Cholinergic receptor activation on epithelia protects against cytokine-induced barrier dysfunction

Autor: Dhawan, S., Hiemstra, I. H., Verseijden, C., Hilbers, F. W., te Velde, A. A., Willemsen, L. E.M., Stap, J., den Haan, J. M., de Jonge, W. J., Sub Immunopharmacology, Pharmacology

Publikováno v: Acta Physiologica, 213(4), 846. Wiley-Blackwell
Acta physiologica (Oxford, England), 213(4), 846-859. Wiley-Blackwell
Dhawan, S, Hiemstra, I H, Verseijden, C, Hilbers, F W, te Velde, AA, Willemsen, L E M, Stap, J, den Haan, J M M & de Jonge, W J 2015, ' Cholinergic receptor activation on epithelia protects against cytokine-induced barrier dysfunction ', Acta Physiologica, vol. 213, no. 4, pp. 846-859 . https://doi.org/10.1111/apha.12469
Acta Physiologica, 213(4), 846-859. Wiley-Blackwell

Aim Various types of cholinergic receptors are expressed on intestinal epithelia. Their function is not completely understood. We hypothesize that cholinergic receptor activation on epithelium may serve a protective function in cytokine-induced barri

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57fb7916b0aeb8c68a9e5324a5fbbdbf
https://doi.org/10.1111/apha.12469

A JAK1 Selective Kinase Inhibitor and Tofacitinib Affect Macrophage Activation and Function.

Autor: Vries, L C S De, Duarte, J M, Krijger, M De, Welting, O, Hamersveld, P H P Van, Leeuwen-Hilbers, F W M Van, Moerland, P D, Jongejan, A, D'Haens, G R, Jonge, W J De, Wildenberg, M E

Publikováno v: Inflammatory Bowel Diseases; Apr2019, Vol. 25 Issue 4, p647-660, 14p

Mast cells trigger epithelial barrier dysfunction, bacterial translocation and postoperative ileus in a mouse model

Autor: Snoek, S. A., Dhawan, S., van Bree, S. H., Cailotto, C., van Diest, S. A., Duarte, J. M., Stanisor, O. I., Hilbers, F. W., Nijhuis, L., Koeman, A., van den Wijngaard, R. M., Zuurbier, C. J., Boeckxstaens, G. E., de Jonge, W. J.

Publikováno v: Neurogastroenterology and motility, 24(2), 172-E91. Wiley-Blackwell

Background Abdominal surgery involving bowel manipulation commonly results in inflammation of the bowel wall, which leads to impaired intestinal motility and postoperative ileus (POI). Mast cells have shown to play a key role in the pathogenesis of P

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::08c2c2066b5ab44458241f1a679521f0
https://pure.amc.nl/en/publications/mast-cells-trigger-epithelial-barrier-dysfunction-bacterial-translocation-and-postoperative-ileus-in-a-mouse-model(dd9fc2c1-cfcf-4659-b28c-e60110479669).html

Sympathetic Innervation Modulates Mucosal Immune Homeostasis and Epithelial Host Defense.

Autor: Mallesh, Shilpashree¹ (AUTHOR), Ten Hove, Anne S.² (AUTHOR), Schneider, Reiner¹ (AUTHOR), Schneiker, Bianca¹ (AUTHOR), Efferz, Patrik¹ (AUTHOR), Kalff, Jörg C.¹ (AUTHOR), de Jonge, Wouter J.^1,2 (AUTHOR), Wehner, Sven¹ (AUTHOR) sven.wehner@ukbonn.de

Publikováno v: Cells (2073-4409). Aug2022, Vol. 11 Issue 16, p2606. 17p.

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