An integrative methodology based on protein-protein interaction networks for identification and functional annotation of disease-relevant genes applied to channelopathies

Autor: Eduardo Ros, Milagros Marín, Hilario Ramírez-Rodrigo, Francisco J. Esteban, María José Sáez-Lara

Publikováno v: BMC Bioinformatics, Vol 20, Iss 1, Pp 1-13 (2019)
BMC Bioinformatics
Digibug. Repositorio Institucional de la Universidad de Granada
instname

Biologically data-driven networks have become powerful analytical tools that handle massive, heterogeneous datasets generated from biomedical fields. Protein-protein interaction networks can identify the most relevant structures directly tied to biol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa17eeb226277e3a0f66b37e1b7c80d0
http://hdl.handle.net/10481/58271

Characterization of a new operon, as-48EFGH, from the as-48 gene cluster involved in immunity to enterocin AS-48

Autor: Manuel Martínez-Bueno, Mercedes Maqueda, Matilde Fernández, Marta Díaz, Eva Valdivia, Hilario Ramírez-Rodrigo, Andrés Santos Soler-González

Publikováno v: Applied and environmental microbiology. 69(2)

Enterocin AS-48 is a cyclic peptide produced by Enterococcus faecalis S-48 whose genetic determinants have been identified in the conjugative plasmid pMB2. A region of 7.8 kb, carrying the minimum information required for production of and immunity a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f389d1025243fa2b7de4a0a97b6c0c5
https://pubmed.ncbi.nlm.nih.gov/12571051