Recombinant Human CD19 in CHO-K1 Cells: Glycosylation Patterns as a Quality Attribute of High Yield Processes

Autor: Magdalena Billerhart, Monika Hunjadi, Vanessa Hawlin, Clemens Grünwald-Gruber, Daniel Maresch, Patrick Mayrhofer, Renate Kunert

Publikováno v: International Journal of Molecular Sciences, Vol 24, Iss 13, p 10891 (2023)

CD19 is an essential protein in personalized CD19-targeting chimeric antigen receptor (CAR)-T cell-based cancer immunotherapies and CAR-T cell functionality evaluation. However, the recombinant expression of this “difficult to-express” (DTE) prot

Externí odkaz: https://doaj.org/article/bb8f7a0b33524000a62b348d822527ae

Improving E. coli growth performance by manipulating small RNA expression

Autor: Alejandro Negrete, Joseph Shiloach

Publikováno v: Microbial Cell Factories, Vol 16, Iss 1, Pp 1-12 (2017)

Abstract Efficient growth of E. coli, especially for production of recombinant proteins, has been a challenge for the biotechnological industry since the early 1970s. By employing multiple approaches, such as different media composition, various grow

Externí odkaz: https://doaj.org/article/aeeb76f6596f4ff6a5137f62b2d041fc

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Zymobacter palmae pyruvate decarboxylase production process development : Cloning in Escherichia coli, fed-batch culture and purification

Autor: Natàlia Alcover, Marina Guillén, Albert Carceller, Gregorio Álvaro

Publikováno v: Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Recercat: Dipósit de la Recerca de Catalunya
Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Eng Life Sci
Recercat. Dipósit de la Recerca de Catalunya
instname

Pyruvate decarboxylase (PDC) is responsible for the decarboxylation of pyruvate, producing acetaldehyde and carbon dioxide and is of high interest for industrial applications. PDC is a very powerful tool in the enzymatic synthesis of chiral amines by

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf69752cd6f9f26202daece7c84f5960
https://ddd.uab.cat/record/217010

Enhanced bioproduction of poly-3-hydroxybutyrate from wheat straw lignocellulosic hydrolysates

Autor: Frederik van Keulen, M. Teresa Cesário, M. Manuela R. da Fonseca, Bruno Sommer Ferreira, Rodrigo S. Raposo, M. Catarina M.D. de Almeida

Publikováno v: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Agência para a Sociedade do Conhecimento (UMIC)-FCT-Sociedade da Informação
instacron:RCAAP
New Biotechnology

Project: EC/FP7/246449 - New tailor-made PNB-based nanocomposites for high performance applications produced from environmentally friendly production routes NOTICE: this is the author’s version of a work that was accepted for publication in New Bio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2bec2ce799d422a872b0aa112c1db5c
https://hdl.handle.net/10400.26/6276