Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Hilda Petrs-Silva"'
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 33, Iss , Pp 845-847 (2023)
Externí odkaz:
https://doaj.org/article/2bdc0a9f85d84339ac5c7612a281973d
Publikováno v:
Cells, Vol 12, Iss 17, p 2155 (2023)
Advances in RNA-sequencing technologies have led to the identification of molecular biomarkers for several diseases, including neurodegenerative diseases, such as Alzheimer’s, Parkinson’s, Huntington’s diseases and Amyotrophic Lateral Sclerosis
Externí odkaz:
https://doaj.org/article/b99330ce549c473ab8da6f38fce3cdbe
Autor:
Mariana Santana Dias, Xiaoyue Luo, Vinicius Toledo Ribas, Hilda Petrs-Silva, Jan Christoph Koch
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 7, p 3935 (2022)
Glaucoma is a neurodegenerative disease that affects the retinal ganglion cells (RGCs) and leads to progressive vision loss. The first pathological signs can be seen at the optic nerve head (ONH), the structure where RGC axons leave the retina to com
Externí odkaz:
https://doaj.org/article/1eb7c90db7904b74aef067b6bf9b4c44
Autor:
Gabriel Nascimento-dos-Santos, Eduardo de-Souza-Ferreira, Rafael Linden, Antonio Galina, Hilda Petrs-Silva
Publikováno v:
Cells, Vol 10, Iss 7, p 1827 (2021)
Mitochondria are key players of aerobic respiration and the production of adenosine triphosphate and constitute the energetic core of eukaryotic cells. Furthermore, cells rely upon mitochondria homeostasis, the disruption of which is reported in path
Externí odkaz:
https://doaj.org/article/a6b21d27e5f3485caa4c989288a661e3
Autor:
Pedro Henrique Victorino, Camila Marra, Dumitru Andrei Iacobas, Sanda Iacobas, David C. Spray, Rafael Linden, Daniel Adesse, Hilda Petrs-Silva
Publikováno v:
Genes, Vol 12, Iss 3, p 403 (2021)
Glaucoma is a multifactorial neurodegenerative disease, characterized by degeneration of the retinal ganglion cells (RGCs). There has been little progress in developing efficient strategies for neuroprotection in glaucoma. We profiled the retina tran
Externí odkaz:
https://doaj.org/article/b5be9afbc7a546bfb4675ce39c70422f
Autor:
Sabrina V. Martini, Adriana L. Silva, Debora Ferreira, Rafael Rabelo, Felipe M. Ornellas, Karina Gomes, Patricia R.M. Rocco, Hilda Petrs-Silva, Marcelo M. Morales
Publikováno v:
Cellular Physiology and Biochemistry, Vol 39, Iss 2, Pp 544-553 (2016)
Background/Aims: Adeno-associated virus (AAV) vectors are being increasingly used as the vector of choice for in vivo gene delivery and gene therapy for many pulmonary diseases. Recently, it was shown that phosphorylation of surface-exposed tyrosine
Externí odkaz:
https://doaj.org/article/236f387813df470e89a874b843b99674
Autor:
Mariana Santana Dias, Victor Guedes de Araujo, Rafael Lani-Louzada, Rafael Linden, Vinicius Toledo Ribas, Hilda Petrs-Silva
Glaucoma is a chronic and multifactorial neurodegenerative disease marked by structural damage to the optic nerve with axonal loss, progressive retinal ganglion cell degeneration, and optic disc excavation. Both high intraocular pressure and aging ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0c68881ca986d73e341afb35af7a132
https://mts.intechopen.com/articles/show/title/perspective-on-gene-therapy-for-glaucoma
https://mts.intechopen.com/articles/show/title/perspective-on-gene-therapy-for-glaucoma
Autor:
Sabrina V. Martini, Adriana L. da Silva, Debora Ferreira, Karina Gomes, Felipe M. Ornellas, Miquéias Lopes-Pacheco, Emilia Zin, Hilda Petrs-Silva, Patricia R. M. Rocco, Marcelo M. Morales
Publikováno v:
Cellular Physiology and Biochemistry, Vol 34, Iss 3, Pp 681-690 (2014)
Background/Aims: Vectors derived from adeno-associated viruses (AAVs) are important gene delivery tools for treating pulmonary diseases. Phosphorylation of surface-exposed tyrosine residues from AAV2 capsid targets the viral particles for ubiquitinat
Externí odkaz:
https://doaj.org/article/ccdddfa82e1e4861bb714835ced6be07
Autor:
Rafael Linden, Hilda Petrs-Silva, Mariana S. Dias, Victor G. Araújo, Carla Andreia Abreu, Rafael Lani-Louzada
Publikováno v:
Journal of visualized experiments : JoVE. (180)
Glaucoma, the second leading cause of blindness worldwide, is a heterogeneous group of ocular disorders characterized by structural damage to the optic nerve and retinal ganglion cell (RGC) degeneration, resulting in visual dysfunction by interruptin
Autor:
Hilda Petrs-Silva, Adalmir Morterá Dantas, Carla Andreia Abreu, Mariana Santana Dias, Gabriel Nascimento-dos-Santos, Silvana Allodi, Thais Gonçalo, Mario Fiorani, Victor Guedes de Araujo, Rafael Lani, Rafael Linden
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-13 (2019)
Scientific Reports
Scientific Reports
Glaucoma is a neurodegenerative disorder characterized by the progressive functional impairment and degeneration of the retinal ganglion cells (RGCs) and their axons, and is the leading cause of irreversible blindness worldwide. Current management of