Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Hilary J. Longhurst"'
Autor:
Stephen D. Betschel, Teresa Caballero, Douglas H. Jones, Hilary J. Longhurst, Michael Manning, Sally van Kooten, Markus Heckmann, Sherry Danese, Ledia Goga, Autumn Ford Burnette
Publikováno v:
Allergy, Asthma & Clinical Immunology, Vol 20, Iss 1, Pp 1-8 (2024)
Abstract Background Hereditary angioedema (HAE) is characterized by debilitating attacks of tissue swelling in various locations. While guidelines recommend the importance of early on-demand treatment, recent data indicate that many patients delay or
Externí odkaz:
https://doaj.org/article/f62f55aabf8648baa2fd7885c10d87e1
Autor:
Anna Valerieva, Hilary J. Longhurst
Publikováno v:
Frontiers in Allergy, Vol 3 (2022)
Hereditary angioedema (HAE) is a rare disease caused by mutations in the SERPING1 gene. This results in deficient or dysfunctional C1 esterase inhibitor (C1-INH) and affects multiple proteases involved in the complement, contact-system, coagulation,
Externí odkaz:
https://doaj.org/article/1ab09d59c51f46458e373cc930b9aecc
Autor:
Konrad Bork, John T. Anderson, Teresa Caballero, Timothy Craig, Douglas T. Johnston, H. Henry Li, Hilary J. Longhurst, Cristine Radojicic, Marc A. Riedl
Publikováno v:
Allergy, Asthma & Clinical Immunology, Vol 17, Iss 1, Pp 1-14 (2021)
Abstract Background Hereditary angioedema (HAE) is a rare disease characterized by unpredictable, potentially life-threatening attacks, resulting in significant physical and emotional burdens for patients and families. To optimize care for patients w
Externí odkaz:
https://doaj.org/article/852737c8b7524b67a4607b838b668854
Publikováno v:
Frontiers in Medicine, Vol 8 (2021)
Pulmonary fibrosis (PF) is a serious lung disease which can result from known genetic or environmental exposures but is more commonly idiopathic (IPF). In familial PF (FPF), the majority of identified causal genes play key roles in the maintenance of
Externí odkaz:
https://doaj.org/article/4131ac2dddd0479e9813a5de4c67ebbf
Autor:
H. Henry Li, Bruce Zuraw, Hilary J. Longhurst, Marco Cicardi, Konrad Bork, James Baker, William Lumry, Jonathan Bernstein, Michael Manning, Donald Levy, Marc A. Riedl, Henrike Feuersenger, Subhransu Prusty, Ingo Pragst, Thomas Machnig, Timothy Craig, for the COMPACT Investigators
Publikováno v:
Allergy, Asthma & Clinical Immunology, Vol 15, Iss 1, Pp 1-8 (2019)
Abstract Background Hereditary angioedema (HAE) is a debilitating disorder resulting from C1-esterase inhibitor (C1-INH) deficiency. In the COMPACT phase 3 study the prophylactic use of a subcutaneous C1 inhibitor (C1-INH [SC], HAEGARDA®, CSL Behrin
Externí odkaz:
https://doaj.org/article/46a5a0e153774c4bad9afb1f9a9948a5
Autor:
Anette Bygum, Teresa Caballero, Anete S. Grumach, Hilary J. Longhurst, Laurence Bouillet, Werner Aberer, Andrea Zanichelli, Jaco Botha, Irmgard Andresen, Marcus Maurer, for the IOS Study Group
Publikováno v:
Clinical and Translational Allergy, Vol 9, Iss 1, Pp 1-8 (2019)
Abstract Background Hereditary angioedema with C1 inhibitor deficiency (C1-INH-HAE) is characterized by recurrent swelling in subcutaneous or submucosal tissues. Symptoms often begin by age 5–11 years and worsen during puberty, but attacks can occu
Externí odkaz:
https://doaj.org/article/72f62a8e376a440c91f20ca5f1c41d12
Autor:
Andrea Zanichelli, Markus Magerl, Hilary J. Longhurst, Werner Aberer, Teresa Caballero, Laurence Bouillet, Anette Bygum, Anete S. Grumach, Jaco Botha, Irmgard Andresen, Marcus Maurer, the IOS Study Group
Publikováno v:
Clinical and Translational Allergy, Vol 8, Iss 1, Pp 1-5 (2018)
Abstract The objective of this analysis was to evaluate the change over time in age at first symptoms, age at diagnosis, and delay in diagnosis using data from the Icatibant Outcome Survey (IOS). Patients with a diagnosis of C1-INH-HAE who were born
Externí odkaz:
https://doaj.org/article/3c9276941ce64034a53aca00eb6720c0
Autor:
Hilary J. Longhurst, John Dempster, Lorena Lorenzo, Matthew Buckland, Sofia Grigoriadou, Christine Symons, Claire Bethune, Vincent Fabien, Catherine Bangs, Tomaz Garcez
Publikováno v:
Allergy, Asthma & Clinical Immunology, Vol 14, Iss 1, Pp 1-11 (2018)
Abstract Background Hereditary angioedema (HAE) is a potentially life-threatening, bradykinin-mediated disease, often misdiagnosed and under-treated, with long diagnostic delays. There are limited real-world data on best-practice management of HAE in
Externí odkaz:
https://doaj.org/article/4de5c34119a84c76a1d7d518f7d3d43d
Autor:
Teresa Caballero, Andrea Zanichelli, Werner Aberer, Marcus Maurer, Hilary J. Longhurst, Laurence Bouillet, Irmgard Andresen, the IOS Study Group
Publikováno v:
Clinical and Translational Allergy, Vol 8, Iss 1, Pp 1-10 (2018)
Abstract Background Icatibant is a bradykinin B2-receptor antagonist used for the treatment of hereditary angioedema attacks resulting from C1-inhibitor deficiency. Treatment is not adjusted by body weight however the impact of body mass index (BMI)
Externí odkaz:
https://doaj.org/article/8353b2779ad441c2b831554a2b29079a
Autor:
Marc A. Riedl, Jonathan A. Bernstein, Timothy Craig, Aleena Banerji, Markus Magerl, Marco Cicardi, Hilary J. Longhurst, Mustafa M. Shennak, William H. Yang, Jennifer Schranz, Jovanna Baptista, Paula J. Busse
Publikováno v:
Clinical and Translational Allergy, Vol 7, Iss 1, Pp 1-10 (2017)
Abstract Background Hereditary angioedema (HAE) is characterized by recurrent attacks of subcutaneous or submucosal edema. Attacks are unpredictable, debilitating, and have a significant impact on quality of life. Patients may be prescribed prophylac
Externí odkaz:
https://doaj.org/article/84360846dc2048d9b0686a042712b6e1