Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Hilary M. Staples"'
Autor:
Fatai S. Oladunni, Jun-Gyu Park, Paula A. Pino, Olga Gonzalez, Anwari Akhter, Anna Allué-Guardia, Angélica Olmo-Fontánez, Shalini Gautam, Andreu Garcia-Vilanova, Chengjin Ye, Kevin Chiem, Colwyn Headley, Varun Dwivedi, Laura M. Parodi, Kendra J. Alfson, Hilary M. Staples, Alyssa Schami, Juan I. Garcia, Alison Whigham, Roy Neal Platt, Michal Gazi, Jesse Martinez, Colin Chuba, Stephanie Earley, Oscar H. Rodriguez, Stephanie Davis Mdaki, Katrina N. Kavelish, Renee Escalona, Cory R. A. Hallam, Corbett Christie, Jean L. Patterson, Tim J. C. Anderson, Ricardo Carrion, Edward J. Dick, Shannan Hall-Ursone, Larry S. Schlesinger, Xavier Alvarez, Deepak Kaushal, Luis D. Giavedoni, Joanne Turner, Luis Martinez-Sobrido, Jordi B. Torrelles
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
Here, the authors characterize tissue-level SARS-CoV-2 infection and pathogenesis in transgenic mice expressing human angiotensin converting enzyme 2 (hACE2) by the human cytokeratin 18 promoter (K18-hACE2) and show that infection induces lethality,
Externí odkaz:
https://doaj.org/article/36d6d32972464a4aafa1c9bc19844493
Autor:
Kendra J. Alfson, Yenny Goez-Gazi, Michal Gazi, Ying-Liang Chou, Nancy A. Niemuth, Marc E. Mattix, Hilary M. Staples, Benjamin Klaffke, Gloria F. Rodriguez, Carmen Bartley, Anysha Ticer, Elizabeth A. Clemmons, John W. Dutton, Anthony Griffiths, Gabe T. Meister, Daniel C. Sanford, Chris M. Cirimotich, Ricardo Carrion
Publikováno v:
Vaccines, Vol 10, Iss 8, p 1314 (2022)
Marburg virus (MARV) is a filovirus that can infect humans and nonhuman primates (NHPs), causing severe disease and death. Of the filoviruses, Ebola virus (EBOV) has been the primary target for vaccine and therapeutic development. However, MARV has a
Externí odkaz:
https://doaj.org/article/21c882aa05dc43e9936872174f3053a7
Publikováno v:
Stem Cell Reports
Coronavirus disease 2019 (COVID-19) patients have manifested a variety of neurological complications, and there is still much to reveal regarding the neurotropism of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Human stem cell-derive
Autor:
Min Ni, Anbo Zhou, Tammy Taylor, Mark G. Lewis, Anthony L. Cook, Maciel Porto, Olga Gonzalez, Neil Stahl, Adelekan Oyejide, Laurent Pessaint, Dharani Ajithdoss, John Dutton, Jack Greenhouse, Kendra J. Alfson, Edward J. Dick, Kathryn Lanza, Richard Copin, Christos A. Kyratsous, Bret J Musser, Kusha Mohammadi, Ricardo Carrion, Vaneesha Ali, Elizabeth Clemmons, Michal Gazi, George D. Yancopoulos, Nicole Negron, Hilary M. Staples, Hanne Leth Andersen, Gurinder S. Atwal, Alina Baum, Andrew J. Murphy, Renita Brown, Yenny Goez-Gazi, Yi Wei, Carmen Bartley, Benjamin Klaffke
Publikováno v:
Science
Science (New York, N.y.)
Science (New York, N.y.)
A beneficial cocktail Since the start of the coronavirus disease 2019 (COVID-19) pandemic, considerable effort has gone into generating and characterizing neutralizing antibodies that could be used as therapeutics. Studies in humanized mice and conva
Autor:
M. Gordon Joyce, Hannah A. D. King, Ines Elakhal-Naouar, Aslaa Ahmed, Kristina K. Peachman, Camila Macedo Cincotta, Caroline Subra, Rita E. Chen, Paul V. Thomas, Wei-Hung Chen, Rajeshwer S. Sankhala, Agnes Hajduczki, Elizabeth J. Martinez, Caroline E. Peterson, William C. Chang, Misook Choe, Clayton Smith, Parker J. Lee, Jarrett A. Headley, Mekdi G. Taddese, Hanne A. Elyard, Anthony Cook, Alexander Anderson, Kathryn McGuckin Wuertz, Ming Dong, Isabella Swafford, James Brett Case, Jeffrey R. Currier, Kerri G. Lal, Sebastian Molnar, Manoj S. Nair, Vincent Dussupt, Sharon P. Daye, Xiankun Zeng, Erica K. Barkei, Hilary M. Staples, Kendra Alfson, Ricardo Carrion, Shelly J. Krebs, Dominic Paquin-Proulx, Nicos Karasavva, Victoria R. Polonis, Linda L. Jagodzinski, Mihret F. Amare, Sandhya Vasan, Paul T. Scott, Yaoxing Huang, David D. Ho, Natalia de Val, Michael S. Diamond, Mark G. Lewis, Mangala Rao, Gary R. Matyas, Gregory D. Gromowski, Sheila A. Peel, Nelson L. Michael, Diane L. Bolton, Kayvon Modjarrad
Publikováno v:
Science translational medicine. 14(632)
The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants stresses the continued need for next-generation vaccines that confer broad protection against coronavirus disease 2019. We developed and evaluated an adjuvanted SA
Autor:
Lucy A Ward, Aysegul Nalca, Ricardo Carrion, Trevor Brasel, Arthur J. Goff, Hilary M. Staples, Alisha Rajbhandari, Margaret L. Pitt, Andrew Kocsis, John Trefry, Anthony Griffiths, Jason E. Comer, Cheryl A. Triplett, Nancy A. Niemuth, Clint Florence, Kendra J. Alfson, Dawn Fallacara, Amy C. Shurtleff, Shane Massey, Jake Lowry, Michael P. Fay, Sanjay M. Tamrakar, Yenny Goez-Gazi, Jeanon N. Smith, Sara C. Johnston
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 7, p e0252874 (2021)
PLoS ONE, Vol 16, Iss 7, p e0252874 (2021)
Filoviruses (Family Filoviridae genera Ebolavirus and Marburgvirus) are negative-stranded RNA viruses that cause severe health effects in humans and non-human primates, including death. Except in outbreak settings, vaccines and other medical counterm
Autor:
Kayvon Modjarrad, Aslaa Ahmed, Wei-Hung Chen, Mihret F. Amare, Vincent Dussupt, Elizabeth J. Martinez, Kendra J. Alfson, Rajeshwer S. Sankhala, Misook Choe, Jarrett A. Headley, Hilary M. Staples, Caroline E. Peterson, Xiankun Zeng, Natalia de Val, Mark G. Lewis, Paul T. Scott, Caroline Subra, Ricardo Carrion, M. Gordon Joyce, Sheila A. Peel, Kerri G. Lal, Sebastian Molnar, Ming Dong, James Brett Case, Anthony L. Cook, Rita E. Chen, David D. Ho, Agnes Hajduczki, Mangala Rao, Isabella Swafford, Dominic Paquin-Proulx, Camila Macedo Cincotta, Yaoxing Huang, Kathryn McGuckin Wuertz, Nicos Karasavvas, Shelly J. Krebs, Sharon P. Daye, Clayton A. Smith, Gary R. Matyas, Manoj S. Nair, Jeffrey R. Currier, Hanne A. Elyard, Nelson L. Michael, Ines Lakhal-Naouar, Michael S. Diamond, Erica K. Barkei, Diane L. Bolton, Sandhya Vasan, Linda L. Jagodzinski, Victoria R. Polonis, Gregory D. Gromowski, Alexander R. A. Anderson, Holly R. Hack, Hannah A.D. King, Paul V. Thomas, Kristina K. Peachman, William C. Chang
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
bioRxiv
bioRxiv
Significance The emergence of SARS-CoV-2 variants of concern (VOCs) that reduce the efficacy of current COVID-19 vaccines is a major threat to pandemic control. We evaluate a SARS-CoV-2 spike receptor-binding domain ferritin nanoparticle protein vacc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e04c0ddd418f55c7db5df557222ec1b
https://doi.org/10.1101/2021.04.09.439166
https://doi.org/10.1101/2021.04.09.439166
Autor:
Rajeshwer S. Sankhala, Caroline Subra, Sheila A. Peel, David D. Ho, Mangala Rao, Kathryn McGuckin-Wuertz, Rita E. Chen, Camila Macedo Cincotta, Parker J. Lee, Xiankun Zeng, Kerri G. Lal, Clayton Smith, Sebastian Molnar, Ming Dong, Michael Gordon Joyce, Erica K. Barkei, Hilary M. Staples, Natalia de Val, Diane L. Bolton, Michael S. Diamond, Kendra J. Alfson, Sharon P. Daye, Gregory D. Gromowski, Gary R. Matyas, Elizabeth J. Martinez, Vincent Dussupt, Paul T. Scott, Alexander R. A. Anderson, Linda L. Jagodzinski, Nicos Karasavva, Mekdi G. Taddese, Agnes Hajduczki, Dominic Paquin-Proulx, Kristina K. Peachman, James B. Case, Mihret F. Amare, Misook Choe, Isabella Swafford, William C. Chang, Kayvon Modjarrad, Anthony L. Cook, Hannah A.D. King, Hanne A. Elyard, Nelson L. Michael, Paul V. Thomas, Jarrett A. Headley, Caroline E. Peterson, Manoj S. Nair, Ines Elakhal Naouar, Ricardo Carrion, Shelly J. Krebs, Yaoxing Huang, Victoria R. Polonis, Jeffrey R. Currier, Mark G. Lewis, Sandhya Vasan, Aslaa Ahmed, Wei-Hung Chen
Publikováno v:
bioRxiv
The emergence of novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants stresses the continued need for next-generation vaccines that confer broad protection against coronavirus disease 2019 (COVID-19). We developed and evaluated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a439c01a26464a027ce247309bfb966
https://doi.org/10.1101/2021.03.24.436523
https://doi.org/10.1101/2021.03.24.436523
Autor:
George D. Yancopoulos, Yi Zhou, Christos A. Kyratsous, Shane McCarthy, Stephanie Giordano, Ricardo Carrion, Yi Wei, Newton Chan, Kristen E. Pascal, Benjamin O. Fulton, Kei Saotome, Joyce Chiu, Neil Stahl, Selin Somersan Karakaya, Leah Lipsich, Nicole Negron, Sara Hamon, Thomas Norton, David M. Weinreich, Annabel Romero Hernandez, Andrea T. Hooper, Sumathi Sivapalasingam, Richard Copin, Kathryn Lanza, Elzbieta Wloga, Andrew J. Murphy, Gurinder S. Atwal, Gary Herman, Matthew C. Franklin, Hilary M. Staples, Kendra J. Alfson, Min Ni, Shazia Ali, Alina Baum, Anbo Zhou, Jennifer D. Hamilton, Angel Coppola
SummaryMonoclonal antibodies against SARS-CoV-2 are a clinically validated therapeutic option against COVID-19. As rapidly emerging virus mutants are becoming the next major concern in the fight against the global pandemic, it is imperative that thes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::80aaebb4607c4f6f27a4048a22ff7262
https://doi.org/10.1101/2021.03.10.434834
https://doi.org/10.1101/2021.03.10.434834
Autor:
Patrick T Keiser, Anthony Griffiths, Marc Mattix, Chris M. Cirimotich, Kendra J. Alfson, Hilary M. Staples, Benjamin Klaffke, Kaylee Stanfield, Michal Gazi, Nancy A. Niemuth, Priscilla Escareno, Anysha Ticer, Yenny Goez-Gazi, Gabe T. Meister, Ricardo Carrion, Ying-Liang Chou
Publikováno v:
Microorganisms, Vol 9, Iss 489, p 489 (2021)
Microorganisms
Volume 9
Issue 3
Microorganisms
Volume 9
Issue 3
Ebola virus (EBOV) is a negative-sense RNA virus that can infect humans and nonhuman primates with severe health consequences. Development of countermeasures requires a thorough understanding of the interaction between host and pathogen, and the cour