Zobrazeno 1 - 10
of 6 853
pro vyhledávání: '"High content"'
Publikováno v:
Biosafety and Health, Vol 6, Iss 5, Pp 270-278 (2024)
Despite the availability of vaccines and antiviral treatments, the continued emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants and breakthrough infections underscores the need for new, potent antiviral therapies. In a
Externí odkaz:
https://doaj.org/article/53fec2a4cdae434b91969732ce7154e6
Publikováno v:
Veterinary Research, Vol 55, Iss 1, Pp 1-17 (2024)
Abstract Feline infectious peritonitis (FIP) is a lethal, immune-mediated disease in cats caused by feline infectious peritonitis virus (FIPV), a biotype of feline coronavirus (FCoV). In contrast to feline enteric coronavirus (FECV), which exclusivel
Externí odkaz:
https://doaj.org/article/6f3e998051954a829bc96568af26df53
Autor:
Jiahui Li, Xiaorong Fan, Yinghui Geng, Limei Zhang, Xiaorong Huang, Hengyue Xie, Tao Xu, Meng Li, Longchao Zhuo, Zhenting Liu, Zengyun Jian
Publikováno v:
Journal of Materials Research and Technology, Vol 32, Iss , Pp 470-477 (2024)
In present work, non-isothermal crystallization behavior for novel Cr50Fe6Co7Mo14C15B6Y2 metallic glass (MG) with super high content of Cr and excellent merits was investigated by differential scanning calorimeter and X-ray diffraction. Both of the K
Externí odkaz:
https://doaj.org/article/a20ad5547a3b446d9aa54a6126a6ac71
Autor:
Suleyman B. Bozal, Greg Sjogren, Antonio P. Costa, Joseph S. Brown, Shannon Roberts, Dylan Baker, Paul Gabriel, Jr., Benjamin T. Ristau, Michael Samuels, William F. Flynn, Paul Robson, Elise T. Courtois
Publikováno v:
SLAS Discovery, Vol 29, Iss 7, Pp 100182- (2024)
The use of organoid models in biomedical research has grown substantially since their inception. As they gain popularity among scientists seeking more complex and biologically relevant systems, there is a direct need to expand and clarify potential u
Externí odkaz:
https://doaj.org/article/eb7fa212871d4f388d6efcd695a127e0
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 23, Iss , Pp 2949-2962 (2024)
Quantitative morphological phenotyping (QMP) is an image-based method used to capture morphological features at both the cellular and population level. Its interdisciplinary nature, spanning from data collection to result analysis and interpretation,
Externí odkaz:
https://doaj.org/article/a973de94a30c4195bc13924a47b6dad4
Autor:
Adriana Borowa, Dawid Rymarczyk, Marek Żyła, Maciej Kańdula, Ana Sánchez-Fernández, Krzysztof Rataj, Łukasz Struski, Jacek Tabor, Bartosz Zieliński
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 23, Iss , Pp 1181-1188 (2024)
Biomedical imaging techniques such as high content screening (HCS) are valuable for drug discovery, but high costs limit their use to pharmaceutical companies. To address this issue, The JUMP-CP consortium released a massive open image dataset of che
Externí odkaz:
https://doaj.org/article/bd33caae48344f6580a7b4d8b6cca8c9
Publikováno v:
Zhongguo shipin weisheng zazhi, Vol 36, Iss 6, Pp 751-757 (2024)
High content analysis combines automated microscopy and quantitative image analysis to visualize in vitro models for multi-parameter analysis， which has the advantages of high efficiency， rapidity and multi-targeting， and it has been applied in
Externí odkaz:
https://doaj.org/article/4518ceab8c31435a873a94f69986fa00
Autor:
Rodrigo Lata, Liesbeth Steegmans, Ranie Kellens, Marnik Nijs, Hugo Klaassen, Matthias Versele, Frauke Christ, Zeger Debyser
Publikováno v:
Translational Medicine Communications, Vol 9, Iss 1, Pp 1-14 (2024)
Abstract Rett syndrome (OMIM 312750) is a rare neurodevelopmental disorder caused by de novo mutations in the Methyl-CpG Binding Protein 2 (MeCP2) gene located on the X-chromosome, typically affecting girls. Rett syndrome symptoms, characterized by m
Externí odkaz:
https://doaj.org/article/21119448f0024949a72193f1521e4bd7
Autor:
Haneen S. Alsehli, Errin Roy, Thomas Williams, Alicja Kuziola, Yunzhe Guo, Cecile A. Dreiss, Jeremy B.A. Green, Eileen Gentleman, Davide Danovi
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 12 (2024)
IntroductionCell lineage specification is tightly associated with profound morphological changes in the developing human embryo, particularly during gastrulation. The interplay between mechanical forces and biochemical signals is poorly understood.Me
Externí odkaz:
https://doaj.org/article/b25bac5cac2a45629d828abf4aa2484d
Publikováno v:
Neurobiology of Disease, Vol 201, Iss , Pp 106667- (2024)
Huntington's Disease (HD) is an inheritable neurodegenerative condition caused by an expanded CAG trinucleotide repeat in the HTT gene with a direct correlation between CAG repeats expansion and disease severity with earlier onset-of- disease. Previo
Externí odkaz:
https://doaj.org/article/dfb094b42c054460a5dfa8c2dd253ef3