Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Hilary A, Schenck"'
Autor:
James D. Anderson, W. Nathaniel Brennen, Hilary A. Schenck, Alison M. Walls, Robert A. Sikes, Milton L. Brown, Indrani Choudhury-Mukherjee
Publikováno v:
Clinical prostate cancer. 2(3)
The early detection and treatment of prostate cancer have increased survival and improved clinical outcomes. The nature of the disease and pathologic understaging result in a high proportion of patients developing locally recurrent disease or distant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6062c5b2a1d0fe355326d7c563194c86
https://pubmed.ncbi.nlm.nih.gov/15040864
https://pubmed.ncbi.nlm.nih.gov/15040864
Autor:
James D, Anderson, Todd P, Hansen, Paul W, Lenkowski, Alison M, Walls, Indrani M, Choudhury, Hilary A, Schenck, Mati, Friehling, Genevieve M, Höll, Manoj K, Patel, Robert A, Sikes, Milton L, Brown
Publikováno v:
Molecular cancer therapeutics. 2(11)
The recent discovery of sodium (Na(+)) channel expression in human prostate cancer (PCa) cells led us to investigate the potential use of neuronal Na(+) channel blockers as inhibitors of PCa cells. Our initial studies discovered two classes of Na(+)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::166c95f10d8339ddbbe4fe118679c1f4
https://pubmed.ncbi.nlm.nih.gov/14617788
https://pubmed.ncbi.nlm.nih.gov/14617788
Autor:
Indrani Choudhury-Mukherjee, James P. Stables, Milton L. Brown, Paul W. Lenkowski, Hilary A. Schenck, Seong-Hoon Ko, Manoj K. Patel
Publikováno v:
Bioorganicmedicinal chemistry. 12(5)
Themisone, also known as Atrolactamide, was found, in the 1950s, to be a very potent anticonvulsant. It was hypothesized that the -CF3 substitution would maintain the anticonvulsant activity. Anticonvulsant testing of our novel compounds by the Natio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4243b3c5978a5d89ec9d1a8aa9a0c4c4
https://pubmed.ncbi.nlm.nih.gov/14980611
https://pubmed.ncbi.nlm.nih.gov/14980611
Autor:
Indrani Choudhury-Mukherjee, Milton L. Brown, Jeffrey F. Ellena, Jaideep Kapur, Thomas N. Pajewski, Sylvia Cechova, David S. Cafiso, Hilary A. Schenck
Publikováno v:
Journal of medicinal chemistry. 46(12)
We have recently discovered a novel class of compounds that have oral general anesthetic activity, potent anticonvulsant activity, and minimal hemodynamic effects. The 3,3,3-trifluoro-2-hydroxy-2-phenyl-propionamide (1) demonstrated potent ability to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9a0be2447b0137de5cdb9e029756415
https://pubmed.ncbi.nlm.nih.gov/12773053
https://pubmed.ncbi.nlm.nih.gov/12773053