Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Hikaru Yamanaka"'
Publikováno v:
mBio, Vol 10, Iss 3 (2019)
ABSTRACT It has recently emerged that HIV-1 Nef counteracts the antiviral host proteins SERINC3 and SERINC5. In particular, SERINC5 inhibits the infectivity of progeny virions when incorporated. SERINC3 and SERINC5 are also counteracted by the unrela
Externí odkaz:
https://doaj.org/article/4570759b8a0d412fab429d4bc1dbaa0d
Autor:
Eric R Weiss, Elena Popova, Hikaru Yamanaka, Hyung Cheol Kim, Jon M Huibregtse, Heinrich Göttlinger
Publikováno v:
PLoS Pathogens, Vol 6, Iss 9, p e1001107 (2010)
Retroviruses engage the ESCRT pathway through late assembly (L) domains in Gag to promote virus release. HIV-1 uses a PTAP motif as its primary L domain, which interacts with the ESCRT-I component Tsg101. In contrast, certain other retroviruses prima
Externí odkaz:
https://doaj.org/article/0d0e45f261764a47ab89d8ff1e1d8041
Autor:
Eric R. Weiss, Balaji Olety, Yuanfei Wu, Heinrich G. Göttlinger, Elena Popova, Hikaru Yamanaka
Publikováno v:
mBio
mBio, Vol 10, Iss 3 (2019)
mBio, Vol 10, Iss 3, p e01071-19 (2019)
mBio, Vol 10, Iss 3 (2019)
mBio, Vol 10, Iss 3, p e01071-19 (2019)
The Nef protein of HIV-1 and the unrelated glycoGag protein of a murine leukemia virus similarly prevent the uptake of antiviral host proteins called SERINC3 and SERINC5 into HIV-1 particles, which enhances their infectiousness. We now show that alth
Publikováno v:
European Journal of Pharmacology. 745:46-51
Platelet-activating factor (PAF) is a potent lipid mediator that is implicated in numerous inflammatory diseases. C-reactive protein (CRP) is an acute-phase plasma protein that increases rapidly and dramatically in response to inflammation. In this s
Autor:
Junko Tanuma, Masafumi Takiguchi, Yoshimi Kikuchi, Hiroyuki Gatanaga, Natsuo Tachikawa, Hikaru Yamanaka, Saori Matsuoka, Katsuji Teruya, Shinichi Oka, Mamoru Fujiwara
Publikováno v:
Microbes and Infection. 10:689-698
Although a limited duration of immune activation of structured treatment interruptions (STIs) has been reported, the immune escape mechanism during STIs remains obscure. We therefore investigated the role of three immunodominant cytotoxic T lymphocyt
Publikováno v:
Chemical biologydrug design. 85(3)
Probes that can detect oxidized low-density lipoprotein (ox-LDL) in plasma and in atherosclerotic plaques can be useful for the diagnosis, prevention, and treatment of atherosclerosis. Recently, we have reported that two heptapeptides (Lys-Trp-Tyr-Ly
Publikováno v:
Chemical biologydrug design. 84(4)
The probes for specific detection of oxidized low-density lipoprotein (ox-LDL) in plasma and in atherosclerotic plaques are expected to be useful for the identification, diagnosis, prevention, and treatment for atherosclerosis. In this study, to deve
Autor:
Heinrich G. Göttlinger, Eric R. Weiss, Jon M. Huibregtse, Hikaru Yamanaka, Elena Popova, Hyung Cheol Kim
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 6, Iss 9, p e1001107 (2010)
PLoS Pathogens, Vol 6, Iss 9, p e1001107 (2010)
Retroviruses engage the ESCRT pathway through late assembly (L) domains in Gag to promote virus release. HIV-1 uses a PTAP motif as its primary L domain, which interacts with the ESCRT-I component Tsg101. In contrast, certain other retroviruses prima
Autor:
Yoshiko Usami, Ganesh Natrajan, Jean-Pierre Simorre, Heinrich G. Göttlinger, Andrew A. McCarthy, Nolwenn Miguet, Bettina Hartlieb, Patricia Renesto, Winfried Weissenhorn, Andreas Hinz, Hikaru Yamanaka
Publikováno v:
Cell Host and Microbe
Cell Host and Microbe, 2010, 7 (4), pp.314-323. ⟨10.1016/j.chom.2010.03.005⟩
Cell Host and Microbe, Elsevier, 2010, 7 (4), pp.314-323. ⟨10.1016/j.chom.2010.03.005⟩
Cell Host and Microbe, 2010, 7 (4), pp.314-323. ⟨10.1016/j.chom.2010.03.005⟩
Cell Host and Microbe, Elsevier, 2010, 7 (4), pp.314-323. ⟨10.1016/j.chom.2010.03.005⟩
SummaryThe restriction factor BST-2/tetherin contains two membrane anchors employed to retain some enveloped viruses, including HIV-1 tethered to the plasma membrane in the absence of virus-encoded antagonists. The 2.77 Å crystal structure of the BS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2653e1995574b5a58d3b978338ad05ee
https://hal.science/hal-02107142
https://hal.science/hal-02107142
Autor:
Satoshi Kimura, Shinichi Oka, Saori Matsuoka-Aizawa, Hiroyuki Gatanaga, Takao Takahashi, Hikaru Yamanaka, Pope Kosalaraksa
Publikováno v:
The Journal of infectious diseases. 195(10)
Mitochondrial toxicity is a major adverse effect of the nucleoside reverse-transcriptase inhibitors (NRTIs) used for treatment of human immunodeficiency virus type 1 (HIV-1) infection and can result in life-threatening lactic acidosis. The toxicity i