Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Hieu T. Van"'
Autor:
Mauricio S. Caetano, Maya Hassane, Hieu T. Van, Emmanuel Bugarin, Amber M. Cumpian, Christina L. McDowell, Carolina Gonzalez Cavazos, Huiyuan Zhang, Shanshan Deng, Lixia Diao, Jing Wang, Scott E. Evans, Carmen Behrens, Ignacio I. Wistuba, Susan A. W. Fuqua, Huang Lin, Laura P. Stabile, Stephanie S. Watowich, Humam Kadara, Seyed Javad Moghaddam
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Proinflammatory and immunomodulatory events that drive development of K-ras mutant lung adenocarcinoma (LUAD) are poorly understood. Here they develop a lung epithelial specific K-ras mutant/Stat3 conditional knockout mouse model and show a sex-speci
Externí odkaz:
https://doaj.org/article/a75e60d748374ccbaa270592719a5d9b
Autor:
Kylee J. Veazey, Hieu T. Van, Donghang Cheng, Han Xu, Mabel Perez-Oquendo, Mark T. Bedford, Michael R. Green, Oscar D. Villarreal, Sabrina A. Stratton, Guozhen Gao, Yue Lu, Kevin Lin, Margarida A. Santos
Publikováno v:
Leukemia
Somatic mutations affecting CREBBP and EP300 are a hallmark of diffuse large B-cell lymphoma (DLBCL). These mutations are frequently monoallelic, within the histone acetyltransferase (HAT) domain and usually mutually exclusive, suggesting that they m
Autor:
Hieu T. Van, Margarida A. Santos
Publikováno v:
Epigenetics and DNA Damage ISBN: 9780323910811
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5df8f7aee6261e505d4970ef6e5f790f
https://doi.org/10.1016/b978-0-323-91081-1.00007-8
https://doi.org/10.1016/b978-0-323-91081-1.00007-8
Autor:
Débora Kristina Alves-Fernandes, Ana Luisa Pedroso Ayub, Nilofer S. Azad, Khalil Azizian, Marina Baretti, Nikola Bowden, Kate H. Brettingham-Moore, Jessica Buck, Dayna Challis, Jonathan Dow, Raelene Endersby, Shinjini Ganguly, Anthony Ghanem, Sebastiano Giallongo, Peter M. Glazer, Nassim Gorjizadeh, Negar Gorjizadeh, Miriam Galvonas Jasiulionis, Philippe Johann To Berens, Ansar Karimian, Marcela Teatin Latancia, Giovana da Silva Leandro, Oriana Lo Re, Carlos Frederico Martins Menck, Omar Y. Mian, Tomoko Miyake, Jean Molinier, Apiwat Mutirangura, Bruna de Oliveira Perestrelo, Guilherme Cavalcante Pessoa, Nathalia Quintero-Ruiz, Salimata Ousmane Sall, Margarida A. Santos, Mikio Shimada, Moein Shirzad, Hieu T. Van, Manlio Vinciguerra
Publikováno v:
Epigenetics and DNA Damage ISBN: 9780323910811
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::63576a9b74f454ca4395da276e6b8f93
https://doi.org/10.1016/b978-0-323-91081-1.09991-x
https://doi.org/10.1016/b978-0-323-91081-1.09991-x
Methyl-lysine readers PHF20 and PHF20L1 define two distinct gene expression-regulating NSL complexes
Autor:
Hieu T. Van, Peter R. Harkins, Avni Patel, Abhinav K. Jain, Yue Lu, Mark T. Bedford, Margarida A. Santos
Publikováno v:
The Journal of biological chemistry. 298(3)
The methyl-lysine readers plant homeodomain finger protein 20 (PHF20) and its homolog PHF20-like protein 1 (PHF20L1) are known components of the nonspecific lethal (NSL) complex that regulates gene expression through its histone acetyltransferase act
Autor:
Margarida A. Santos, Hieu T. Van
Publikováno v:
Cell Cycle. 17:2399-2410
The timely and precise repair of DNA damage, or more specifically DNA double-strand breaks (DSBs) – the most deleterious DNA lesions, is crucial for maintaining genome integrity and cellular homeostasis. An appropriate cellular response to DNA DSBs
Autor:
Shanshan Deng, Huang Lin, Jing Wang, Ignacio I. Wistuba, Carmen Behrens, Mauricio S. Caetano, Emmanuel Bugarin, Scott E. Evans, Lixia Diao, Amber M. Cumpian, Stephanie S. Watowich, Seyed Javad Moghaddam, Hieu T. Van, Maya Hassane, Humam Kadara, Huiyuan Zhang, Laura P. Stabile, Susan A. W. Fuqua, Carolina Gonzalez Cavazos, Christina McDowell
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Nature Communications
Nature Communications
Lung adenocarcinomas (LUADs) with mutations in the K-ras oncogene display dismal prognosis. Proinflammatory and immunomodulatory events that drive development of K-ras mutant LUAD are poorly understood. Here, we develop a lung epithelial specific K-r
Autor:
Junichi Kikuta, Masaru Ishii, Yue Lu, Kai Ge, Hieu T. Van, Kylee J. Veazey, Margarida A. Santos, Kevin Lin, Prosun Das, Saakshi Kaushik, André Nussenzweig
The bone is essential for locomotion, calcium storage, and harboring the hematopoietic stem cells (HSCs) that supply the body with mature blood cells throughout life. HSCs reside at the interface of the bone and bone marrow (BM), where active bone re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fff678d2aa90d71d2ec6f03d063c68d
https://europepmc.org/articles/PMC6205459/
https://europepmc.org/articles/PMC6205459/
Abstract 3974: Gender specific function of epithelial IL-6-STAT3 pathway in K-ras mutant lung cancer
Autor:
Christina McDowell, Stephanie S. Watowich, Humam Kadara, Huiyuan Zhang, Scott E. Evans, Emmanuel Bugarin, Amber M. Cumpian, Seyed Javad Moghaddam, Hieu T. Van, Mauricio S. Caetano
Publikováno v:
Cancer Research. 77:3974-3974
Activating mutations of K-ras are the most common oncogenic alterations found in lung cancer, and are heavily associated with tobacco exposure and poor prognosis. Using a conditional lung cancer mouse model (CC-LR), we showed that K-ras mutant lung t