Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Hieu S Vu"'
Autor:
Bryn D Webb, Sara M Nowinski, Ashley Solmonson, Jaya Ganesh, Richard J Rodenburg, Joao Leandro, Anthony Evans, Hieu S Vu, Thomas P Naidich, Bruce D Gelb, Ralph J DeBerardinis, Jared Rutter, Sander M Houten
Publikováno v:
eLife, Vol 12 (2023)
Malonyl-CoA-acyl carrier protein transacylase (MCAT) is an enzyme involved in mitochondrial fatty acid synthesis (mtFAS) and catalyzes the transfer of the malonyl moiety of malonyl-CoA to the mitochondrial acyl carrier protein (ACP). Previously, we s
Externí odkaz:
https://doaj.org/article/e492c4b03a0a40868acd1fea5b29bfde
Autor:
Mona Hoseini Soflaee, Rushendhiran Kesavan, Umakant Sahu, Alpaslan Tasdogan, Elodie Villa, Zied Djabari, Feng Cai, Diem H. Tran, Hieu S. Vu, Eunus S. Ali, Halie Rion, Brendan P. O’Hara, Sherwin Kelekar, James Hughes Hallett, Misty Martin, Thomas P. Mathews, Peng Gao, John M. Asara, Brendan D. Manning, Issam Ben-Sahra, Gerta Hoxhaj
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Nucleotides are essential for different biological processes and have been also associated to cancer development. Depleting cellular nucleotides is a strategy commonly employed to target cancers. Here, the authors show that purine depletion induces s
Externí odkaz:
https://doaj.org/article/e65828f4fe7b450899c62fcdaa40754f
Autor:
Nanxiang Xiong, Xiaofei Gao, Hongyang Zhao, Feng Cai, Fang-cheng Zhang, Ye Yuan, Weichao Liu, Fangping He, Lauren G. Zacharias, Hong Lin, Hieu S. Vu, Chao Xing, Dong-Xiao Yao, Fei Chen, Benyan Luo, Wenzhi Sun, Ralph J. DeBerardinis, Hao Xu, Woo-ping Ge
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
Cellular metabolism is altered in many cancer types and the advent of metabolomics has allowed us to understand more about how this is dysregulated. Here, the authors report a method named CARVE to analyse the arterial supply and venous drainage of g
Externí odkaz:
https://doaj.org/article/fee93f55ed074390b6efbed9fe4da21d
Autor:
Sibtain Ahmed, Ayra Siddiqui, Ralph J. DeBerardinis, Min Ni, Wen Gu Lai, Feng Cai, Hieu S. Vu, Bushra Afroze
Publikováno v:
Annals of Medicine & Surgery. 85:712-717
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::82065dc78deb36ce501feb930848ceeb
https://doi.org/10.1097/ms9.0000000000000326
https://doi.org/10.1097/ms9.0000000000000326
Autor:
Min Ni, Ashley Solmonson, Chunxiao Pan, Chendong Yang, Dan Li, Ashley Notzon, Ling Cai, Gerardo Guevara, Lauren G. Zacharias, Brandon Faubert, Hieu S. Vu, Lei Jiang, Bookyung Ko, Noriko Merida Morales, Jimin Pei, Gonçalo Vale, Dinesh Rakheja, Nick V. Grishin, Jeffrey G. McDonald, Garrett K. Gotway, Markey C. McNutt, Juan M. Pascual, Ralph J. DeBerardinis
Publikováno v:
Cell Reports, Vol 27, Iss 5, Pp 1376-1386.e6 (2019)
Summary: Inborn errors of metabolism (IEMs) link metabolic defects to human phenotypes. Modern genomics has accelerated IEM discovery, but assessing the impact of genomic variants is still challenging. Here, we integrate genomics and metabolomics to
Externí odkaz:
https://doaj.org/article/20192b4961c6412d9347da31fb8bfd47
Autor:
Pravat Kumar Parida, Mauricio Marquez-Palencia, Suvranil Ghosh, Nitin Khandelwal, Kangsan Kim, Vidhya Nair, Xiao-Zheng Liu, Hieu S. Vu, Lauren G. Zacharias, Paula I. Gonzalez-Ericsson, Melinda E. Sanders, Bret C. Mobley, Jeffrey G. McDonald, Andrew Lemoff, Yan Peng, Cheryl Lewis, Gonçalo Vale, Nils Halberg, Carlos L. Arteaga, Ariella B. Hanker, Ralph J. DeBerardinis, Srinivas Malladi
Publikováno v:
Nature Cancer.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bfa0c6bfc7bfca8393c90b2fca646f2b
https://doi.org/10.1038/s43018-023-00563-6
https://doi.org/10.1038/s43018-023-00563-6
Autor:
Zheng Wu, Divya Bezwada, Robert C Harris, Chunxiao Pan, Phong T Nguyen, Brandon Faubert, Ling Cai, Feng Cai, Hieu S. Vu, Hongli Chen, Misty Martin- Sandoval, Duyen Do, Wen Gu, Yuannyu Zhang, Bookyung Ko, Bailey Brooks, Sherwin Kelekar, Yuanyuan Zhang, Lauren G Zacharias, K. Celeste Oaxaca, Thomas P Mathews, Javier Garcia-Bermudez, Min Ni, Ralph J. DeBerardinis
Publikováno v:
bioRxiv
SUMMARYCancer cells reprogram their metabolism to support cell growth and proliferation in harsh environments. While many studies have documented the importance of mitochondrial oxidative phosphorylation (OXPHOS) in tumor growth, some cancer cells ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc11f975d120e82f91241623f27adc61
https://europepmc.org/articles/PMC10197673/
https://europepmc.org/articles/PMC10197673/
Autor:
Divya Bezwada, Nicholas P. Lesner, Bailey Brooks, Hieu S. Vu, Zheng Wu, Ling Cai, Stacy Kasitinon, Sherwin Kelekar, Feng Cai, Arin B. Aurora, McKenzie Patrick, Ashley Leach, Rashed Ghandour, Yuanyuan Zhang, Duyen Do, Jessica Sudderth, Dennis Dumesnil, Sara House, Tracy Rosales, Alan M. Poole, Yair Lotan, Solomon Woldu, Aditya Bagrodia, Xiaosong Meng, Jeffrey A. Cadeddu, Prashant Mishra, Ivan Pedrosa, Payal Kapur, Kevin D. Courtney, Craig R. Malloy, Vitaly Margulis, Ralph J. DeBerardinis
Publikováno v:
bioRxiv
SummaryMost kidney cancers display evidence of metabolic dysfunction1–4but how this relates to cancer progression in humans is unknown. We used a multidisciplinary approach to infuse13C-labeled nutrients during surgical tumour resection in over 70
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b6d2448d68a99890c9685f4d79bf794
https://doi.org/10.1101/2023.02.06.527285
https://doi.org/10.1101/2023.02.06.527285
Autor:
Sara M Nowinski, Bryn D Webb, Ashley Solmonson, Jaya Ganesh, Richard J Rodenburg, Joao Leandro, Anthony Evans, Hieu S Vu, Thomas P Naidich, Bruce D Gelb, Ralph J DeBerardinis, Jared Rutter, Sander M Houten
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2eca0809127b0bd545585b79311f996a
https://doi.org/10.7554/elife.68047.sa2
https://doi.org/10.7554/elife.68047.sa2
Autor:
Bryn D. Webb, Sara M. Nowinski, Ashley Solmonson, Jaya Ganesh, Richard J. Rodenburg, João Leandro, Anthony Evans, Hieu S. Vu, Thomas P. Naidich, Bruce D. Gelb, Ralph J. DeBerardinis, Jared Rutter, Sander M. Houten
Malonyl-CoA-acyl carrier protein transacylase (MCAT) is an enzyme involved in mitochondrial fatty acid synthesis (mtFAS) and catalyzes the transfer of the malonyl moiety of malonyl-CoA to the mitochondrial acyl carrier protein (ACP). Previously, we s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::800e1a9223f6c1123a27afa3eb90e493
https://doi.org/10.1101/2022.12.06.22283173
https://doi.org/10.1101/2022.12.06.22283173