Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Hikaru G. Jolliffe"'
Autor:
Hikaru G. Jolliffe, Ebenezer Ojo, Carlota Mendez, Ian Houson, Richard Elkes, Gavin Reynolds, Angela Kong, Elizabeth Meehan, Felipe Amado Becker, Patrick M. Piccione, Sudhir Verma, Aditya Singaraju, Gavin Halbert, John Robertson
Publikováno v:
International journal of pharmaceutics. 626
Recent years have seen the advent of Quality-by-Design (QbD) as a philosophy to ensure the quality, safety, and efficiency of pharmaceutical production. The key pharmaceutical processing methodology of Direct Compression to produce tablets is also th
Publikováno v:
The Handbook of Continuous Crystallization ISBN: 9781788012140
Continuous manufacturing can offer significant operating and economic benefits to both laboratory- and production scale campaigns, compared to currently dominant, yet expensive and inefficient, batch methods. Continuous crystallisation designs offer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::86fd90aebf18d2de092cb4e8e83c9eb0
https://doi.org/10.1039/9781788013581-00542
https://doi.org/10.1039/9781788013581-00542
Publikováno v:
Jolliffe, H G & Gerogiorgis, D I 2018, ' Process modelling, design and technoeconomic evaluation for continuous paracetamol crystallisation ', Computers and Chemical Engineering, vol. 103 . https://doi.org/10.1016/j.compchemeng.2018.03.020
Systematic nonlinear optimisation is a valuable tool towards evaluating the performance of conceptual Continuous Pharmaceutical Manufacturing (CPM) flowsheets. This study considers total cost minimisation of multiple plausible design choices and eigh
Publikováno v:
Jolliffe, H G & Gerogiorgis, D I 2017, ' Technoeconomic optimisation and comparative environmental impact evaluation of continuous crystallisation and antisolvent selection for artemisinin recovery ', Computers and Chemical Engineering, vol. 103, pp. 218-232 . https://doi.org/10.1016/j.compchemeng.2017.02.046
Systematic nonlinear optimisation is a valuable tool towards evaluating the performance of conceptual Continuous Pharmaceutical Manufacturing (CPM) flowsheets. This study considers total cost minimisation of multiple plausible design choices and eigh
Publikováno v:
Jolliffe, H G & Gerogiorgis, D I 2017, ' Technoeconomic Optimization of a Conceptual Flowsheet for Continuous Separation of an Analgaesic Active Pharmaceutical Ingredient (API) ', Industrial & Engineering Chemistry Research, vol. 56, no. 15, pp. 4357-4376 . https://doi.org/10.1021/acs.iecr.6b02146
Continuous Pharmaceutical Manufacturing (CPM) has recently emerged as a promising alternative to current batch production methods, which require significant expenditures in order to ensure product quality and process reliability. Advances in new cont
Autor:
John Forsyth Russell Robertson, Alastair J. Florence, Cameron J. Brown, Gavin Halbert, Hikaru G. Jolliffe, Foteini Papathanasiou, Elke Prasad
Direct compaction tabletting, a widely used secondary downstream processing operation, has recently received significant research attention. Experimental data can be used to fit model parameters for the prediction of single-component tablet thickness
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba27b5c77547d86f63478c8570f02c20
https://strathprints.strath.ac.uk/71583/1/Jolliffe_etal_CACE_2019_Improving_the_prediction_of_multi_component_tablet_properties.pdf
https://strathprints.strath.ac.uk/71583/1/Jolliffe_etal_CACE_2019_Improving_the_prediction_of_multi_component_tablet_properties.pdf
Publikováno v:
Jolliffe, H G & Gerogiorgis, D 2016, ' Process modelling and simulation for continuous pharmaceutical manufacturing of artemisinin ', Chemical Engineering Research and Design . https://doi.org/10.1016/j.cherd.2016.02.017
Recent advances in pharmaceutical manufacturing technologies are showing the promise of continuous production: pharmaceutical firms currently rely on mature batch technology but increasingly evaluate the potential of Continuous Pharmaceutical Manufac
Publikováno v:
Jolliffe, H G & Gerogiorgis, D 2018, Process modelling, design and technoeconomic evaluation for continuous paracetamol crystallisation . in A Friedl, J Klemeš, S Radl, P Varbanov & T Wallek (eds), 28th European Symposium on Computer Aided Process Engineering . Computer-Aided Chemical Engineering, Amsterdam, pp. 1637-1642 . https://doi.org/10.1016/B978-0-444-64235-6.50285-0
Continuous Pharmaceutical Manufacturing (CPM) has received significant research interest as a way to achieve a step-change in the performance of pharmaceutical production, where innovations are incremental at best due to the current paradigm – batc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49b0f2d56b5980524f36b2e2fcd8e194
https://hdl.handle.net/20.500.11820/8e5c88b4-7025-4b2b-8e0b-3be5ced8bcb9
https://hdl.handle.net/20.500.11820/8e5c88b4-7025-4b2b-8e0b-3be5ced8bcb9
Continuous pharmaceutical manufacturing (CPM) has been recognized as a new production paradigm capable of achieving lower costs, higher yields and productivity, enhanced heat transfer and mixing, smaller equipment, and more economical energy and mate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f598070a870587085c30ecfd80a5b4e6
https://doi.org/10.1016/b978-0-444-63963-9.00004-x
https://doi.org/10.1016/b978-0-444-63963-9.00004-x
Publikováno v:
Jolliffe, H, Diab, S & Gerogiorgis, D 2017, ' Nonlinear optimisation via explicit NRTL model solubility prediction for antisolvent mixture selection in artemisinin crystallisation ', Organic Process Research and Development . https://doi.org/10.1021/acs.oprd.7b00289
Continuous Pharmaceutical Manufacturing (CPM) has the potential to revolutionise the pharmaceutical industry, with many expected benefits in terms of cost, efficiency and quality. Process modeling and optimization are valuable methodologies for compa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3dd45488a2f258b29dd801669b2a1a63
https://hdl.handle.net/20.500.11820/700b4e91-9ac0-436a-a1aa-c3e0dcd3ab6f
https://hdl.handle.net/20.500.11820/700b4e91-9ac0-436a-a1aa-c3e0dcd3ab6f