Zobrazeno 1 - 10
of 286
pro vyhledávání: '"Hilal A Lashuel"'
Autor:
Hilal A Lashuel
Publikováno v:
eLife, Vol 9 (2020)
After two heart attacks in three years, an associate professor discusses the challenges of faculty life.
Externí odkaz:
https://doaj.org/article/244694b5afe64eb68da6e9d572a50554
Autor:
Galina Limorenko, Meltem Tatli, Rajasekhar Kolla, Sergey Nazarov, Marie-Theres Weil, David C. Schöndorf, Daniela Geist, Peter Reinhardt, Dagmar E. Ehrnhoefer, Henning Stahlberg, Laura Gasparini, Hilal A. Lashuel
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-4 (2024)
Externí odkaz:
https://doaj.org/article/d07236fa47e046cfa7e71aeb67ae1a08
Autor:
Abid Oueslati, Blaise Lovisa, John Perrin, Georges Wagnières, Hubert van den Bergh, Yanik Tardy, Hilal A Lashuel
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0140880 (2015)
Converging lines of evidence indicate that near-infrared light treatment, also known as photobiomodulation (PBM), may exert beneficial effects and protect against cellular toxicity and degeneration in several animal models of human pathologies, inclu
Externí odkaz:
https://doaj.org/article/1e8aee51ca414f93b927adcc3cf14648
Autor:
Melek Firat Altay, Senthil T. Kumar, Johannes Burtscher, Somanath Jagannath, Catherine Strand, Yasuo Miki, Laura Parkkinen, Janice L. Holton, Hilal A. Lashuel
Publikováno v:
npj Parkinson's Disease, Vol 9, Iss 1, Pp 1-21 (2023)
Abstract The abnormal aggregation and accumulation of alpha-synuclein (aSyn) in the brain is a defining hallmark of synucleinopathies. Various aSyn conformations and post-translationally modified forms accumulate in pathological inclusions and vary i
Externí odkaz:
https://doaj.org/article/75e3ac5b75ef4930b6ce1a22c6cbcc54
Autor:
Margot Fournier, Jérémie Vitte, Jérôme Garrigue, Dominique Langui, Jean-Philippe Dullin, Françoise Saurini, Naïma Hanoun, Fernando Perez-Diaz, Fabien Cornilleau, Chantal Joubert, Héctor Ardila-Osorio, Sabine Traver, René Duchateau, Cécile Goujet-Zalc, Katerina Paleologou, Hilal A Lashuel, Christian Haass, Charles Duyckaerts, Charles Cohen-Salmon, Philipp J Kahle, Michel Hamon, Alexis Brice, Olga Corti
Publikováno v:
PLoS ONE, Vol 4, Iss 8, p e6629 (2009)
In synucleinopathies, including Parkinson's disease, partially ubiquitylated alpha-synuclein species phosphorylated on serine 129 (P(S129)-alpha-synuclein) accumulate abnormally. Parkin, an ubiquitin-protein ligase that is dysfunctional in autosomal
Externí odkaz:
https://doaj.org/article/3b68bd1a5b804cd19da875320f51d756
Autor:
Fernando E Herrera, Alessandra Chesi, Katerina E Paleologou, Adrian Schmid, Adriana Munoz, Michele Vendruscolo, Stefano Gustincich, Hilal A Lashuel, Paolo Carloni
Publikováno v:
PLoS ONE, Vol 3, Iss 10, p e3394 (2008)
The interplay between dopamine and alpha-synuclein (AS) plays a central role in Parkinson's disease (PD). PD results primarily from a severe and selective devastation of dopaminergic neurons in substantia nigra pars compacta. The neuropathological ha
Externí odkaz:
https://doaj.org/article/7490c80dd22d4864a793806669576e2d
Autor:
Khalid A. Ibrahim, Kristin S. Grußmayer, Nathan Riguet, Lely Feletti, Hilal A. Lashuel, Aleksandra Radenovic
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-11 (2023)
Abstract Protein misfolding and aggregation play central roles in the pathogenesis of various neurodegenerative diseases (NDDs), including Huntington’s disease, which is caused by a genetic mutation in exon 1 of the Huntingtin protein (Httex1). The
Externí odkaz:
https://doaj.org/article/377d5977bf6544cea4a57377a3f9148c
Autor:
Galina Limorenko, Meltem Tatli, Rajasekhar Kolla, Sergey Nazarov, Marie-Theres Weil, David C. Schöndorf, Daniela Geist, Peter Reinhardt, Dagmar E. Ehrnhoefer, Henning Stahlberg, Laura Gasparini, Hilal A. Lashuel
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-21 (2023)
Abstract Tau protein fibrillization is implicated in the pathogenesis of several neurodegenerative diseases collectively known as Tauopathies. For decades, investigating Tau fibrillization in vitro has required the addition of polyanions or other co-
Externí odkaz:
https://doaj.org/article/4a93e56ba7444ef9af2e9994cee7c9f1
Autor:
Yogesh Singh, Christoph Trautwein, Joan Romani, Madhuri S. Salker, Peter H. Neckel, Isabel Fraccaroli, Mahkameh Abeditashi, Nils Woerner, Jakob Admard, Achal Dhariwal, Morten K. D. Dueholm, Karl-Herbert Schäfer, Florian Lang, Daniel E. Otzen, Hilal A. Lashuel, Olaf Riess, Nicolas Casadei
Publikováno v:
Molecular Neurodegeneration, Vol 18, Iss 1, Pp 1-28 (2023)
Abstract Background Braak’s hypothesis states that sporadic Parkinson’s disease (PD) follows a specific progression of pathology from the peripheral to the central nervous system, and this progression can be monitored by detecting the accumulatio
Externí odkaz:
https://doaj.org/article/a3d79a113d0147b78484a1d4a475b1f5
Autor:
Elena Losero, Somanath Jagannath, Maurizio Pezzoli, Valentin Goblot, Hossein Babashah, Hilal A. Lashuel, Christophe Galland, Niels Quack
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Monitoring neuronal activity with simultaneously high spatial and temporal resolution in living cell cultures is crucial to advance understanding of the development and functioning of our brain, and to gain further insights in the origin of
Externí odkaz:
https://doaj.org/article/b5d6101b026149549f16e4dce2057dcd