Zobrazeno 1 - 10
of 109
pro vyhledávání: '"Hifzur R. Siddique"'
Autor:
Deepti Singh, Mohammad Afsar Khan, Dhruv Mishra, Aditya Goel, Mairaj Ahmed Ansari, Kafil Akhtar, Hifzur R. Siddique
Publikováno v:
Translational Oncology, Vol 43, Iss , Pp 101920- (2024)
Background: The “one drug-one target” paradigm has various limitations affecting drug efficacy, such as resistance profiles and adverse effects. Combinational therapies help reduce unexpected off-target effects and accelerate therapeutic efficacy
Externí odkaz:
https://doaj.org/article/439cf31a97c849f0a5e65667377343af
Autor:
Da-Wei Yeh, Xuyao Zhao, Hifzur R. Siddique, Mengmei Zheng, Hye Yeon Choi, Tatsuya Machida, Padmini Narayanan, Yi Kou, Vasu Punj, Stanley M. Tahara, Douglas E. Feldman, Lin Chen, Keigo Machida
Publikováno v:
Cell Death Discovery, Vol 9, Iss 1, Pp 1-15 (2023)
Abstract RNA-binding protein Musashi 2 (MSI2) is elevated in several cancers and is linked to poor prognosis. Here, we tested if MSI2 promotes MYC and viral mRNA translation to induce self-renewal via an internal ribosome entry sequence (IRES). We pe
Externí odkaz:
https://doaj.org/article/f53b059996d14f06981134f03c1b966e
Publikováno v:
Chemistry, Vol 5, Iss 1, Pp 201-222 (2023)
Redox homeostasis, a dynamic process ensuring a balance between cellular oxidizing and reducing reactions, is crucial for maintaining healthy cellular physiology and regulating many biological processes, requiring continuous monitoring and fine-tunin
Externí odkaz:
https://doaj.org/article/ce69c89ed16e4acb947844fc055b5c8c
Autor:
Hifzur R. Siddique
Publikováno v:
Frontiers in Genetics, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/51c6ab5be853463f97e216d27da08a7b
Autor:
Meenakshi Gupta, Deepti Singh, Shruti Rastogi, Hifzur R. Siddique, Noura Al-Dayan, Ajaz Ahmad, Mohammad Sikander, Maryam Sarwat
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Background: Guggulsterone (pregna-4,17-diene-3,16-dione; C21H28O2) is an effective phytosterol isolated from the gum resin of the tree Commiphora wightii (Family Burseraceae) and is responsible for many of the properties of guggul. This plant is wide
Externí odkaz:
https://doaj.org/article/9a8bd685738449daa13bb00d1ae32be9
Publikováno v:
Life, Vol 13, Iss 10, p 1976 (2023)
Prostate cancer (CaP) is one of the most prevalent male malignancies, accounting for a considerable number of annual mortalities. However, the prompt identification of early-stage CaP often faces delays due to diverse factors, including socioeconomic
Externí odkaz:
https://doaj.org/article/b185a4039bf34ab4828d0ee97f2faacf
Autor:
Hye Yeon Choi, Hifzur R. Siddique, Mengmei Zheng, Yi Kou, Da-Wei Yeh, Tatsuya Machida, Chia-Lin Chen, Dinesh Babu Uthaya Kumar, Vasu Punj, Peleg Winer, Alejandro Pita, Linda Sher, Stanley M. Tahara, Ratna B. Ray, Chengyu Liang, Lin Chen, Hidekazu Tsukamoto, Keigo Machida
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Normal stem cells are maintained by asymmetric cell division, but this process is dysregulated in tumour initiating stem-like cells (TICs). Here, the authors show that TBC1D15 impairs the asymmetric division machinery and activates NOTCH pathway for
Externí odkaz:
https://doaj.org/article/b860fba9de8448de8c15f0811ec7cae9
Publikováno v:
ACS Omega, Vol 5, Iss 25, Pp 15218-15228 (2020)
Externí odkaz:
https://doaj.org/article/47edbd35f9014f028052aa81e81c12ed
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2022)
Circular RNAs (circRNAs) are the newly uncovered class of non-coding RNAs being cognized as profound regulators of gene expression in developmental and disease biology. These are the covalently closed RNAs synthesized when the pre-mRNA transcripts un
Externí odkaz:
https://doaj.org/article/8fc0b71b5bb64dba8f8bff9ebe01cf05
Autor:
Deepti Singh, Mohammad Afsar Khan, Kafil Akhtar, Sumbul Rehman, Sabiha Parveen, K. M. Yusuf Amin, Hifzur R. Siddique
Publikováno v:
Drug and Chemical Toxicology. :1-13
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cea464f8650641bd256695d55979b747
https://doi.org/10.1080/01480545.2022.2124519
https://doi.org/10.1080/01480545.2022.2124519