Výsledky vyhledávání - "Hikaru Okada"

Akademický článek

Outcomes and Costs in Patients with Immune Thrombotic Thrombocytopenic Purpura Receiving Front-Line Versus Delayed Caplacizumab: A US Hospital Database Study

Autor: Alix Arnaud MS, Samantha Schilsky PhD, MPH, Jackie Lucia BS, Marta Maia MS, Fernando Laredo MS, Ana Paula Marques MD, Hikaru Okada MD, PhD, Andrew W. Roberts PharmD, PhD

Publikováno v: Clinical and Applied Thrombosis/Hemostasis, Vol 30 (2024)

European real-world data indicate that front-line treatment with caplacizumab is associated with improved clinical outcomes compared with delayed caplacizumab treatment. The objective of the study was to describe the characteristics, treatment patter

Externí odkaz: https://doaj.org/article/57ed4bbdb186466689910ea32b319189

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Akademický článek

A PHASE 3 STUDY TO EVALUATE THE EFFICACY AND SAFETY OF CAPLACIZUMAB WITHOUT FIRST-LINE THERAPEUTIC PLASMA EXCHANGE IN ADULTS WITH IMMUNE-MEDIATED THROMBOTIC THROMBOCYTOPENIC PURPURA

Autor: Sriya GUNAWARDENA, MD, Angela HU, MD, Laurel A. MENAPACE, MD, Hikaru OKADA, MD, PhD, Beverly ACCOMANDO, MS, Julie LIN, MD

Publikováno v: Hematology, Transfusion and Cell Therapy, Vol 45, Iss , Pp S38-S39 (2023)

Objective: Caplacizumab (CPLZ) is indicated, in combination with therapeutic plasma exchange (TPE) and immunosuppressive therapy (IST), for the treatment of immune-mediated TTP (iTTP). TPE is a mainstay of iTTP treatment but is burdensome and associa

Externí odkaz: https://doaj.org/article/2a7999efa2b34245b549391242067d1e

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Akademický článek

A rose flavor compound activating the NRF2 pathway in dendritic cells ameliorates contact hypersensitivity in mice

Autor: Naoki Kodama, Hikaru Okada, Masakazu Hachisu, Miki Ando, Naoto Ito, Kazuki Nagata, Mayuka Katagiri, Yayoi Yasuda, Ikumi Hiroki, Takuya Yashiro, Gaku Ichihara, Masayuki Yamamoto, Chiharu Nishiyama

Publikováno v: Frontiers in Nutrition, Vol 10 (2023)

Dendritic cells (DCs), which are typical antigen-presenting cells, localize to various sites in the body, particularly the front line of infection as sentinels, and are involved in innate and adaptive immune responses. Although the functions of DCs,

Externí odkaz: https://doaj.org/article/ef4cb22f53c24cdaba6c6dc6a6180120

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