Zobrazeno 1 - 10
of 580
pro vyhledávání: '"Hilaire C"'
Autor:
Krinio Giannikou, Katie R. Martin, Ahmad G. Abdel-Azim, Kaila J. Pamir, Thomas R. Hougard, Shefali Bagwe, Yan Tang, Jeffrey P. MacKeigan, David J. Kwiatkowski, Elizabeth P. Henske, Hilaire C. Lam
Publikováno v:
Frontiers in Genetics, Vol 13 (2023)
Tuberous Sclerosis Complex (TSC) is caused by loss of function variants in either TSC1 or TSC2 and is characterized by broad phenotypic heterogeneity. Currently, there is limited knowledge regarding the role of the mitochondrial genome (mtDNA) in TSC
Externí odkaz:
https://doaj.org/article/7a16e35977df4b36bf8e5045581ebf3c
Autor:
Nicola Alesi, Elie W. Akl, Damir Khabibullin, Heng-Jia Liu, Anna S. Nidhiry, Emma R. Garner, Harilaos Filippakis, Hilaire C. Lam, Wei Shi, Srinivas R. Viswanathan, Manrico Morroni, Shawn M. Ferguson, Elizabeth P. Henske
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Tuberous sclerosis complex (TSC) is a multiorgan disease that can lead to hyperactive mTORC1 due to deficient TSC1 or TSC2 protein function. Here, the authors find that despite high mTORC1 activity, TFEB localizes to the nucleus and drives lysosomal
Externí odkaz:
https://doaj.org/article/ec225f1e3e484d6c80c74d6195d73b5c
Autor:
Li, P. J., Lee, J., Doornenbal, P., Chen, S., Wang, S., Obertelli, A., Chazono, Y., Holt, J. D., Hu, B. S., Ogata, K., Utsuno, Y., Yoshida, K., Achouri, N. L., Baba, H., Browne, F., Calvet, D., Château, F., Chiga, N., Corsi, A., Cortés, M. L., Delbart, A., Gheller, J-M., Giganon, A., Gillibert, A., Hilaire, C., Isobe, T., Kobayashi, T., Kubota, Y., Lapoux, V., Liu, H. N., Motobayashi, T., Murray, I., Otsu, H., Panin, V., Paul, N., Rodriguez, W., Sakurai, H., Sasano, M., Steppenbeck, D., Stuhl, L., Sun, Y. L., Togano, Y., Uesaka, T., Wimmer, K., Yoneda, K., Aktas, O., Aumann, T., Boretzky, K., Caesar, C., Chung, L. X., Flavigny, F., Franchoo, S., Gasparic, I., Gerst, R. -B., Gibelin, J., Hahn, K. I., Kahlbow, J., Kim, D., Koiwai, T., Kondo, Y., Körper, D., Koseoglou, P., Lehr, C., Linh, B. D., Lokotko, T., MacCormick, M., Miki, K., Moschner, K., Nakamura, T., Park, S. Y., Rossi, D., Sahin, E., Schindler, F., Simon, H., Söderström, P-A., Sohler, D., Takeuchi, S., Toernqvist, H., Tscheuschner, J., Vaquero, V., Wagner, V., Werner, V., Xu, X., Yamada, H., Yan, D., Yang, Z., Yasuda, M., Zanetti, L.
Publikováno v:
Phys. Lett. B, 855 (2024),138828
The calcium isotopes are an ideal system to investigate the evolution of shell structure and magic numbers. Although the properties of surface nucleons in calcium have been well studied, probing the structure of deeply bound nucleons remains a challe
Externí odkaz:
http://arxiv.org/abs/2407.04529
Autor:
Hyunwook Lee, Qinqin Fei, Adam Streicher, Wenjuan Zhang, Colleen Isabelle, Pragi Patel, Hilaire C. Lam, Antonio Arciniegas-Rubio, Miguel Pinilla-Vera, Diana P. Amador-Munoz, Diana Barragan-Bradford, Angelica Higuera-Moreno, Rachel K. Putman, Lynette M. Sholl, Elizabeth P. Henske, Christopher M. Bobba, Natalia Higuita-Castro, Emily M. Shalosky, R. Duncan Hite, John W. Christman, Samir N. Ghadiali, Rebecca M. Baron, Joshua A. Englert
Publikováno v:
JCI Insight, Vol 6, Iss 14 (2021)
The acute respiratory distress syndrome (ARDS) is a highly lethal condition that impairs lung function and causes respiratory failure. Mechanical ventilation (MV) maintains gas exchange in patients with ARDS but exposes lung cells to physical forces
Externí odkaz:
https://doaj.org/article/046048147d16480695cff473141c80c1
Autor:
Harilaos Filippakis, Amine Belaid, Brian Siroky, Constance Wu, Nicola Alesi, Thomas Hougard, Julie Nijmeh, Hilaire C. Lam, Elizabeth P. Henske
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)
Abstract Tuberous Sclerosis Complex (TSC), a rare genetic disorder with mechanistic target of rapamycin complex 1 (mTORC1) hyperactivation, is characterized by multi-organ hamartomatous benign tumors including brain, skin, kidney, and lung (Lymphangi
Externí odkaz:
https://doaj.org/article/65c5fa2a638943b98987048fb33e5747
Autor:
Chen, S., Browne, F., Doornenbal, P., Lee, J., Obertelli, A., Tsunoda, Y., Otsuka, T., Chazono, Y., Hagen, G., Holt, J. D., Jansen, G. R., Ogata, K., Shimizu, N., Utsuno, Y., Yoshida, K., Achouri, N. L., Baba, H., Calvet, D., Château, F., Chiga, N., Corsi, A., Cortés, M. L., Delbart, A., Gheller, J. -M., Giganon, A., Gillibert, A., Hilaire, C., Isobe, T., Kobayashi, T., Kubota, Y., Lapoux, V., Liu, H. N., Motobayashi, T., Murray, I., Otsu, H., Panin, V., Paul, N., Rodriguez, W., Sakurai, H., Sasano, M., Steppenbeck, D., Stuhl, L., Sun, Y. L., Togano, Y., Uesaka, T., Wimmer, K., Yoneda, K., Aktas, O., Aumann, T., Chung, L. X., Flavigny, F., Franchoo, S., Gasparic, I., Gerst, R. -B., Gibelin, J., Hahn, K. I., Kim, D., Koiwai, T., Kondo, Y., Koseoglou, P., Lehr, C., Linh, B. D., Lokotko, T., MacCormick, M., Moschner, K., Nakamura, T., Park, S. Y., Rossi, D., Sahin, E., Söderström, P. -A., Sohler, D., Takeuchi, S., Törnqvist, H., Vaquero, V., Wagner, V., Wang, S., Werner, V., Xu, X., Yamada, H., Yan, D., Yang, Z., Yasuda, M., Zanetti, L.
Publikováno v:
Phys. Lett. B 843 (2023) 138025
Gamma decays were observed in $^{56}$Ca and $^{58}$Ca following quasi-free one-proton knockout reactions from $^{57,59}$Sc beams at $\approx 200$ MeV/nucleon. For $^{56}$Ca, a $\gamma$ ray transition was measured to be 1456(12) keV, while for $^{58}$
Externí odkaz:
http://arxiv.org/abs/2307.07077
Autor:
Koiwai, T., Wimmer, K., Doornenbal, P., Obertelli, A., Barbieri, C., Duguet, T., Holt, J. D., Miyagi, T., Navrátil, P., Ogata, K., Shimizu, N., Somà, V., Utsuno, Y., Yoshida, K., Achouri, N. L., Baba, H., Browne, F., f, D. Calvet, Château, F., Chen, S., Chiga, N., Corsi, A., Cortés, M. L., Delbart, A., Gheller, J. -M., Giganon, A., Gillibert, A., Hilaire, C., Isobe, T., Kobayashi, T., Kubota, Y., Lapoux, V., Liu, H. N., Motobayashi, T., Murray, I., Otsu, H., Panin, V., Paul, N., Rodriguez, W., Sakurai, H., Sasano, M., Steppenbeck, D., Stuhl, L., Sun, Y. L., Togano, Y., Uesaka, T., Yoneda, K., Aktas, O., Aumann, T., Chung, L. X., Flavigny, F., Franchoo v, S., Gasparic, I., Gerst, R. -B., Gibelin, J., Hahn, K. I., Kim, D., Kondo, Y., Koseoglou, P., Lee, J., Lehr, C., Linh, B. D., Lokotko, T., MacCormick, M., Moschner, K., Nakamura, T., Park, S. Y., Rossi, D., Sahin, E., Söderström, P-A., Sohler, D., Takeuchi, S., Toernqvist, H., Vaquero, V., Wagner, V., Wang, S., Werner, V., Xu, X., Yamada, H., Yan, D., Yang, Z., Yasuda, M., Zanetti, L.
States in the $N=35$ and 37 isotopes $^{55,57}$Ca have been populated by direct proton-induced nucleon removal reactions from $^{56,58}$Sc and $^{56}$Ca beams at the RIBF. In addition, the $(p,2p)$ quasi-free single-proton removal reaction from $^{56
Externí odkaz:
http://arxiv.org/abs/2202.03050
Autor:
Linh, B. D., Corsi, A., Gillibert, A., Obertelli, A., Doornenbal, P., Barbieri, C., Chen, S., Chung, L. X., Duguet, T., Gómez-Ramos, M., Holt, J. D., Moro, A., Navrátil, P., Ogata, K., Phuc, N. T. T., Shimizu, N., Somà, V., Utsuno, Y., Achouri, N. L., Baba, H., Browne, F., Calvet, D., Château, F., Chiga, N., Cortés, M. L., Delbart, A., Gheller, J. -M., Giganon, A., Hilaire, C., Isobe, T., Kobayashi, T., Kubota, Y., Lapoux, V., Liu, H. N., Motobayashi, T., Murray, I., Otsu, H., Panin, V., Paul, N., Rodriguez, W., Sakurai, H., Sasano, M., Steppenbeck, D., Stuhl, L., Sun, Y. L., Togano, Y., Uesaka, T., Wimmer, K., Yoneda, K., Aktas, O., Aumann, T., Flavigny, F., Franchoo, S., Gašparić, I., Gerst, R. -B., Gibelin, J., Hahn, K. I., Khai, N. T., Kim, D., Koiwai, T., Kondo, Y., Koseoglou, P., Lee, J., Lehr, C., Lokotko, T., MacCormick, M., Moschner, K., Nakamura, T., Park, S. Y., Rossi, D., Sahin, E., Sohler, D., Söderström, P. -A., Takeuchi, S., Ton, N. D., Törnqvist, H., Vaquero, V., Wagner, V., Wang, H., Werner, V., Xu, X., Yamada, Y., Yan, D., Yang, Z., Yasuda, M., Zanetti, L.
A first gamma-ray study of 47,49Cl spectroscopy was performed at the Radioactive Isotope Beam Factory with 50Ar projectiles at 217 MeV/nucleon, impinging on the liquid hydrogen target of the MINOS device. Prompt de-excitation gamma-rays were measured
Externí odkaz:
http://arxiv.org/abs/2110.03284
Autor:
Cortés, M. L., Rodriguez, W., Doornenbal, P., Obertelli, A., Holt, J. D., Menéndez, J., Ogata, K., Schwenk, A., Shimizu, N., Simonis, J., Utsuno, Y., Yoshida, K., Achouri, L., Baba, H., Browne, F., Calvet, D., Château, F., Chen, S., Chiga, N., Corsi, A., Delbart, A., Gheller, J-M., Giganon, A., Gillibert, A., Hilaire, C., Isobe, T., Kobayashi, T., Kubota, Y., Lapoux, V., Liu, H. N., Motobayashi, T., Murray, I., Otsu, H., Panin, V., Paul, N., Sakurai, H., Sasano, M., Steppenbeck, D., Stuhl, L., Sun, Y. L., Togano, Y., Uesaka, T., Wimmer, K., Yoneda, K., Aktas, O., Aumann, T., Chung, L. X., Flavigny, F., Franchoo, S., Gašparić, I., Gerst, R. -B., Gibelin, J., Hahn, K. I., Kim, D., Koiwai, T., Kondo, Y., Koseoglou, P., Lee, J., Lehr, C., Linh, B. D., Lokotko, T., MacCormick, M., Moschner, K., Nakamura, T., Park, S. Y., Rossi, D., Sahin, E., Söderström, P. -A., Sohler, D., Takeuchi, S., Toernqvist, H., Vaquero, V., Wagner, V., Wang, S., Werner, V., Xu, X., Yamada, H., Yan, D., Yang, Z., Yasuda, M., Zanetti, L.
Publikováno v:
Phys. Rev. C 102, 064320 (2020)
Low-lying excited states in the $N=32$ isotope $^{50}$Ar were investigated by in-beam $\gamma$-ray spectroscopy following proton- and neutron-knockout, multi-nucleon removal, and proton inelastic scattering at the RIKEN Radioactive Isotope Beam Facto
Externí odkaz:
http://arxiv.org/abs/2011.10786
Autor:
Cortés, M. L., Rodriguez, W., Doornenbal, P., Obertelli, A., Holt, J. D., Lenzi, S. M., Menéndez, J., Nowacki, F., Ogata, K., Poves, A., Rodríguez, T. R., Schwenk, A., Simonis, J., Stroberg, S. R., Yoshida, K., Achouri, L., Baba, H., Browne, F., Calvet, D., Château, F., Chen, S., Chiga, N., Corsi, A., Delbart, A., Gheller, J-M., Giganon, A., Gillibert, A., Hilaire, C., Isobe, T., Kobayashi, T., Kubota, Y., Lapoux, V., Liu, H. N., Motobayashi, T., Murray, I., Otsu, H., Panin, V., Paul, N., Sakurai, H., Sasano, M., Steppenbeck, D., Stuhl, L., Sun, Y. L., Togano, Y., Uesaka, T., Wimmer, K., Yoneda, K., Aktas, O., Aumann, T., Chung, L. X., Flavigny, F., Franchoo, S., Gašparić, I., Gerst, R. -B., Gibelin, J., Hahn, K. I., Kim, D., Koiwai, T., Kondo, Y., Koseoglou, P., Lee, J., Lehr, C., Linh, B. D., Lokotko, T., MacCormick, M., Moschner, K., Nakamura, T., Park, S. Y., Rossi, D., Sahin, E., Sohler, D., Söderström, P. -A., Takeuchi, S., Toernqvist, H., Vaquero, V., Wagner, V., Wang, S., Werner, V., Xu, X., Yamada, H., Yan, D., Yang, Z., Yasuda, M., Zanetti, L.
Publikováno v:
Physics Letters B, 800, 135071 (2020)
Excited states in the $N=40$ isotone $^{62}$Ti were populated via the $^{63}$V$(p,2p)$$^{62}$Ti reaction at $\sim$200~MeV/u at the Radioactive Isotope Beam Factory and studied using $\gamma$-ray spectroscopy. The energies of the $2^+_1 \rightarrow 0^
Externí odkaz:
http://arxiv.org/abs/1912.07887