Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Hila Novak"'
Autor:
Elazar Besser, Anat Gelfand, Gil Moshe Lewitus, Hila Novak‐Kotzer, Shiri Procaccia, Paula Berman, Igal Louria‐Hayon, Inbar Shreiber‐Livne, Yishai Ofran, David Meiri
Publikováno v:
Cancer Communications, Vol 43, Iss 6, Pp 711-715 (2023)
Externí odkaz:
https://doaj.org/article/1a3ff57b52e44333a85c3b92ab490c20
Autor:
Iris Wyrobnik, Miryam Steinberg, Anat Gelfand, Ronen Rosenblum, Yara Eid Mutlak, Liron Sulimani, Shiri Procaccia, Yishai Ofran, Hila Novak-Kotzer, David Meiri
Publikováno v:
OncoImmunology, Vol 12, Iss 1 (2023)
ABSTRACTDuring solid tumor progression, the tumor microenvironment (TME) evolves into a highly immunosuppressive milieu. Key players in the immunosuppressive environment are regulatory myeloid cells, including myeloid-derived suppressor cells (MDSCs)
Externí odkaz:
https://doaj.org/article/39ec33dd04e2407db267ecc7cf92338a
Autor:
Daniel M. Jones, Luis A. Alvarez, Rory Nolan, Margarita Ferriz, Raquel Sainz Urruela, Xènia Massana-Muñoz, Hila Novak-Kotzer, Michael L. Dustin, Sergi Padilla-Parra
Publikováno v:
Cell Reports, Vol 18, Iss 2, Pp 443-453 (2017)
Summary: One of the key research areas surrounding HIV-1 concerns the regulation of the fusion event that occurs between the virus particle and the host cell during entry. Even if it is universally accepted that the large GTPase dynamin-2 is importan
Externí odkaz:
https://doaj.org/article/415fe24fb9b04af6902c654b76ba0c78
Autor:
Marianne Strazza, Adam Mor, Hila Novak, Michael L. Dustin, Inbar Azoulay-Alfaguter, James E. Muller, Michael Peled
The adaptor protein CrkII regulates T cell adhesion by recruiting the guanine nucleotide exchange factor C3G, an activator of Rap1. Subsequently, Rap1 stimulates the integrin LFA-1, which leads to T cell adhesion and interaction with antigen-presenti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aaed16460ee3216bd74a8265c97f0d17
https://ora.ox.ac.uk/objects/uuid:11592b3b-0978-4832-b897-144beff16eb9
https://ora.ox.ac.uk/objects/uuid:11592b3b-0978-4832-b897-144beff16eb9
Autor:
Salvatore, Valvo, Viveka, Mayya, Elena, Seraia, Jehan, Afrose, Hila, Novak-Kotzer, Daniel, Ebner, Michael L, Dustin
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1584
Supported lipid bilayers (SLB) formed on glass substrates have been a useful tool for study of immune cell signaling since the early 1980s. The mobility of lipid-anchored proteins in the system, first described for antibodies binding to synthetic pho
Autor:
Michael L. Dustin, Elena Seraia, Hila Novak-Kotzer, Daniel Ebner, Salvatore Valvo, Jehan Afrose, Viveka Mayya
Publikováno v:
The Immune Synapse ISBN: 9781493968794
Supported lipid bilayers (SLB) formed on glass substrates have been a useful tool for study of immune cell signaling since the early 1980s. The mobility of lipid-anchored proteins in the system, first described for antibodies binding to synthetic pho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e41248de14c981d4d5083ec9397588a9
http://ora.ox.ac.uk/objects/uuid:
http://ora.ox.ac.uk/objects/uuid:
Autor:
Denkberg Galit, Oryan Makler, Gideon Rechavi, Ninette Amariglio, Kfir Oved, Yoram Reiter, Hila Novak, Omer Ziv, Chen Gefen-Dor, Sinik Keren, Roy Noy, Dina Segal, Jasmine Jacob-Hirsch
Publikováno v:
The Journal of Immunology. 178:2307-2317
CTLs act as the effector arm of the cell-mediated immune system to kill undesirable cells. Two processes regulate these effector cells to prevent self reactivity: a thymic selection process that eliminates autoreactive clones and a multistage activat
Publikováno v:
The Journal of Immunology. 169:2988-2996
The MHC class I-restricted CD8 CTL effector arm of the adaptive immune response is uniquely equipped to recognize tumor cells as foreign and consequently initiates the cascade of events resulting in their destruction. However, tumors have developed s
Publikováno v:
International journal of cancer. 120(2)
Epidermal growth factor receptor (EGFR) is highly overexpressed in many tumor types. We present a new fusion molecule that can target solid tumors that express EGFR. The fusion molecule combines the advantage(s) of the well-established tumor targetin
Autor:
Roy Noy, Avital Lev, Peter Walden, Yoram Reiter, Dina Segal, Dietmar Zehn, Hila Novak, Kfir Oved
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 101(24)
A cancer immunotherapy strategy is described herein that combines the advantage of the well established tumor targeting capabilities of high-affinity recombinant fragments of Abs with the known efficient, specific, and potent killing ability of CD8 T