Výsledky vyhledávání - "Hilary Faust"

Collateral damage: necroptosis in the development of lung injury

Autor: Hilary Faust, Nilam S. Mangalmurti

Publikováno v: Am J Physiol Lung Cell Mol Physiol

Cell death is increasingly recognized as a driving factor in the development of acute lung injury. Necroptosis, an immunogenic regulated cell death program important in innate immunity, has been implicated in the development of lung injury in a diver

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b88f9af3f26ee6a7bee01c9faeb1e3e3
https://doi.org/10.1152/ajplung.00065.2019

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Regional citrate and systemic heparin are adequate to maintain filter half-life for COVID-19 patients on continuous renal replacement therapy

Autor: Cassandra Chiao, Hilary Faust, Tripti Singh

Publikováno v: Seminars in dialysis. 35(4)

The aim of our study is to compare clotting of CRRT filters in patients with COVID-19-associated AKI versus septic shock-associated AKI.Retrospective study of adult ICU patients with COVID-19 compared to those with septic shock admitted to a tertiary

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::777f03688f1528070190b467ce820491
https://pubmed.ncbi.nlm.nih.gov/35141966

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RAGE interacts with the necroptotic protein RIPK3 and mediates transfusion-induced danger signal release

Autor: Nilam S. Mangalmurti, Meghan J. Hotz, Danielle Qing, Lk Metthew Lam, Hilary Faust

Publikováno v: Vox Sang

RBC transfusion is associated with increased morbidity and mortality in critically ill patients. Endothelial cell necroptosis and subsequent damage-associated molecular pattern (DAMP) release has been identified as a mechanism of injury following RBC

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da91ca316473ef36b587a3d7954824f7
https://europepmc.org/articles/PMC8215843/

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Plasma receptor interacting protein kinase-3 levels are associated with acute respiratory distress syndrome in sepsis and trauma: a cohort study

Autor: Daniel N. Holena, Caroline A. G. Ittner, David Fitzgerald, Meghan J. Hotz, Jason D. Christie, Peggy Zhang, Wei Yang, Paul N. Lanken, John P. Reilly, Nilam S. Mangalmurti, Hilary Faust, Michael G.S. Shashaty, Brian J. Anderson, Nuala J. Meyer, Caitlin M. Forker

Publikováno v: Critical Care
Critical Care, Vol 23, Iss 1, Pp 1-11 (2019)

Background Necroptosis, a form of programmed cell death mediated by receptor interacting serine/threonine-protein kinase-3 (RIPK3), is implicated in murine models of acute respiratory distress syndrome (ARDS). We hypothesized that plasma RIPK3 concen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad6f6a0f05b0e27d3e5d2b4266cadbec
http://europepmc.org/articles/PMC6599265

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Plasma Mitochondrial DNA Levels Are Associated With ARDS in Trauma and Sepsis Patients

Autor: Nuala J. Meyer, Hilary Faust, Caitlyn M. Forker, Nilam S. Mangalmurti, Paul N. Lanken, Caroline A. G. Ittner, Jason D. Christie, Michael G.S. Shashaty, Brian J. Anderson, Benjamin A. Weaver, John P. Reilly, Daniel N. Holena, Peggy Zhang

Publikováno v: Chest

Background Critically ill patients who develop ARDS have substantial associated morbidity and mortality. Circulating mitochondrial DNA (mtDNA) released during critical illness causes endothelial dysfunction and lung injury in experimental models. Thi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b8e9441386ef123b9112a33e9d2808a
https://pubmed.ncbi.nlm.nih.gov/31622590

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Thromboelastography to Detect Hypercoagulability and Reduced Fibrinolysis in Coronavirus Disease 2019 Acute Respiratory Distress Syndrome Patients

Autor: Samir Sultan, Moniba Nazeef, Hilary Faust, Timothy Rowe, Pierre Kory, Corey J. Sadd

Publikováno v: Critical Care Explorations

Supplemental Digital Content is available in the text.
Objectives: Microvascular thrombosis contributes to acute respiratory distress syndrome pathophysiology and has been demonstrated in coronavirus disease 2019-associated acute respiratory dis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a769dfc84e98fcbfe57f839125bc22c
https://doi.org/10.1097/cce.0000000000000192

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