Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Hien-Ping Ngo"'
Autor:
Stephen Gregory Addinall, Eva-Maria Holstein, Conor Lawless, Min Yu, Kaye Chapman, A Peter Banks, Hien-Ping Ngo, Laura Maringele, Morgan Taschuk, Alexander Young, Adam Ciesiolka, Allyson Lurena Lister, Anil Wipat, Darren James Wilkinson, David Lydall
Publikováno v:
PLoS Genetics, Vol 7, Iss 4, p e1001362 (2011)
To better understand telomere biology in budding yeast, we have performed systematic suppressor/enhancer analyses on yeast strains containing a point mutation in the essential telomere capping gene CDC13 (cdc13-1) or containing a null mutation in the
Externí odkaz:
https://doaj.org/article/9b28f9f63e7b434e899130efd26f9f54
Autor:
Hien-Ping Ngo, David Lydall
Publikováno v:
PLoS Genetics, Vol 6, Iss 8, p e1001072 (2010)
Maintenance of telomere capping is absolutely essential to the survival of eukaryotic cells. Telomere capping proteins, such as Cdc13 and POT1, are essential for the viability of budding yeast and mammalian cells, respectively. Here we identify, for
Externí odkaz:
https://doaj.org/article/023bfcfffe4a4ffb9e3c797993df7d18
Publikováno v:
PLoS Genetics, Vol 5, Iss 7, p e1000552 (2009)
Polyploidy is frequent in nature and is a hallmark of cancer cells, but little is known about the strategy of DNA repair in polyploid organisms. We have studied DNA repair in the polyploid archaeon Haloferax volcanii, which contains up to 20 genome c
Externí odkaz:
https://doaj.org/article/71ae72d665ec4d45a23803fbf45b7445
Publikováno v:
Molecular Biology of the Cell. 20:1683-1694
Esc2 is a member of the RENi family of SUMO-like domain proteins and is implicated in gene silencing in Saccharomyces cerevisiae. Here, we identify a dual role for Esc2 during S-phase in mediating both intra-S-phase DNA damage checkpoint signaling an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49cb8e9b0cf6eabb0d900dec8fe6c7ee
https://doi.org/10.1091/mbc.e08-08-0877
https://doi.org/10.1091/mbc.e08-08-0877
Autor:
Mikhajlo K. Zubko, Nick Morrice, Amanda Greenall, Hien-Ping Ngo, Isabelle Morin, David Lydall
Publikováno v:
The EMBO Journal
Exo1 is a nuclease involved in mismatch repair, DSB repair, stalled replication fork processing and in the DNA damage response triggered by dysfunctional telomeres. In budding yeast and mice, Exo1 creates single-stranded DNA (ssDNA) at uncapped telom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e2dcb9be6683a86704958bf37b630f9
http://europepmc.org/articles/PMC2532783
http://europepmc.org/articles/PMC2532783
Publikováno v:
Molecular Biology of the Cell. 18:4062-4073
CSM2, PSY3, SHU1, and SHU2 (collectively referred to as the SHU genes) were identified in Saccharomyces cerevisiae as four genes in the same epistasis group that suppress various sgs1 and top3 mutant phenotypes when mutated. Although the SHU genes ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::694247845b8de3935360e46b5c11302b
https://doi.org/10.1091/mbc.e07-05-0490
https://doi.org/10.1091/mbc.e07-05-0490
Publikováno v:
The EMBO Journal. 22:735-745
PriA protein provides a means to load the DnaB replicative helicase at DNA replication fork and D loop structures, and is therefore a key factor in the rescue of stalled or broken forks and subsequent replication restart. We show that the nucleoid-as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::383f41076450299b6c85b69d99c1f39a
https://doi.org/10.1093/emboj/cdg048
https://doi.org/10.1093/emboj/cdg048
Autor:
Alexander I. Young, Min Yu, Morgan Taschuk, Darren J. Wilkinson, Conor Lawless, Hien-Ping Ngo, David Lydall, Laura Maringele, Adam Ciesiolka, Eva-Maria Holstein, Stephen G. Addinall, Allyson L. Lister, A. Peter Banks, Anil Wipat, Kaye Chapman
Publikováno v:
PLoS Genetics
PLoS Genetics, Vol 7, Iss 4, p e1001362 (2011)
PLoS Genetics, Vol 7, Iss 4, p e1001362 (2011)
To better understand telomere biology in budding yeast, we have performed systematic suppressor/enhancer analyses on yeast strains containing a point mutation in the essential telomere capping gene CDC13 (cdc13-1) or containing a null mutation in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa87b054549537091028e953c5529aac
https://pubmed.ncbi.nlm.nih.gov/21490951
https://pubmed.ncbi.nlm.nih.gov/21490951
Publikováno v:
PLoS Genetics, Vol 5, Iss 7, p e1000552 (2009)
PLoS Genetics
PLoS Genetics
Polyploidy is frequent in nature and is a hallmark of cancer cells, but little is known about the strategy of DNA repair in polyploid organisms. We have studied DNA repair in the polyploid archaeon Haloferax volcanii, which contains up to 20 genome c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d20f77bc177fe90eb15d0df9cfb11e2
http://europepmc.org/articles/PMC2700283?pdf=render
http://europepmc.org/articles/PMC2700283?pdf=render
Publikováno v:
Applied and environmental microbiology. 70(2)
Since most archaea are extremophilic and difficult to cultivate, our current knowledge of their biology is confined largely to comparative genomics and biochemistry. Haloferax volcanii offers great promise as a model organism for archaeal genetics, b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::128e5c2fbb711cf3097fff1e8a55eddf
https://pubmed.ncbi.nlm.nih.gov/14766575
https://pubmed.ncbi.nlm.nih.gov/14766575