Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Hilary A. Weismiller"'
Autor:
George Devitt, William Rice, Caitlin Commins, Anna Crisford, Hilary A. Weismiller, Martin Margittai, Zhanyun Fan, Sumeet Mahajan, Bradley T. Hyman, Amritpal Mudher
Publikováno v:
RSC Advances
Tauopathies are a group of disorders in which the deposition of abnormally folded tau protein accompanies neurodegeneration. The development of methods for detection and classification of pathological changes in protein conformation are desirable for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3695f43eefe31a9c010591607d5fc7c
https://eprints.soton.ac.uk/447276/
https://eprints.soton.ac.uk/447276/
AB42 and polyamines: Elucidating a potential mechanism of amyloid‐mediated apoptosis and aggregation
Autor:
Austin Johnson, Ann-Charlotte Granholm, Carrie Hicks, Daniel A. Linseman, Luis F. Hernandez, Aurélie Ledreux, Daniel Paredes, Hilary A. Weismiller, Pablo Caviedes, Martin Margittai, David Patterson, Alexandra A. Sandberg, Stephanie Melgar, Sebastian D. L. Harvey, Yan Qin, Dylan H Fudge, Guido N. Vacano
Publikováno v:
Alzheimer's & Dementia. 16
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::355c425b6368985f42f83fe3e0f0b1aa
https://doi.org/10.1002/alz.039915
https://doi.org/10.1002/alz.039915
Publikováno v:
The Journal of Biological Chemistry
Oxidative stress has been implicated in the pathogenesis and progression of several tauopathies, including Alzheimer's disease. The deposition of fibrillar inclusions made of tau protein is one of the pathological hallmarks of these disorders. Althou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3bdb298e5ea560472264dfd2473cec1
https://doi.org/10.1016/j.jbc.2021.101021
https://doi.org/10.1016/j.jbc.2021.101021
Autor:
Hilary A. Weismiller, Gareth R. Eaton, Virginia Meyer, Sandra S. Eaton, Michael R. Holden, Martin Margittai
Publikováno v:
The Journal of Biological Chemistry
Tau fibrils are pathological aggregates that can transfer between neurons and then recruit soluble Tau monomers by template-assisted conversion. The propagation of different fibril polymorphs is thought to be a contributing factor to phenotypic diver
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abf0822731f181180c2ab11b9aa50649
https://doi.org/10.1074/jbc.m116.715557
https://doi.org/10.1074/jbc.m116.715557
Autor:
Martin Margittai, Guanghong Wei, Hilary A. Weismiller, Buyong Ma, Ruth Nussinov, Rachel Murphy
Publikováno v:
The Journal of biological chemistry. 293(45)
The intracellular deposition of fibrils composed of the microtubule-associated protein Tau is a characteristic feature of Alzheimer's disease (AD) and other fatal neurodegenerative disorders collectively known as tauopathies. Short Tau fibrils spread
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::364ed6478afc0506e773cc1e1acc51df
https://pubmed.ncbi.nlm.nih.gov/30242125
https://pubmed.ncbi.nlm.nih.gov/30242125
Autor:
Hilary A. Weismiller, Sandra S. Eaton, Joseph P. Y. Kao, Richard W. Quine, Gareth R. Eaton, Gerald M. Rosen, George A. Rinard, Hanan Elajaili, Joshua R. Biller, Mark Tseitlin
Publikováno v:
Journal of magnetic resonance (San Diego, Calif. : 1997). 242
Projections for 2D spectral-spatial images were obtained by continuous wave and rapid-scan electron paramagnetic resonance using a bimodal cross-loop resonator at 251 MHz. The phantom consisted of three 4 mm tubes containing different 15N,2H-substitu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::212a5ade5812069b89bd304874954f4e
https://pubmed.ncbi.nlm.nih.gov/24650729
https://pubmed.ncbi.nlm.nih.gov/24650729