Zika virus impairs the development of blood vessels in a mouse model of congenital infection

Autor: Garcez, P. P., Stolp, H. B., Sravanam, S., Christoff, R. R., Ferreira, J. C. C. G., Dias, A. A., Pezzuto, P., Higa, L. M., Barbeito-Andrés, J., Ferreira, R. O., Andrade, C. B V., Siqueira, M., Santos, T. M. P., Drumond, J., Hoerder-Suabedissen, A., de Lima, C. V. F., Tovar-Moll, F., Lopes, R. T., Fragel-Madeira, L., Lent, R., Ortiga-Carvalho, T. M., Stipursky, J., Bellio, M., Tanuri, A., Molnár, Z.

Publikováno v: CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
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Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)
Scientific Reports
Scientific Reports (Nature)

Zika virus (ZIKV) is associated with brain development abnormalities such as primary microcephaly, a severe reduction in brain growth. Here we demonstrated in vivo the impact of congenital ZIKV infection in blood vessel development, a crucial step in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::f3b6cecb76e2dabcebd503bd607cace0
http://www.nature.com/articles/s41598-018-31149-3

Zika virus impairs the development of blood vessels in a mouse model of congenital infection.

Autor: Garcez PP; Institute of Biomedical Sciences, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil. ppgarcez@gmail.com.; Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK. ppgarcez@gmail.com., Stolp HB; Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK. hstolp@rvc.ac.uk.; Centre for the Developing Brain, Department of Perinatal Imaging & Health, King's College London, London, UK. hstolp@rvc.ac.uk., Sravanam S; Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK., Christoff RR; Institute of Biomedical Sciences, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil., Ferreira JCCG; Institute of Biomedical Sciences, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil., Dias AA; Microbiology Institute Paulo de Góes, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil., Pezzuto P; Institute of Biology, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil., Higa LM; Institute of Biology, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil., Barbeito-Andrés J; Institute of Biomedical Sciences, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil., Ferreira RO; Institute of Biomedical Sciences, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil., Andrade CBV; Institute of Biophysics Carlos Chagas Filho, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil., Siqueira M; Institute of Biomedical Sciences, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil., Santos TMP; Nuclear Instrumentation Laboratory, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil., Drumond J; Institute of Biomedical Sciences, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil., Hoerder-Suabedissen A; Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK., de Lima CVF; D'Or Institute for Research and Education (IDOR), Rio de Janeiro, Brazil., Tovar-Moll F; Institute of Biomedical Sciences, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.; D'Or Institute for Research and Education (IDOR), Rio de Janeiro, Brazil., Lopes RT; Nuclear Instrumentation Laboratory, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil., Fragel-Madeira L; Department of Neurobiology, Institute of Biology, Fluminense Federal University, Niterói, Brazil., Lent R; Institute of Biomedical Sciences, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil., Ortiga-Carvalho TM; Institute of Biophysics Carlos Chagas Filho, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil., Stipursky J; Institute of Biomedical Sciences, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil., Bellio M; Microbiology Institute Paulo de Góes, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil., Tanuri A; Institute of Biology, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil., Molnár Z; Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK. zoltan.molnar@dpag.ox.ac.uk.

Publikováno v: Scientific reports [Sci Rep] 2018 Aug 24; Vol. 8 (1), pp. 12774. Date of Electronic Publication: 2018 Aug 24.