Zobrazeno 1 - 10
of 6 853
pro vyhledávání: '"High grade glioma"'
Autor:
Arnault Tauziède-Espariat, Lea L. Friker, Gunther Nussbaumer, Brigitte Bison, Volodia Dangouloff-Ros, Alice Métais, David Sumerauer, Josef Zamecnik, Martin Benesch, Thomas Perwein, Dannis van Vuurden, Pieter Wesseling, Andrés Morales La Madrid, Maria Luisa Garrè, Manila Antonelli, Felice Giangaspero, Torsten Pietsch, Dominik Sturm, David T. W. Jones, Stefan M. Pfister, Yura Grabovska, Alan Mackay, Chris Jones, Jacques Grill, Yassine Ajlil, André O. von Bueren, Michael Karremann, Marion Hoffmann, Christof M. Kramm, Robert Kwiecien, David Castel, Gerrit H. Gielen, Pascale Varlet
Publikováno v:
Acta Neuropathologica Communications, Vol 12, Iss 1, Pp 1-11 (2024)
Abstract Diffuse pediatric-type high-grade gliomas (pedHGG), H3- and IDH-wildtype, encompass three main DNA-methylation-based subtypes: pedHGG-MYCN, pedHGG-RTK1A/B/C, and pedHGG-RTK2A/B. Since their first description in 2017 tumors of pedHGG-RTK2A/B
Externí odkaz:
https://doaj.org/article/a314c4fae9f64dd98df77f621bcc505c
Publikováno v:
Cancer Management and Research, Vol Volume 16, Pp 1617-1626 (2024)
Xuexue Bai,1 Hao Xing,1 Ming Feng,1 Wenbin Ma,1 Shiyong Wang2 1Department of Neurosurgery, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, People’s Republic of China; 2Department
Externí odkaz:
https://doaj.org/article/7d39029f8cc74a36b6d37d52c6121fd4
Autor:
Tomohiro Hosoya, Atsushi Kambe, Irfan Kesumayadi, Karen Makishima, Shuntaro Sueyoshi, Makoto Sakamoto, Masamichi Kurosaki
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract In this study, we focused on calcification and diffusion restriction, which sometimes appear around the resection cavity or periventricular white matter in patients with high-grade glioma (HGG) treated with bevacizumab (BVZ), as candidate im
Externí odkaz:
https://doaj.org/article/aa13a6b63e2b4760a2c9b046e2466350
Autor:
Michael Chang, Mohamed Sherief, Maria Ioannou, Viveka Chinnasamy, Lucy Chen, Michael Frost, Michelle Mattson-Hoss, Herb Sarnoff, David O. Kamson, Matthias Holdhoff, Debraj Mukherjee, Chetan Bettegowda, Jordina Rincon-Torroella, Victoria Croog, Peng Huang, Fausto J. Rodriguez, Calixto-Hope G. Lucas, Karisa C. Schreck
Publikováno v:
Acta Neuropathologica Communications, Vol 12, Iss 1, Pp 1-10 (2024)
Abstract Background NF1 inactivation is associated with sensitivity to MEK inhibitor targeted therapy in low-grade and some high-grade gliomas. NF1 loss may also be a harbinger of exploitable vulnerabilities in IDH-wildtype glioblastoma (GBM). Accura
Externí odkaz:
https://doaj.org/article/750d716ba61347bc87ffa9e517a87e9c
Autor:
Olga Kim, Zach Sergi, Guangyang Yu, Kazutoshi Yamamoto, Martha Quezado, Zied Abdullaev, Danel R. Crooks, Shun Kishimoto, Qi Li, Peng Lu, Burchelle Blackman, Thorkell Andresson, Xiaolin Wu, Bao Tran, Jun S. Wei, Wei Zhang, Meili Zhang, Hua Song, Javed Khan, Murali C. Krishna, Jeffrey R. Brender, Jing Wu
Publikováno v:
Acta Neuropathologica Communications, Vol 12, Iss 1, Pp 1-18 (2024)
Abstract Malignant transformation (MT) is commonly seen in IDH-mutant gliomas. There has been a growing research interest in revealing its underlying mechanisms and intervening prior to MT at the early stages of the transforming process. Here we esta
Externí odkaz:
https://doaj.org/article/4b329e13fa87456ea2628bbe4d0bfe40
Autor:
Sreejith Vidyadharan, B. V. V. S. N. Prabhakar Rao, P. Yogeeswari, C. Kesavadas, Venkateswaran Rajagopalan
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Glioma, a predominant type of brain tumor, can be fatal. This necessitates an early diagnosis and effective treatment strategies. Current diagnosis is based on biopsy, prompting the need for non invasive neuroimaging alternatives. Diffusion
Externí odkaz:
https://doaj.org/article/083c82908a3846aea12fbe8b77d91805
Publikováno v:
Asian Journal of Medical Sciences, Vol 15, Iss 8, Pp 41-47 (2024)
Background: Central nervous system tumors are the 10th most prevalent cause of mortality worldwide. The 2016 World Health Organization (WHO) classification of high grade gliomas (HGG) has identified Isocitrate dehydrogenase 1 (IDH 1) mutation as one
Externí odkaz:
https://doaj.org/article/12cb8f084624494d8aff9b8078103077
Autor:
Andrew L. DeGroot, MD, Emily Morris, MD, Omar Hussain, MD, David Smullen, MD, Vladimir Ivanovic, MD, Max Krucoff, MD
Publikováno v:
Radiology Case Reports, Vol 19, Iss 8, Pp 3376-3381 (2024)
Intraoperative magnetic resonance imaging (iMRI) is a powerful tool used to verify maximal safe resection of gliomas. However, unsuspected new or incidental findings can present difficult clinical scenarios. Here we present a case of a large supraten
Externí odkaz:
https://doaj.org/article/d2505cc81288468b9c2997ada5d53a99
Autor:
Craig Erker, Magimairajan Issai Vanan, Valérie Larouche, Liana Nobre, Chantel Cacciotti, Stéphanie Vairy, Shayna Zelcer, Adam Fleming, Eric Bouffet, Nada Jabado, Geneviève Legault, Samuele Renzi, Tara McKeown, Bruce Crooks, Nirav Thacker, Vijay Ramaswamy, Hallie Coltin, Lucie Lafay-Cousin, Sylvia Cheng, Juliette Hukin, Seth Andrew Climans, Mary Jane Lim-Fat, Sarah McKillop, Sarah Lapointe, Mélanie Alves, Julie Bennett, Uri Tabori, Sébastien Perreault
Publikováno v:
Current Oncology, Vol 31, Iss 7, Pp 4022-4029 (2024)
Background: The treatment of BRAF V600E gliomas with BRAF inhibitors (BRAFis) and MEK inhibitors (MEKis) has been increasingly integrated into clinical practice for pediatric low-grade gliomas (PLGGs) and pediatric high-grade gliomas (HGGs). However,
Externí odkaz:
https://doaj.org/article/18a6d0e5930647838048e65c909b0585
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-13 (2024)
Abstract Background The clinical features of cerebellar high-grade gliomas (cHGGs) in adults have not been thoroughly explored. This large-scale, population-based study aimed to comprehensively outline these traits and construct a predictive model. M
Externí odkaz:
https://doaj.org/article/59b0b85e75d14e6eb3a8c681623404bd