Zobrazeno 1 - 10
of 644
pro vyhledávání: '"Hikmat AL-Ahmadie"'
Autor:
Sakina A. Plumber, Tiffany Tate, Hikmat Al-Ahmadie, Xiao Chen, Woonyoung Choi, Merve Basar, Chao Lu, Aaron Viny, Ekatherina Batourina, Jiaqi Li, Kristjan Gretarsson, Besmira Alija, Andrei Molotkov, Gregory Wiessner, Byron Hing Lung Lee, James McKiernan, David J. McConkey, Colin Dinney, Bogdan Czerniak, Cathy Lee Mendelsohn
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Muscle invasive bladder cancers (BCs) can be divided into 2 major subgroups-basal/squamous (BASQ) tumors and luminal tumors. Since Pparg has low or undetectable expression in BASQ tumors, we tested the effects of rosiglitazone, Pparg agonist
Externí odkaz:
https://doaj.org/article/b207c60d5dd745fc8156b8526ea95f19
Autor:
Farhan Chowdry, Kelsey M. Miller, Ersan Altun, Sara E. Wobker, Gary S. Gottesman, Hikmat Al-Ahmadie, Tracy L. Rose, Eric M. Wallen, Matthew I. Milowsky
Publikováno v:
Urology Case Reports, Vol 54, Iss , Pp 102710- (2024)
We present the case of a patient with X-Linked Hypophosphatemia (XLH) and an inflammatory myofibroblastic tumor (IMT) of the bladder which prompted further investigation into the possible relationship between XLH and IMT i.e. a case of Occam's Razor
Externí odkaz:
https://doaj.org/article/34c7d4f1164a409daa648507933f99b3
Autor:
Meenakshi Anurag, Trine Strandgaard, Sung Han Kim, Yongchao Dou, Eva Comperat, Hikmat Al-Ahmadie, Brant A. Inman, Ann Taber, Iver Nordentoft, Jørgen Bjerggaard Jensen, Lars Dyrskjøt, Seth P. Lerner
Publikováno v:
iScience, Vol 27, Iss 3, Pp 109179- (2024)
Summary: Urothelial carcinoma in situ (CIS) is an aggressive phenotype of non-muscle-invasive bladder cancer. Molecular features unique to CIS compared to high-grade papillary tumors are underexplored. RNA sequencing of CIS, papillary tumors, and nor
Externí odkaz:
https://doaj.org/article/421e0ea543b3460ab11bc4bd706a726b
Autor:
Jeppe Sejerø Holm, Samuel A. Funt, Annie Borch, Kamilla Kjærgaard Munk, Anne-Mette Bjerregaard, James L. Reading, Colleen Maher, Ashley Regazzi, Phillip Wong, Hikmat Al-Ahmadie, Gopa Iyer, Tripti Tamhane, Amalie Kai Bentzen, Nana Overgaard Herschend, Susan De Wolf, Alexandra Snyder, Taha Merghoub, Jedd D. Wolchok, Morten Nielsen, Jonathan E. Rosenberg, Dean F. Bajorin, Sine Reker Hadrup
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Immune checkpoint blockade therapy is successful in a high proportion of cancer patients, but others remain unresponsive. Authors here show that therapeutic success might be predictable in metastatic bladder cancer by longitudinal analysis of the ear
Externí odkaz:
https://doaj.org/article/1e76437c13374a28980b345248e7b551
Autor:
Yasushi Kimura, Masashi Fujimori, Neeraj Raghuraman Rajagopalan, Krish Poudel, Kwanghee Kim, Karan Nagar, Laurien GPH. Vroomen, Henning Reis, Hikmat Al-Ahmadie, Jonathan A. Coleman, Govindarajan Srimathveeravalli
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Cell death and injury at the site of tumor ablation attracts macrophages. We sought to understand the status and activity of these cells while focusing on transforming growth factor-β1 (TGF-β1), a potent immunosuppressive and tumorigenic cytokine.
Externí odkaz:
https://doaj.org/article/12af866886e24025bc793c5b965e325a
Autor:
Michal Sarfaty, Karissa Whiting, Min Yuen Teo, Chung‐Han Lee, Vanessa Peters, Jennifer Durocher, Ashley M. Regazzi, Asia S. McCoy, Grace Hettich, Achim A. Jungbluth, Hikmat Al‐Ahmadie, Irina Ostrovnaya, Joshua Chaim, Dean F. Bajorin, Jonathan E. Rosenberg, Gopa Iyer, Samuel A. Funt
Publikováno v:
Cancer Medicine, Vol 10, Iss 3, Pp 1074-1083 (2021)
Abstract Background Immune checkpoint blockade has made a significant impact on the clinical outcomes of patients with metastatic urothelial carcinoma (UC). However, evidence for this approach in patients with non‐UC of the urinary tract is limited
Externí odkaz:
https://doaj.org/article/3267ae311acc413783cc2529ba317882
Autor:
Kwanghee Kim, Wenhuo Hu, François Audenet, Nima Almassi, Aphrothiti J. Hanrahan, Katie Murray, Aditya Bagrodia, Nathan Wong, Timothy N. Clinton, Shawn Dason, Vishnu Mohan, Sylvia Jebiwott, Karan Nagar, Jianjiong Gao, Alex Penson, Chris Hughes, Benjamin Gordon, Ziyu Chen, Yiyu Dong, Philip A. Watson, Ricardo Alvim, Arijh Elzein, Sizhi P. Gao, Emiliano Cocco, Alessandro D. Santin, Irina Ostrovnaya, James J. Hsieh, Irit Sagi, Eugene J. Pietzak, A. Ari Hakimi, Jonathan E. Rosenberg, Gopa Iyer, Herbert A. Vargas, Maurizio Scaltriti, Hikmat Al-Ahmadie, David B. Solit, Jonathan A. Coleman
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
The advancement of upper tract urothelial carcinoma (UTUC) research is hampered by the lack of disease-specific models. Here, the authors report patient derived xenograft and cell line models of UTUC, and show that these models retain the genomic and
Externí odkaz:
https://doaj.org/article/21deaeb5b9144f9aa0be74b0bca108b3
Autor:
Caroline T. Simon, Stephanie L. Skala, Paul D. Killen, Javed Siddiqui, Xuhong Cao, Yuanyuan Qiao, Hikmat Al-Ahmadie, Sandra I. Camelo-Piragua, Jeffrey Jentzen, Arul M. Chinnaiyan, Saravana M. Dhanasekaran, Zachery R. Reichert, Rohit Mehra
Publikováno v:
Diagnostic Pathology, Vol 14, Iss 1, Pp 1-10 (2019)
Abstract Background Rapid (“warm”) autopsies of patients with advanced metastatic cancer provide important insight into the natural history, pathobiology and histomorphology of disease in treatment-resistant tumors. Plasmacytoid urothelial carcin
Externí odkaz:
https://doaj.org/article/4578d9058286402a830e582b3e70eab9
Autor:
Wesley Yip, Daniel D. Sjoberg, Lucas M. Nogueira, Andrew T. Tracey, Ricardo G. Alvim, Peter A. Reisz, Quinlan Demac, Nicole E. Benfante, Rand W. Vanden Berg, Kwanghee Kim, Hikmat Al-Ahmadie, Oscar Lin, Bernard H. Bochner, Guido Dalbagni, S. Machele Donat, Eugene J. Pietzak, A. Ari Hakimi, David B. Solit, Avigdor Scherz, Dean F. Bajorin, Jonathan A. Coleman
Publikováno v:
Journal of Urology. 209:863-871
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::efd183efa33d80ee55155f9772db8137
https://doi.org/10.1097/ju.0000000000003202
https://doi.org/10.1097/ju.0000000000003202
Autor:
Seyram A. Doe-Tetteh, Sabrina Y. Camp, Dalicia Reales, Jett Crowdis, Anne Marie Noronha, Bernadette Wolff, Tina Alano, Jesse Galle, S. Duygu Selcuklu, Agnes Viale, Nicholas D. Socci, Ying L. Liu, William P. Tew, Carol Aghajanian, Marc Ladanyi, Meng Xiao He, Saud H. AlDubayan, Roei David Mazor, Ofer Shpilberg, Oshrat Hershkovitz-Rokah, Jose A. Riancho, Jose L. Hernandez, M. Carmen Gonzalez-Vela, Justin J. Buthorn, Manda Wilson, Amy E. Webber, Mariko Yabe, Kseniya Petrova-Drus, Marc Rosenblum, Benjamin H. Durham, Omar Abdel-Wahab, Michael F. Berger, Mark T.A. Donoghue, Andrew L. Kung, Julia Glade Bender, Neerav N. Shukla, Samuel A. Funt, Ahmet Dogan, Robert A. Soslow, Hikmat Al-Ahmadie, Darren R. Feldman, Eliezer M. Van Allen, Eli L. Diamond, David B. Solit
Publikováno v:
Clinical Cancer Research. :OF1-OF11
Purpose: To overcome barriers to genomic testing for patients with rare cancers, we initiated a program to offer free clinical tumor genomic testing worldwide to patients with select rare cancer subtypes. Experimental Design: Patients were recruited
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e0c8ef8b108c30c805d15246773a49c5
https://doi.org/10.1158/1078-0432.ccr-22-3247
https://doi.org/10.1158/1078-0432.ccr-22-3247