Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Hilary P. Stevenson"'
Autor:
Bahige G. Abdallah, Nadia A. Zatsepin, Shatabdi Roy-Chowdhury, Jesse Coe, Chelsie E. Conrad, Katerina Dörner, Raymond G. Sierra, Hilary P. Stevenson, Fernanda Camacho-Alanis, Thomas D. Grant, Garrett Nelson, Daniel James, Guillermo Calero, Rebekka M. Wachter, John C. H. Spence, Uwe Weierstall, Petra Fromme, Alexandra Ros
Publikováno v:
Structural Dynamics, Vol 2, Iss 4, Pp 041719-041719-14 (2015)
The advent and application of the X-ray free-electron laser (XFEL) has uncovered the structures of proteins that could not previously be solved using traditional crystallography. While this new technology is powerful, optimization of the process
Externí odkaz:
https://doaj.org/article/6d97a7a7a5594d6faf645c40f9e94ee4
Autor:
Aaron S. Brewster, Hilary P. Stevenson, E.L. Baxter, Xiaofeng Fu, Elena G. Kovaleva, Christopher O. Barnes, Daniel P. DePonte, Guillermo Calero, Aina E. Cohen
Publikováno v:
Archives of Biochemistry and Biophysics. 602:61-68
Serial femtosecond crystallography (SFX) employing high-intensity X-ray free-electron laser (XFEL) sources has enabled structural studies on microcrystalline protein samples at non-cryogenic temperatures. However, the identification and optimization
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd29f91dadba0c01e7fcc0c9e66c133a
https://doi.org/10.1016/j.abb.2016.02.011
https://doi.org/10.1016/j.abb.2016.02.011
Autor:
Monica Calero, Aina E. Cohen, Christopher O. Barnes, Irimpan I. Mathews, Guowu Lin, James F. Conway, Chaitan Khosla, Ted M. Ross, Hilary P. Stevenson, Alexander M. Makhov, Hugo Santamaria, Guillermo Calero, Andrea L. Edwards, Oliver B. Zeldin, S. Michael Soltis, Veeranagu Nagarajan
Publikováno v:
Proceedings of the National Academy of Sciences. 111:8470-8475
The current practice for identifying crystal hits for X-ray crystallography relies on optical microscopy techniques that are limited to detecting crystals no smaller than 5 μm. Because of these limitations, nanometer-sized protein crystals cannot be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3959999aa0d1745b76498efbc2f029c1
https://doi.org/10.1073/pnas.1400240111
https://doi.org/10.1073/pnas.1400240111
Autor:
Guillermo Calero, Jean-Pierre Vilardaga, Alexandre Gidon, Núria M. Pastor-Soler, Tomoyuki Watanabe, Hilary P. Stevenson, Frederic Jean-Alphonse, Claire Louet, Mohammad M. Al-bataineh, Ashok Khatri, Thomas J. Gardella
Publikováno v:
Nature chemical biology
Nature Chemical Biology
Nature Chemical Biology, Nature Publishing Group, 2014, 10 (9), pp.707-709. ⟨10.1038/nchembio.1589⟩
Nature Chemical Biology
Nature Chemical Biology, Nature Publishing Group, 2014, 10 (9), pp.707-709. ⟨10.1038/nchembio.1589⟩
International audience; The PTH receptor is to our knowledge one of the first G protein-coupled receptor (GPCR) found to sustain cAMP signaling after internalization of the ligand-receptor complex in endosomes. This unexpected model is adding a new d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b64ef1922c46f7440f595b99e27b455
http://europepmc.org/articles/PMC4138287
http://europepmc.org/articles/PMC4138287
Autor:
Soichi Wakatsuki, Axel T. Brunger, Irimpan I. Mathews, Oleg A. Zadvornyy, Yingssu Tsai, Vladimir Vinetsky, Ana Gonzalez, Nicholas K. Sauter, John W. Peters, Aaron S. Brewster, Elena G. Kovaleva, Artem Y. Lyubimov, Brian K. Kobilka, Guillermo Calero, William I. Weis, Winnie Brehmer, Monarin Uervirojnangkoorn, Silke Nelson, Thomas Eriksson, Oliver B. Zeldin, Hilary P. Stevenson, Keith O. Hodgson, Britt Hedman, Christopher O. Barnes, Henrik T. Lemke, Aina E. Cohen, Roberto Alonso-Mori, S.E. McPhillips, Aashish Manglik, Guowu Lin, J. Song, E.L. Baxter, James M. Holton, Johan Hattne, Diling Zhu, Clyde A. Smith, Yiping Feng, Laura Aguila, Michael Hollenbeck, Joseph F. Chang, Paul Ehrensberger, S. Michael Soltis, Andrew C. Kruse, Stephen Keable, Matthieu Chollet
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, vol 111, iss 48
The emerging method of femtosecond crystallography (FX) may extend the diffraction resolution accessible from small radiation-sensitive crystals and provides a means to determine catalytically accurate structures of acutely radiation-sensitive metall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::163e68023631f52b43faee182dd9215d
https://escholarship.org/uc/item/8b84b73q
https://escholarship.org/uc/item/8b84b73q
Autor:
Richard Bouley, Timothy N. Feinstein, J Darwin King, Naofumi Yui, Kenneth R. Hallows, Matthew J. Webber, Dennis Brown, Vanessa L. Wehbi, Jean-Pierre Vilardaga, Hilary P. Stevenson
Publikováno v:
The Journal of biological chemistry. 288(39)
The vasopressin type 2 receptor (V2R) is a critical G protein-coupled receptor (GPCR) for vertebrate physiology, including the balance of water and sodium ions. It is unclear how its two native hormones, vasopressin (VP) and oxytocin (OT), both stimu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56e33f1b7f51fc14ae68f24e4be377b6
https://pubmed.ncbi.nlm.nih.gov/23935101
https://pubmed.ncbi.nlm.nih.gov/23935101
Autor:
Guillermo Calero, Hilary P. Stevenson, Jean-Pierre Vilardaga, Vanessa L. Wehbi, Timothy N. Feinstein, Guillermo Romero
G protein-coupled receptors (GPCRs) participate in ubiquitous transmembrane signal transduction processes by activating heterotrimeric G proteins. In the current “canonical” model of GPCR signaling, arrestins terminate receptor signaling by impai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f272a6e8a79ad445af480f759c598ca
https://europepmc.org/articles/PMC3557057/
https://europepmc.org/articles/PMC3557057/
Autor:
Guy Kornberg, Vesna Rapić-Otrin, Bennett Van Houten, Arthur S. Levine, Hilary P. Stevenson, Ye Peng, Antonella Cusimano, Ian S. Brown, Qiangmin Zhang, Monica Calero, Satdarshan P.S. Monga, Henrik Spåhr, Jennifer Guerrero-Santoro, Guillermo Calero, Shelley Reynolds, Hugo Santamaria-Suarez, Filippo Pullara
Publikováno v:
Protein expression and purification. 87(2)
Expression of recombinant proteins in bacterial or eukaryotic systems often results in aggregation rendering them unavailable for biochemical or structural studies. Protein aggregation is a costly problem for biomedical research. It forces research l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63f40f438ab097a34e02fd30f68cfca6
https://pubmed.ncbi.nlm.nih.gov/23137940
https://pubmed.ncbi.nlm.nih.gov/23137940
Autor:
Kimberly Musa Specht, Hilary P. Stevenson, Courtney M. Alexander, Kyle H. Sheetz, Lilian T. Lamech, Dawn M. Walker, Lauren H. O’Connor
Publikováno v:
Current microbiology. 60(4)
Putative penicillin-binding proteins (PBPs) were identified in the genome of the Burkholderia cenocepacia strain J2315 based on homology to E. coli PBPs. The three sequences identified as homologs of E. coli PBP1a, BCAL2021, BCAL0274, and BCAM2632, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ab2ed50c3929f400fe3c49cb08f9f84
https://pubmed.ncbi.nlm.nih.gov/19924480
https://pubmed.ncbi.nlm.nih.gov/19924480
Autor:
Uwe Weierstall, John C. H. Spence, Rebekka M. Wachter, Nadia A. Zatsepin, Garrett Nelson, Katerina Dörner, Raymond G. Sierra, Hilary P. Stevenson, Jesse Coe, Bahige G. Abdallah, Thomas D. Grant, Fernanda Camacho-Alanis, Alexandra Ros, Guillermo Calero, Chelsie E. Conrad, Daniel James, Shatabdi Roy-Chowdhury, Petra Fromme
Publikováno v:
Structural Dynamics, Vol 2, Iss 4, Pp 041719-041719-14 (2015)
Structural Dynamics
Structural Dynamics
The advent and application of the X-ray free-electron laser (XFEL) has uncovered the structures of proteins that could not previously be solved using traditional crystallography. While this new technology is powerful, optimization of the process is s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48424bdf4145bd455e67c7e9facb8ac9
https://doi.org/10.1063/1.4928688
https://doi.org/10.1063/1.4928688