ba4eab068f8d9c20853e038066a76
https://lirias.kuleuven.be/handle/123456789/458382
https://lirias.kuleuven.be/handle/123456789/458382
Autor:
Philippe Meersseman, Johannes D. Veldhuis, Geert Meyfroidt, Eva Boonen, Hilke Vervenne, Greet Van den Berghe, Fabian Güiza, Pieter Wouters
Publikováno v:
AJP: Endocrinology and Metabolism
Recently, during critical illness, cortisol metabolism was found to be reduced. We hypothesize that such reduced cortisol breakdown may suppress pulsatile ACTH and cortisol secretion via feedback inhibition. To test this hypothesis, nocturnal ACTH an
Autor:
Ruth Andrew, Peter Declercq, Eva Boonen, Philippe Meersseman, Leen Mortier, Yoo-Mee Vanwijngaerden, Hilke Vervenne, Sarah Vander Perre, Lies Langouche, Isabel Spriet, Pieter J. Woutlers, Ilse Vanhorebeek, Brian R. Walker, Greet Van den Berghe
Publikováno v:
Boonen, E, Vervenne, H, Meersseman, P, Andrew, R, Mortier, L, Declercq, P E, Vanwijngaerden, Y-M, Spriet, I, Wouters, P J, Vander Perre, S, Langouche, L, Vanhorebeek, I, Walker, B R & Van den Berghe, G 2013, ' Reduced Cortisol Metabolism during Critical Illness ', New England Journal of Medicine, vol. 368, no. 16, pp. 1477-1488 . https://doi.org/10.1056/NEJMoa1214969
BACKGROUNDCritical illness is often accompanied by hypercortisolemia, which has been attributed to stress-induced activation of the hypothalamic-pituitary-adrenal axis. However, low corticotropin levels have also been reported in critically ill patie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c5516a5a07ffb80e7bbb0659ce7e7ff
https://hdl.handle.net/20.500.11820/893b0f26-d9e8-4d15-b370-794924ed6372
https://hdl.handle.net/20.500.11820/893b0f26-d9e8-4d15-b370-794924ed6372
Autor:
Lars Larsson, Eric-Jan Ververs, Hilke Vervenne, Ilse Vanhorebeek, Sarah Derde, Birthe Fahrenkrog, Wim Martinet, Jan Gunst, Inge Derese, Greet Van den Berghe, Fabian Güiza
Publikováno v:
Endocrinology
Muscular and hepatic abnormalities observed in artificially fed critically ill patients strikingly resemble the phenotype of autophagy-deficient mice. Autophagy is the only pathway to clear damaged organelles and large ubiquitinated proteins and aggr
Autor:
Hilke Vervenne, Greet Van den Berghe
Critical illness is any condition requiring support of failing vital organ systems, without which survival would not be possible. It is characterized by striking alterations in the hypothalamic-anterior-pituitary axes that are known to contribute to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::322a085f9c581f71ae39f1856e7fce8b
https://doi.org/10.1093/med/9780199235292.003.0177
https://doi.org/10.1093/med/9780199235292.003.0177
Autor:
Koen R.M.O. Crombez, Wim J.M. Van de Ven, Marleen M.R. Petit, Veerle Janssens, Hilke Vervenne, Els L.D. Delvaux
Publikováno v:
Biochemical and biophysical research communications. 379(2)
LPP (Lipoma Preferred Partner) is a zyxin-related cell adhesion protein that is involved in the regulation of cell migration. We generated mice with a targeted disruption of the Lpp gene and analysed the importance of Lpp for embryonic development an
Publikováno v:
FEBS letters. 579(22)
The zyxin family of proteins consists of five members, ajuba, LIMD1, LPP, TRIP6 and zyxin, which localize at cell adhesion sites and shuttle to the nucleus. Previously, we established that LPP interacts with the tumor suppressor Scrib, a member of th
Autor:
Peter Declercq, Eva Boonen, G Van den Berghe, Pieter Wouters, Leen Mortier, Paola Fierabracci, Hilke Vervenne, Brian R. Walker, Isabel Spriet, Yoo-Mee Vanwijngaerden, Philippe Meersseman, Ilse Vanhorebeek, S Vander Perre, Ruth Andrew, Lies Langouche
Publikováno v:
L'Endocrinologo. 14:93-93
Autor:
Ilse Vanhorebeek, Eva Boonen, Yoo-Mee Vanwijngaerden, Hilke Vervenne, Lies Langouche, Philippe Meersseman, Isabel Spriet, G Van den Berghe, Leen Mortier
Publikováno v:
Critical Care
Critical illness is hallmarked by elevated cortisol levels, reflecting the severity of illness. Paradoxically, previous studies reported suppressed ACTH, implicating another mechanism driving elevated cortisol during critical illness. We hypothesized