Výsledky vyhledávání - "Hilaire Yam Fung Cheung"

Akademický článek

Inhibition of Src but not Syk causes weak reversal of GPVI-mediated platelet aggregation measured by light transmission aggregometry

Autor: Hilaire Yam Fung Cheung, Luis A. Moran, Albert Sickmann, Johan W.M. Heemskerk, Ángel Garcia, Steve P. Watson

Publikováno v: Platelets, Vol 33, Iss 8, Pp 1293-1300 (2022)

Src tyrosine kinases and spleen tyrosine kinase (Syk) have recently been shown to contribute to sustained platelet aggregation on collagen under arterial shear. In the present study, we have investigated whether Src and Syk are required for aggregati

Externí odkaz: https://doaj.org/article/658911ff2f36451db5cf428008920244

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High-throughput assessment identifying major platelet Ca2+ entry pathways via tyrosine kinase-linked and G protein-coupled receptors

Autor: Hilaire Yam Fung Cheung, Jinmi Zou, Chukiat Tantiwong, Delia I. Fernandez, Jingnan Huang, Robert Ahrends, Mark Roest, Rachel Cavill, Jon Gibbins, Johan W.M. Heemskerk

Publikováno v: Cell Calcium, 112:102738. ELSEVIER SCI LTD

In platelets, elevated cytosolic Ca 2+ is a crucial second messenger, involved in most functional responses, including shape change, secretion, aggregation and procoagulant activity. The platelet Ca 2+ response consists of Ca 2+ mobilization from end

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc5efef8320806d0a973f4939130b681
https://cris.maastrichtuniversity.nl/en/publications/df4aa302-01ac-46d6-a4a5-b56776974b20

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