Non-parenchymal TREM-2 protects the liver from immune-mediated hepatocellular damage

Autor: Perugorria, M.J. (María J.), Esparza-Baquer, A. (Aitor), Oakley, F. (Fiona), Labiano, I. (Ibone), Korosec, A. (Ana), Jais, A. (Alexander), Mann, J. (Jelena), Tiniakos, D. (Dina), Santos-Laso, A. (Alvaro), Arbelaiz, A. (Ander), Gawish, R. (Riem), Sampedro, A. (Ana), Fontanellas, A. (Antonio), Hijona, E. (Elizabeth), Jimenez-Agüero, R. (Raul), Esterbauer, H. (Harald), Stoiber, D. (Dagmar), Bujanda, L. (Luis), Banales, J.M. (Jesús M.), Knapp, S. (Sylvia), Sharif, O. (Omar), Mann, D.A. (Derek A.)

Publikováno v: Gut
Dadun. Depósito Académico Digital de la Universidad de Navarra
Consejo Superior de Investigaciones Científicas (CSIC)

Objective: Liver injury impacts hepatic inflammation in part via Toll-like receptor (TLR) signalling. Triggering receptor expressed on myeloid cells 2 (TREM-2) modulates TLR4-mediated inflammation in bone marrow (BM)-derived macrophages but its funct

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::75314552af0fb17e99df0d54b26ace65
http://europepmc.org/articles/PMC6580759