Výsledky vyhledávání - "Hilde De Man"

In vivo visualization and quantification of (Disturbed) Oatp-mediated hepatic uptake and Mrp2-mediated biliary excretion of 99mTc-mebrofenin in mice

Autor: Lieselotte Moerman, Maarten Vliegen, Hilde De Man, Maarten T. Huisman, Geert Mannens, Christian Vanhove, Caroline Dumolyn, Filip De Vos, Sara Neyt

Publikováno v: Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 54(4)

Hepatic transport of 99mTc-mebrofenin through organic anion transport protein 1a and 1b (Oatp1a/1b) and multidrug resistance protein 2 (Mrp2) was investigated by small-animal SPECT. On the basis of the results, a noninvasive method to visualize and q

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e698b1c2755b10a6dcfc528e2428f7fa
https://pubmed.ncbi.nlm.nih.gov/23440558

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Powder for reconstitution of the anti-HIV-1 drug TMC278 - Formulation development, stability and animal studies

Autor: Murali Pendela, Pieter Van Remoortere, Wigerinck Piet Tom Bert Paul, Hilde De Man, Laurent Schueller, Marie-Paule Bouche, Elke Van Gyseghem, Jan Rosier, Guy Van den Mooter, Gerben Albert Eleutherius Van 'T Klooster, Lieven Baert, Jos Hoogmartens, Erwin Adams

Publikováno v: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 70(3)

Powders for reconstitution of the next-generation non-nucleoside reverse transcriptase inhibitor (NNRTI) TMC278 with low water solubility were developed by using a spray-dry technology. Their flexible dosing ability makes them suitable for patients l

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04ed7afe6e8609d758ffe7d3243786e6
https://pubmed.ncbi.nlm.nih.gov/18657611

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