Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Hildegard Meissner"'
Autor:
Katrin Lamszus, Nils Ole Schmidt, Manfred Westphal, Robert Soriano, Zora Modrusan, Hildegard Meissner, Heidi S. Phillips, Samir Kharbanda, Dirk Kemming, Hauke S. Günther
Publikováno v:
Oncogene. 27:2897-2909
Tumor cells with stem cell-like properties can be cultured from human glioblastomas by using conditions that select for the expansion of neural stem cells. We generated cell lines from glioblastoma specimens with the goal to obtain model systems for
Publikováno v:
Acta Neurochirurgica. 144:71-87
We have previously identified thromboxane synthase as an important regulator of glioma cell migration. Inhibitors of this enzyme abrogate cell motility and induce apoptosis. However, the formation rate of thromboxanes is indirectly dependent on the a
Publikováno v:
Cancer Genetics and Cytogenetics. 110:103-110
Meningiomas are usually benign tumors; however, they can recur after surgical resection and occasionally show histological progression to a higher malignancy grade. Five such rare cases of aggressively recurring meningiomas were present in our depart
Publikováno v:
Glia. 22:415-420
The human neurotropic papovavirus JC, a close relative of simian virus 40, has been associated with the formation of brain tumors in humans because of its ability to induce such tumors in other primates under experimental conditions. Here we have ana
Publikováno v:
Journal of Neurocytology. 27:805-816
Cell cultures were established from three human neurocytoma specimens (primary and recurrent). The phenotypic evolution was analyzed by immunocytology in different culture conditions in the presence and absence of serum including the addition of epid
Autor:
Mark X. Sliwkowski, Julie A. Lofgren, Eva Szonyi, Manfred Westphal, Karoly Nikolics, Hildegard Meissner, Wolfgang Hamel, Leonie Meima
Publikováno v:
Journal of Neuro-Oncology. 35:335-346
The activation of autocrine loops involving proto-oncogene related receptor tyrosine kinases has led to the analysis of a large number of growth factor systems in human glioma specimens and cell lines. The ErbB-2 system, also called HER-2 or neu, is
Publikováno v:
Neurosurgery. :755-764
Histoanatomically invading astrocytoma cells appear to migrate along distinct structures within the brain. Astrocytoma invasion may occur along extracellular matrix (ECM) protein-containing structures, such as blood vessels, but most frequently occur
Autor:
Manfred Westphal, Hildegard Meissner, Maria Demestre, Nils Ole Schmidt, Jan Sedlacik, Seung U. Kim, Jens Fiehler, Matthias Reitz
Stem cell-based therapies for neurological disorders, including brain tumors, advance continuously toward clinical trials. Optimized cell delivery to the central nervous system remains a challenge since direct intracerebral injection is an invasive m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9ed09a8d4205b83d2bab15d08042dce
https://europepmc.org/articles/PMC3659670/
https://europepmc.org/articles/PMC3659670/
Autor:
Wolfgang Deppert, Hildegard Meissner, Hirotaka Yamamoto, Erwin G. Van Meir, Rolf M Nüsing, Willy Günther, Kimio Yoshizato, Srenja Zapf, Ella Kim, Alf Giese
Publikováno v:
Oncogene. 22(49)
Cancer formation and progression is a complex process determined by several mechanisms that promote cell growth, invasiveness, neo-angiogenesis, and render neoplastic cells resistant to apoptosis. The tumor suppressor p53 and the proto-oncogenic fact