Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Hideyuki Nishiwaki"'
Publikováno v:
Japanese Journal of Pharmacology. 82:343-349
It is known that mu-agonists inhibit electrical field stimulation (EFS)-evoked ACh release from longitudinal muscle myenteric plexus (LMMP) preparation of guinea pig ileum when muscarinic autoinhibition does not fully work. In the present study, the
Publikováno v:
Journal of Gastroenterology and Hepatology. 14:859-865
Background: Lafutidine ((±)-2-(furfurylsulfinyl)-N-(4-(4-(piperidinomethyl)-2-pyridyl)oxy-(Z)-2-butenyl)acetamide) is a novel histamine H 2 -receptor antagonist and has been shown to exhibit a potent gastroprotective activity in addition to its anti
Publikováno v:
Japanese Journal of Pharmacology. 78:83-86
Endomorphin-1 and -2, putative endogenous ligands for the mu-opioid receptor, inhibited acetylcholine (ACh) release evoked by electrical field stimulation (EFS) at 1 Hz, which partially activates muscarinic autoreceptors, but not at 10 Hz, which full
Publikováno v:
Japanese Journal of Pharmacology. 77:279-286
Relationship between activation of opioid receptors and muscarinic autoinhibition in acetylcholine (ACh) release from the myenteric plexus was studied in longitudinal muscle myenteric plexus (LMMP) preparations of guinea pig ileum. A mu-receptor agon
Publikováno v:
Journal of Gastroenterology and Hepatology. 12:360-367
Pathogenesis of gastric damage induced by non-steroidal anti-inflammatory drugs (NSAID) involves multiple elements, such as deficiency of prostaglandins (PG), gastric hypermotility, neutrophil activation and luminal acid. The present study was perfor
Publikováno v:
Japanese journal of pharmacology. 77(4)
The relationship between muscarinic autoinhibition and the inhibitory effect of morphine on acetylcholine (ACh) release was investigated in a longitudinal muscle with myenteric plexus (LMMP) preparation of guinea pig ileum. Morphine (10 microM) inhib
Inhibitory effects of various spasmolytics on the vagal afferent gastric excitatory response in cats
Autor:
Hideyuki Nishiwaki, Atsushi Kawaguchi, Shunji Aoki, Hisato Kitagawa, Kazuyoshi Kurahashi, Hachiro Usui, Hiroshi Jino, Masatsugu Iwamoto
Publikováno v:
Life sciences. 61(8)
The inhibitory effects of atropine, cimetropium, pirenzepine and N-butylscopolamine on the vagal afferent gastric excitatory response in cats under anesthesia with pentobarbital sodium and infusion of gallamine were examined. Electrical stimulation o
Publikováno v:
Japanese journal of pharmacology. 57(3)
Pathogenesis of duodenal ulcers induced by diethyldithiocarbamate (DDC), a superoxide dismutase (SOD) inhibitor, was investigated in the rat. Repeated s.c. administration of DDC (750 mg/kg) every 12 hr induced duodenal ulcers in the fed rats, and the
Publikováno v:
Digestive diseases and sciences. 35(4)
The effect of baclofen (PCPGABA) on acid secretion, motility, and mucosa was investigated in the anesthetized rat stomach under various body temperatures (BT: 28-38 degrees C), and they were compared with those of 2-deoxy-D-glucose (2DG), an acid sti
Publikováno v:
Digestive diseases and sciences. 35(2)
In anesthetized rats oral administration (2 ml) of both ethanol (50% in 150 mM HCl) and aspirin (80 mM in 150 mM HCl) produced bandlike lesions in the stomach, while more generalized lesions occurred in the pylorus-ligated stomach when the irritant w