Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Hiep Huatan"'
Autor:
Martin J. Whitaker, Brian G. Keevil, Hiep Huatan, John Newell-Price, Eleni Daniel, Richard J. Ross, Jo Quirke, Enis Mumdzic, John Porter, Bernard Voet
Publikováno v:
European Journal of Endocrinology
Context There is no licensed oral native testosterone (NT) because of challenges in the formulation. Licensed oral formulations of the ester, testosterone undecanoate (TU), require a meal for absorption and generate supraphysiological dihydrotestoste
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e60cbe85d8b2777df68ec07d4d8d0e46
Autor:
Paul Marcus, Richard Fitzgerald, Laurence Skillern, Lisa Patel, Martyn Foster, Anna Daroszewska, Jim Bush, Rob van't Hof, Andy Gray, Williams Samuel Cameron, Hiep Huatan, Sonya Abraham
Publikováno v:
Poster Presentations.
Background Despite the availability of several treatment options some patients with Rheumatoid Arthritis (RA) fail to benefit and for those who do response rates are similar across therapeutic classes. Thus there remains a need for new therapies with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b766727ab2ef0f85f05e1163ab8baa3c
https://doi.org/10.1136/annrheumdis-2019-eular.2794
https://doi.org/10.1136/annrheumdis-2019-eular.2794
Autor:
Storey David E, Simona Chessa, Pranav Gupta, Hiep Huatan, Jonathan C. Burley, Laura M. Mason, Colin D. Melia
Publikováno v:
International Journal of Pharmaceutics. 510:210-220
The Dynamic Gastric Model (DGM) is an in-vitro system which aims to closely replicate the complex mixing, dynamic biochemical release and emptying patterns of the human stomach. In this study, the DGM was used to understand how the polymer content of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6f4f2f904863b9909f215b7dbc16efb
https://doi.org/10.1016/j.ijpharm.2016.06.034
https://doi.org/10.1016/j.ijpharm.2016.06.034
Autor:
Miguel Debono, Wiebke Arlt, Martin J. Whitaker, Richard J. Ross, Deborah P. Merke, Hiep Huatan
Publikováno v:
Clinical Endocrinology. 80:554-561
SummaryObjective It is not possible with current hydrocortisone replacement to mimic the diurnal cortisol profile in patients with adrenal insufficiency. Previous attempts with modified-release technology were unsuccessful. Our objective was to devel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::629a921eb2e7fc31a02dda5b6dca7476
https://doi.org/10.1111/cen.12316
https://doi.org/10.1111/cen.12316
Autor:
Martin J. Whitaker, Hiep Huatan, Trevor N. Johnson, Heiko Krude, Geoffrey T. Tucker, Oliver Blankenstein, Richard J. Ross, David Eckland, Dena Digweed, Sarah Spielmann
Publikováno v:
The Journal of clinical endocrinology and metabolism. 100(4)
Treatment of neonates and infants with adrenal insufficiency is unsatisfactory because unlicensed hydrocortisone formulations are used.The objectives were to survey current hydrocortisone prescribing practice and develop a novel hydrocortisone formul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6014f63aa4a34fdc7f2acfa75fda556f
https://pubmed.ncbi.nlm.nih.gov/25646792
https://pubmed.ncbi.nlm.nih.gov/25646792
Autor:
R. Hollands, Georgina E. Milroy, Lynn F. Gladden, Ruth E. Cameron, Michael D. Mantle, R.W. Smith, A.S. Clough, Hiep Huatan
Publikováno v:
Polymer. 44:1425-1435
Magnetic resonance imaging (MRI) and scanning microbeam nuclear reaction analysis (NRA) were used to monitor changes of water ingress into polyglycolide (PGA) disks with degradation time. MRI detects H2O, whereas NRA is sensitive to D2O. The acid-cat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e4b46a573f5bffab225a46f0e72bd6ef
https://doi.org/10.1016/s0032-3861(02)00884-4
https://doi.org/10.1016/s0032-3861(02)00884-4
Publikováno v:
Journal of Materials Science: Materials in Medicine. 14:465-473
This paper reports the use of magnetic resonance imaging (MRI) on polyglycolide disks to monitor the change in water ingress with degradation time. Very little response was measured before 13 days, but after this time, water began to penetrate the di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::be5cea5bc22f5680ecc436c240ba9bac
https://doi.org/10.1023/a:1023223220409
https://doi.org/10.1023/a:1023223220409
Autor:
Heiko Krude, Oliver Blankenstein, Dena Digweed, Sarah Spielmann, David Eckland, Richard S. Ross, Martin J. Whitaker, Hiep Huatan
Publikováno v:
Endocrine Abstracts.
Current treatment in Europe for adrenal insufficiency in neonates and infants is unsatisfactory as unlicensed adult dosage formulations are used. These are difficult to administer and may give rise to inconsistencies in dose as the content uniformity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a038b9ebeb33f3f02ef77811f2f78f73
https://doi.org/10.1530/endoabs.35.p30
https://doi.org/10.1530/endoabs.35.p30
Autor:
Richard S. Ross, Wiebke Arlt, Hiep Huatan, Deborah P Merke, Martin J. Whitaker, Miguel Debono
Publikováno v:
Endocrine Abstracts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::55a14a64a8c526a4397abb41a826847e
https://doi.org/10.1530/endoabs.32.p1
https://doi.org/10.1530/endoabs.32.p1
Publikováno v:
Journal of Applied Polymer Science. 89:2937-2939
The melting behavior of polyglycolide (PGA) with eight other biodegradable polymers was investigated to determine whether forming a blend could be used as a method of lowering the melting point of PGA. Blends were prepared by melt processing in diffe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::35f807e4d699df09c4df4cb8fa5c33a0
https://doi.org/10.1002/app.12353
https://doi.org/10.1002/app.12353