Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Hilde, Stubdal"'
Autor:
Rosana Kapeller, Olga Charlat, Troy Chickering, Judy H. Dunmore, Dennis Huszar, James Deeds, Catherine A. Lynch, Qing Fang, Patrick W. Kleyn, Victoria Fairchild-Huntress, Hilde Stubdal, Ann Moriarty
Publikováno v:
Molecular and Cellular Biology. 20:878-882
The mouse tubby phenotype is characterized by maturity-onset obesity accompanied by retinal and cochlear degeneration. A positional cloning effort to find the gene responsible for this phenotype led to the identification of tub, a member of a novel g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dcf5a4ef57742e5012e27ee2bf0ec2d
https://doi.org/10.1128/mcb.20.3.878-882.2000
https://doi.org/10.1128/mcb.20.3.878-882.2000
Autor:
Jay P. Morgenstern, Rosana Kapeller, James Lillie, Ann Moriarty, Elizabeth Siebert, Louis A. Tartaglia, Troy Chickering, Hilde Stubdal, Kelly Theriault, Ann Strauss
Publikováno v:
Journal of Biological Chemistry. 274:24980-24986
A mutation in the tub gene leads to maturity-onset obesity, insulin resistance, and progressive retinal and cochlear degeneration in mice. tub is a member of a growing family of genes that encode proteins of unknown function that are remarkably conse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2958c9a031eb7126ea29b6bd43bd802a
https://doi.org/10.1074/jbc.274.35.24980
https://doi.org/10.1074/jbc.274.35.24980
Publikováno v:
Molecular and Cellular Biology. 18:1408-1415
Transformation by simian virus 40 large T antigen (TAg) is dependent on the inactivation of cellular tumor suppressors. Transformation minimally requires the following three domains: (i) a C-terminal domain that mediates binding to p53; (ii) the LXCX
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bb08ddc642f310fc301bda63a0a2e65
https://doi.org/10.1128/mcb.18.3.1408
https://doi.org/10.1128/mcb.18.3.1408
Autor:
Kathryn S. Campbell, Hilde Stubdal, Colleen Schweitzer, Juan Zalvide, James A. DeCaprio, Thomas M. Roberts
Publikováno v:
Molecular and Cellular Biology. 17:4979-4990
Inactivation of the retinoblastoma tumor suppressor protein (pRB) contributes to tumorigenesis in a wide variety of cancers. In contrast, the role of the two pRB-related proteins, p130 and p107, in oncogenic transformation is unclear. The LXCXE domai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::361fd0ad197b71868d39f592b23eff61
https://doi.org/10.1128/mcb.17.9.4979
https://doi.org/10.1128/mcb.17.9.4979
Autor:
Karen P. Mullane, Kathryn S. Campbell, Juan Zalvide, James A. DeCaprio, Brian Schaffhausen, James M. Pipas, Pamela A. Silver, Thomas M. Roberts, I A Aksoy, Hilde Stubdal
Publikováno v:
Genes & Development. 11:1098-1110
The amino-terminal domain of SV40 large tumor antigen (TAg) is required for efficient viral DNA replication. However, the biochemical activity associated with this domain has remained obscure. We show here that the amino-terminal domain of TAg shares
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73176531d8a8de601db53c753ad1efe8
https://doi.org/10.1101/gad.11.9.1098
https://doi.org/10.1101/gad.11.9.1098
Autor:
Hilde, Stubdal, Noah, Perin, Marilyn, Lemmon, Patricia, Holman, Maxine, Bauzon, Philip M, Potter, Mary K, Danks, Ali, Fattaey, Thomas, Dubensky, Leisa, Johnson
Publikováno v:
Cancer research. 63(20)
ONYX-015 has been used successfully in the clinic as a cancer therapeutic in combination with chemotherapy. The combination of ONYX-015 and chemotherapy appears to be more efficacious than either regimen alone. In this study, we try to enhance this c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c3657c1f8b62bab546b3d69fe1431f5d
https://pubmed.ncbi.nlm.nih.gov/14583489
https://pubmed.ncbi.nlm.nih.gov/14583489
Publikováno v:
Journal of virology. 70(5)
p130 and p107 are nuclear phosphoproteins related to the retinoblastoma gene product (pRb). pRb, p107, and p130 each undergo cell cycle-dependent phosphorylation, form complexes with the E2F family of transcription factors, and associate with oncopro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51f7e53735c0687cb8fe68b2f92fa8ab
https://pubmed.ncbi.nlm.nih.gov/8627752
https://pubmed.ncbi.nlm.nih.gov/8627752