Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Hideyuki Tomitori"'
Autor:
Kyohei Higashi, Yoshiki Takeuchi, Ann Mukuno, Hideyuki Tomitori, Masaki Miya, Robert J Linhardt, Toshihiko Toida
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0120860 (2015)
Shark fin, used as a food, is a rich source of glycosaminoglyans (GAGs), acidic polysaccharides having important biological activities, suggesting their nutraceutical and pharmaceutical application. A comprehensive survey of GAGs derived from the fin
Externí odkaz:
https://doaj.org/article/728f202e1bb04c76a0ccaccb2b0649f2
Autor:
Mika Hirose, Michio Murata, Satoshi Murakami, Shigeru Sugiyama, Kyohei Higashi, Mayumi Niiyama, Kazuei Igarashi, Hiroyoshi Matsumura, Hideyuki Tomitori, Hiroaki Adachi, Yuma Miyazaki, Kazufumi Takano, Tsuyoshi Inoue, Sae Ishikawa, Keiko Kashiwagi, Yusuke Mori
Publikováno v:
International Journal of Biochemistry & Cell Biology. 76:87-97
Spermidine acetyltransferase (SAT) from Escherichia coli, which catalyses the transfer of acetyl groups from acetyl-CoA to spermidine, is a key enzyme in controlling polyamine levels in prokaryotic cells. In this study, we determined the crystal stru
Autor:
Hiroaki Adachi, Michio Murata, Kazufumi Takano, Tsuyoshi Inoue, Satoshi Murakami, Shigeru Sugiyama, Kazuei Igarashi, Mika Hirose, Keiko Kashiwagi, Yusuke Mori, Mayumi Niiyama, Kyohei Higashi, Hiroyoshi Matsumura, Tomoko Yamashita, Hideyuki Tomitori, Sae Ishikawa
Publikováno v:
Acta Crystallographica Section F-Structural Biology and Crystallization Communications. 69:884-887
The spermidine acetyltransferase (SAT) from Escherichia coli catalyses the transfer of acetyl groups from acetyl-CoA to spermidine. SAT has been expressed and purified from E. coli. SAT was crystallized by the sitting-drop vapour-diffusion method to
Autor:
Hideyuki Tomitori, Mizuho Nakamura, Takehiro Suzuki, Yusuke Terui, Keiko Kashiwagi, Robert A. Casero, Naoshi Dohmae, Kazuei Igarashi, Takeshi Uemura, Akihiko Sakamoto
Publikováno v:
The international journal of biochemistrycell biology. 79
We have shown recently that acrolein is strongly involved in cell damage during brain infarction and chronic renal failure. To study the mechanism of acrolein detoxification, we tried to isolate Neuro2a cells with reduced sensitivity to acrolein toxi
Autor:
Ryotaro Saiki, Yutaka Tamura, Keith Williams, Satomi Mizuno, Hideyuki Tomitori, Keiko Kashiwagi, Kazuhiro Nishimura, Kazuei Igarashi, Akiko Suganami, Yuki Yoshizawa, Toshihiko Toida, Takashi Masuko
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 343:82-90
Modeling the binding sites for spermine and ifenprodil on the regulatory (R) domains of the N -methyl-d-aspartate receptor GluN1 and GluN2B subunits was carried out after measuring spermine stimulation and ifenprodil inhibition at receptors containin
Autor:
Yusuke Terui, Hideyuki Tomitori, Akira Ishihama, Akihiko Sakamoto, Mariko Akiyama, Kaneyoshi Yamamoto, Kazuei Igarashi, Keiko Kashiwagi
Publikováno v:
The International Journal of Biochemistry & Cell Biology. 44:412-422
It is known that polyamines increase cell growth through stimulation of the synthesis of several kinds of proteins encoded by the so-called "polyamine modulon". We recently reported that polyamines also increase cell viability at the stationary phase
Publikováno v:
Amino Acids. 42:733-740
The structure and function of a cadaverine-lysine antiporter CadB and a putrescine-ornithine antiporter PotE in Escherichia coli were evaluated using model structures based on the crystal structure of AdiC, an agmatine-arginine antiporter, and the ac
Ribosome Modulation Factor, an Important Protein for Cell Viability Encoded by the Polyamine Modulon
Autor:
Akira Ishihama, Kyohei Higashi, Kaneyoshi Yamamoto, Hideyuki Tomitori, Kazuei Igarashi, Yusuke Terui, Mariko Akiyama, Yuzuru Tabei, Keiko Kashiwagi
Publikováno v:
Journal of Biological Chemistry. 285:28698-28707
We searched for proteins whose synthesis is enhanced by polyamines at the stationary phase of cell growth using an Escherichia coli polyamine-requiring mutant in which cell viability is greatly decreased by polyamine deficiency. The synthesis of ribo
Autor:
Yuzuru Tabei, Keiko Kashiwagi, Kazuei Igarashi, Yusuke Terui, Akira Ishihama, Kyohei Higashi, Hideyuki Tomitori, Kaneyoshi Yamamoto
Publikováno v:
Journal of Bacteriology. 191:5348-5357
Proteins whose synthesis is enhanced by polyamines at the level of translation were identified with a polyamine-requiring mutant cultured in the presence of 0.1% glucose and 0.02% glutamate at 42°C. Polyamines had a greater effect on cell growth at
Autor:
Yoshiki Machi, Keiko Kashiwagi, Kazuei Igarashi, Madoka Yoshida, Hideyuki Tomitori, Motofumi Hagihara, Kyohei Higashi, Hitomi Goda, Masaru Niitsu, Takeshi Ohya
Publikováno v:
Biochemical and Biophysical Research Communications. 378:313-318
The toxicity of acrolein was compared with that of reactive oxygen species using a mouse mammary carcinoma FM3A cell culture system. Complete inhibition of cell growth was accomplished with 10 microM acrolein, 100 microM H(2)O(2), and 20 microM H(2)O