Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Hideyuki Tominaga"'
Autor:
Ling Wei, Hideyuki Tominaga, Ryuichi Ohgaki, Pattama Wiriyasermkul, Kohei Hagiwara, Suguru Okuda, Kyoichi Kaira, Yukio Kato, Noboru Oriuchi, Shushi Nagamori, Yoshikatsu Kanai
Publikováno v:
Journal of Pharmacological Sciences, Vol 130, Iss 2, Pp 101-109 (2016)
A PET tracer for tumor imaging, 3-18F-l-α-methyl-tyrosine ([18F]FAMT), has advantages of high cancer-specificity and low physiological background. In clinical studies, FAMT-PET has been proved useful for the detection of malignant tumors and their d
Externí odkaz:
https://doaj.org/article/61518fa08cbc499fa5530b8aa1cfbe24
Autor:
Narakorn Khunweeraphong, Shushi Nagamori, Pattama Wiriyasermkul, Yumiko Nishinaka, Printip Wongthai, Ryuichi Ohgaki, Hidekazu Tanaka, Hideyuki Tominaga, Hiroyuki Sakurai, Yoshikatsu Kanai
Publikováno v:
Journal of Pharmacological Sciences, Vol 119, Iss 4, Pp 368-380 (2012)
System L is a major transport system for cellular uptake of neutral amino acids. Among system L transporters, L-type amino acid transporter 1 (LAT1) is responsible for the nutrient uptake in cancer cells, whereas L-type amino acid transporter 2 (LAT2
Externí odkaz:
https://doaj.org/article/b0c960fcf96d4847a58f941dfc229c89
Autor:
Suguru Okuda, Chunhuan Jin, Yasuharu Kawamoto, Hiroki Okanishi, Shushi Nagamori, Yoshikatsu Kanai, Xin He, Hideyuki Tominaga, Ryuichi Ohgaki, Minhui Xu, Ling Wei
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 375:451-462
Halogenated tyrosine/phenylalanine derivatives have been developed for use in tumor imaging and targeted alpha therapy. 3-Fluoro-α-methyl-l-tyrosine (FAMT), targeting amino acid transporter LAT1 (SLC7A5), is a cancer-specific positron emission tomog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::446197debeb5ae3d7fe878b5d8928b86
https://doi.org/10.1124/jpet.120.000235
https://doi.org/10.1124/jpet.120.000235
Publikováno v:
Echinoderms through Time
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bfe7db27cbb79e906869035e64e00be1
https://doi.org/10.1201/9781003077831-87
https://doi.org/10.1201/9781003077831-87
Autor:
Hideyuki Tominaga, Shushi Nagamori, Chunhuan Jin, Ryuichi Ohgaki, Yoshikatsu Kanai, Suguru Okuda
Publikováno v:
Proceedings for Annual Meeting of The Japanese Pharmacological Society. :PO1-8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::40d751dd7382bd7f2d16d0ab86458360
https://doi.org/10.1254/jpssuppl.wcp2018.0_po1-8-40
https://doi.org/10.1254/jpssuppl.wcp2018.0_po1-8-40
Autor:
Kengo Takahashi, Yoshikatsu Kanai, Akira Shimizu, D. Utsumi, Y. Okubo, Masahito Yasuda, Osamu Ishikawa, Hideyuki Tominaga, Noboru Oriuchi, Kyoichi Kaira
Publikováno v:
Neoplasma. 64:283-288
L-type amino acid transporter 1 (LAT1) and CD98 are frequently expressed in various human cancers, and closely correlated with tumor aggressiveness and survival. However, little is known about the expression of LAT1 and CD98 in cutaneous angiosarcoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::467a9ecf3b1be139be0b050ea2ecb44d
https://doi.org/10.4149/neo_2017_216
https://doi.org/10.4149/neo_2017_216
Autor:
Tatsuya Miyazaki, Noriko S. Ishioka, Hideyuki Tominaga, Yoshikatsu Kanai, Noboru Oriuchi, Shushi Nagamori, Aiko Yamaguchi, Kyoichi Kaira, Yoshito Tsushima, Takehiko Yokobori, Hiroyuki Kuwano, Takayuki Asao, Yasuhiro Ohshima
Publikováno v:
Cancer Science
System l amino acid transporter 1 (LAT1) is highly expressed in various types of human cancer, and contributes to cancer growth and survival. Recently, we have shown that LAT1 expression is closely related to the growth and aggressiveness of esophage
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb3bc0133a060c8baf5a6da52a05e77f
https://doi.org/10.1111/cas.13021
https://doi.org/10.1111/cas.13021
Autor:
Kyoichi Kaira, Kohei Hagiwara, Ryuichi Ohgaki, Yoshikatsu Kanai, Ling Wei, Suguru Okuda, Hideyuki Tominaga, Shushi Nagamori, Noboru Oriuchi, Pattama Wiriyasermkul
Publikováno v:
Cancer Science
3-(18)F-l-α-methyl-tyrosine ([18F]FAMT), a PET probe for tumor imaging, has advantages of high cancer-specificity and lower physiologic background. FAMT-PET has been proved useful in clinical studies for the prediction of prognosis, the assessment o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ceb23c9449bf372fc78384ed4f796c4
https://doi.org/10.1111/cas.12878
https://doi.org/10.1111/cas.12878
Autor:
Kohei Hagiwara, Yukio Kato, Shushi Nagamori, Pattama Wiriyasermkul, Ling Wei, Kyoichi Kaira, Ryuichi Ohgaki, Yoshikatsu Kanai, Suguru Okuda, Hideyuki Tominaga, Noboru Oriuchi
Publikováno v:
Journal of Pharmacological Sciences, Vol 130, Iss 2, Pp 101-109 (2016)
A PET tracer for tumor imaging, 3- 18 F- l - α -methyl-tyrosine ([ 18 F]FAMT), has advantages of high cancer-specificity and low physiological background. In clinical studies, FAMT-PET has been proved useful for the detection of malignant tumors and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0522858557a2ae4546e65a1f782e707a
Autor:
Yoshiyuki Hari, Yoshikatsu Kanai, Yasuo Mori, Suguru Okuda, Ryuichi Ohgaki, Shushi Nagamori, Pattama Wiriyasermkul, Hideyuki Tominaga, Naoto Kojima, Shigeki Kiyonaka
Publikováno v:
Amino Acids. 48:1045-1058
Among amino acids, leucine is a potential signaling molecule to regulate cell growth and metabolism by activating mechanistic target of rapamycin complex 1 (mTORC1). To reveal the critical structures of leucine molecule to activate mTORC1, we examine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c70d59faffdb7acfbe91c016bcb04ac
https://doi.org/10.1007/s00726-015-2158-z
https://doi.org/10.1007/s00726-015-2158-z