Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Hilal Bhat"'
Autor:
Denis M. Schewe, Fotini Vogiatzi, Ira A. Münnich, Tobias Zeller, Roland Windisch, Christian Wichmann, Kristina Müller, Hilal Bhat, Elisa Felix, Dimitrios Mougiakakos, Heiko Bruns, Lennart Lenk, Thomas Valerius, Andreas Humpe, Matthias Peipp, Christian Kellner
Publikováno v:
HemaSphere, Vol 8, Iss 2, Pp n/a-n/a (2024)
Abstract CD19‐directed immunotherapy has become a cornerstone in the therapy of B‐cell precursor acute lymphoblastic leukemia (BCP‐ALL). CD19‐directed cellular and antibody‐based therapeutics have entered therapy of primary and relapsed dis
Externí odkaz:
https://doaj.org/article/9fd66e3abc514ac88a3fe38bc7edfa67
Autor:
Lea Spory, Johannes Zimmermann, Michaela Vossen-Gajcy, Thomas Beder, Lorenz Bastian, Ameera Alsadeq, Dorothee Winterberg, Fotini Vogiatzi, Tim Wirbelauer, Hilal Bhat, Arndt Borkhardt, Sanil Bhatia, Martin Schrappe, Gunnar Cario, Denis M. Schewe, Lennart Lenk
Publikováno v:
HemaSphere, Vol 7, Iss 9, p e945 (2023)
Externí odkaz:
https://doaj.org/article/4121c3b59dfa474f93d735267a543fa8
Publikováno v:
Cellular Physiology and Biochemistry, Vol 56, Iss 4, Pp 340-352 (2022)
Externí odkaz:
https://doaj.org/article/6082c64deec9422abbf01be746a19e0d
Publikováno v:
Cellular Physiology and Biochemistry, Vol 55, Iss 6, Pp 726-738 (2021)
Externí odkaz:
https://doaj.org/article/2b1e5cba974542628bdbe3c82853a544
Lactic acidosis in diabetic ketoacidosis: A marker of severity or alternate substrate for metabolism
Autor:
Javaid Ahmad Bhat, Shariq Rashid Masoodi, Moomin Hussain Bhat, Hilal Bhat, Peerzada Ovais Ahmad, Mona Sood
Publikováno v:
Indian Journal of Endocrinology and Metabolism, Vol 25, Iss 1, Pp 59-66 (2021)
Purpose: The lactate level is being increasingly used as a marker of severity of illness and prognosis in multitude of critical conditions. However, its role in diabetic ketoacidosis (DKA) is not well defined. Aim: To determine the prevalence and cli
Externí odkaz:
https://doaj.org/article/b277ca82fbc24abeb117ab08341b2276
Autor:
Judith Lang, Patrick Bohn, Hilal Bhat, Holger Jastrow, Bernd Walkenfort, Feyza Cansiz, Julian Fink, Michael Bauer, Dominik Olszewski, Ana Ramos-Nascimento, Vikas Duhan, Sarah-Kim Friedrich, Katrin Anne Becker, Adalbert Krawczyk, Michael J. Edwards, Andreas Burchert, Magdalena Huber, Justa Friebus-Kardash, Joachim R. Göthert, Cornelia Hardt, Hans Christian Probst, Fabian Schumacher, Karl Köhrer, Burkhard Kleuser, Eduard B. Babiychuk, Beate Sodeik, Jürgen Seibel, Urs F. Greber, Philipp A. Lang, Erich Gulbins, Karl S. Lang
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Macrophages are critical in limiting replication of herpes simplex virus type 1 (HSV-1). Here the authors show how acid ceramidase and its enzymatic product sphingosine enable multivesicular bodies to function as an anti-viral mechanism.
Externí odkaz:
https://doaj.org/article/ce87beeac86246829e4b47c4ed971f39
Autor:
Vikas Duhan, Vishal Khairnar, Simo Kitanovski, Thamer A. Hamdan, Andrés D. Klein, Judith Lang, Murtaza Ali, Tom Adomati, Hilal Bhat, Sarah-Kim Friedrich, Fanghui Li, Philippe Krebs, Anthony H. Futerman, Marylyn M. Addo, Cornelia Hardt, Daniel Hoffmann, Philipp A. Lang, Karl S. Lang
Publikováno v:
Frontiers in Immunology, Vol 11 (2021)
Early and strong production of IFN-I by dendritic cells is important to control vesicular stomatitis virus (VSV), however mechanisms which explain this cell-type specific innate immune activation remain to be defined. Here, using a genome wide associ
Externí odkaz:
https://doaj.org/article/49106a4d1a9d447db837fc95b1d9fd9c
Autor:
Hilal Bhat, Gregor Zaun, Thamer A. Hamdan, Judith Lang, Tom Adomati, Rosa Schmitz, Sarah-Kim Friedrich, Michael Bergerhausen, Lamin B. Cham, Fanghui Li, Murtaza Ali, Fan Zhou, Vishal Khairnar, Vikas Duhan, Tim Brandenburg, Yara Maria Machlah, Maximilian Schiller, Arshia Berry, Haifeng Xu, Jörg Vollmer, Dieter Häussinger, Beatrice Thier, Aleksandra A. Pandyra, Dirk Schadendorf, Annette Paschen, Martin Schuler, Philipp A. Lang, Karl S. Lang
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Immune activation within the tumor microenvironment is one promising approach to induce tumor regression. Certain viruses including oncolytic viruses such as the herpes simplex virus (HSV) and non-oncolytic viruses such as the lymphocytic choriomenin
Externí odkaz:
https://doaj.org/article/75601dc4b0134284b6d488ec8fac6ac6
Autor:
Tom Adomati, Lamin B. Cham, Thamer A. Hamdan, Hilal Bhat, Vikas Duhan, Fanghui Li, Murtaza Ali, Elisabeth Lang, Anfei Huang, Eyad Naser, Vishal Khairnar, Sarah-Kim Friedrich, Judith Lang, Justa Friebus-Kardash, Michael Bergerhausen, Maximilian Schiller, Yara Maria Machlah, Florian Lang, Dieter Häussinger, Stanislav Ferencik, Cornelia Hardt, Philipp A. Lang, Karl S. Lang
Publikováno v:
Cell Reports, Vol 30, Iss 11, Pp 3671-3681.e5 (2020)
Summary: Infections can result in a temporarily restricted unresponsiveness of the innate immune response, thereby limiting pathogen control. Mechanisms of such unresponsiveness are well studied in lipopolysaccharide tolerance; however, whether mecha
Externí odkaz:
https://doaj.org/article/adb0a8a0b0c54307b1e06bb9c186cfaa
Autor:
Vishal Khairnar, Vikas Duhan, Ashwini M. Patil, Fan Zhou, Hilal Bhat, Christine Thoens, Piyush Sharma, Tom Adomati, Sarah-Kim Friendrich, Judith Bezgovsek, Janine D. Dreesen, Gunther Wennemuth, Astrid M. Westendorf, Gennadiy Zelinskyy, Ulf Dittmer, Cornelia Hardt, Jörg Timm, Joachim R. Göthert, Philipp A. Lang, Bernhard B. Singer, Karl S. Lang
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Chronic viral infections are frequently associated with the dysfunction of CD8+ T cells which includes loss of function and results in CD8+ T cell exhaustion. Here the authors show a role of CEACAM1 in promoting responsive CD8+ T cells in the context
Externí odkaz:
https://doaj.org/article/bede592b38dd44ccaefbb07e0a9f1236