Zobrazeno 1 - 10
of 148
pro vyhledávání: '"Hideyuki Mukai"'
Autor:
Marina Miura, Yutaka Miura, Yoshitaka Iwazu, Hideyuki Mukai, Takahiro Sugiura, Yuji Suzuki, Masami Kato, Mayumi Kano, Daisuke Nagata, Kazuhiro Shiizaki, Hiroshi Kurosu, Makoto Kuro-o
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Hyperphosphatemia is a major risk for poor prognosis in patients with end-stage renal disease. However, the molecular mechanism behind this link remains elusive. We and others have demonstrated that serum phosphorus levels correlate positive
Externí odkaz:
https://doaj.org/article/e2060f24832b44d682eb306226d61edb
Autor:
Hideyuki Mukai, Yutaka Miura, Kazuhiko Kotani, Atsushi Kotoda, Hiroshi Kurosu, Toshiyuki Yamada, Makoto Kuro-o, Yoshitaka Iwazu
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract Calciprotein particles (CPPs) are colloids composed of solid-phase calcium-phosphate and serum protein fetuin-A. CPPs form a polydispersed system with different particle size and density. CPPs with specific physical properties can induce cal
Externí odkaz:
https://doaj.org/article/666f25b9276e4875b95681cfdf8104a6
Autor:
Koji Kubouchi, Hideyuki Mukai
Publikováno v:
Biochemistry and Biophysics Reports, Vol 25, Iss , Pp 100895- (2021)
The role of Protein Kinase N2 (PKN2, also known as PRK2/PKNγ) in cell aggregate/spheroid formation in suspension culture was investigated using immortalized fibroblasts established from PKN2flox/flox mouse embryos. PKN2flox/flox cells formed cell ag
Externí odkaz:
https://doaj.org/article/81887a390f754c2db105936b822123a3
Autor:
Hideyuki Mukai, Pei Ming, Bengt Lindholm, Olof Heimbürger, Peter Barany, Peter Stenvinkel, Abdul Rashid Qureshi
Publikováno v:
Kidney & Blood Pressure Research, Vol 43, Iss 2, Pp 522-535 (2018)
Background/Aims: Lung dysfunction associates with increased mortality but the impact of chronic kidney disease (CKD) is less clear. We evaluated lung function and its association with mortality among individuals with normal to severely reduced glomer
Externí odkaz:
https://doaj.org/article/8c5604a53e624ec5966027dd865b357a
Autor:
Rana Mashud, Akira Nomachi, Akihide Hayakawa, Koji Kubouchi, Sally Danno, Takako Hirata, Kazuhiko Matsuo, Takashi Nakayama, Ryosuke Satoh, Reiko Sugiura, Manabu Abe, Kenji Sakimura, Shigeharu Wakana, Hiroyuki Ohsaki, Shingo Kamoshida, Hideyuki Mukai
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-14 (2017)
Abstract Knock-in mice lacking PKN1 kinase activity were generated by introducing a T778A point mutation in the catalytic domain. PKN1[T778A] mutant mice developed to adulthood without apparent external abnormalities, but exhibited lower T and B lymp
Externí odkaz:
https://doaj.org/article/a3d5289eeb8f44ccac821f81a0e78045
Autor:
Hideyuki Mukai, Pei Ming, Bengt Lindholm, Olof Heimbürger, Peter Barany, Björn Anderstam, Peter Stenvinkel, Abdul Rashid Qureshi
Publikováno v:
PLoS ONE, Vol 13, Iss 4, p e0195585 (2018)
Cardiovascular disease (CVD), protein-energy wasting (PEW), and inflammation are common interrelated features of chronic kidney disease (CKD). Less is known about lung dysfunction in CKD and its possible role in this context. We evaluated lung functi
Externí odkaz:
https://doaj.org/article/e327e65ca3184a9ebf85258abf928380
Autor:
Lu Dai, Hideyuki Mukai, Bengt Lindholm, Olof Heimbürger, Peter Barany, Peter Stenvinkel, Abdul Rashid Qureshi
Publikováno v:
PLoS ONE, Vol 12, Iss 12, p e0186659 (2017)
The value of subjective global assessment (SGA) as nutritional assessor of protein-energy wasting (PEWSGA) in chronic kidney disease (CKD) patients depends on its mortality predictive capacity. We investigated associations of PEWSGA with markers of n
Externí odkaz:
https://doaj.org/article/92838775d5ae488ca290ddaae80d1633
Autor:
Shunsuke Uehara, Hideyuki Mukai, Teruhito Yamashita, Masanori Koide, Kohei Murakami, Nobuyuki Udagawa, Yasuhiro Kobayashi
Publikováno v:
Journal of Bone and Mineral Metabolism. 40:251-261
The long-term inhibition of bone resorption suppresses new bone formation because these processes are coupled during physiological bone remodeling. The development of anti-bone-resorbing agents that do not suppress bone formation is urgently needed.
Autor:
Atsushi Kawase, Shunsuke Tateishi, Masahiro Iwaki, Ryosuke Satoh, Hiroaki Shimada, Shintaro Kuroda, Akira Kazaoka, Reiko Sugiura, Hideyuki Mukai
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 379:53-63
In receptor-type transcription factors–mediated cytochrome P450 (P450) induction, few studies have attempted to clarify the roles of protein kinase N (PKN) in the transcriptional regulation of P450s. This study aimed to examine the involvement of P
Autor:
Bengt Lindholm, Xiaomeng Zhang, Zhimin Chen, Abdul Rashid Tony Qureshi, Kristin Danielson, Hideyuki Mukai, Mohamed Suliman, Olof Heimbürger, Jianghua Chen, Peter Stenvinkel, Franz Peter Barany
Publikováno v:
Nephrology Dialysis Transplantation. 37
BACKGROUND AND AIMS Higher mean corpuscular volume (MCV), a measure of the average size of the circulating erythrocyte used for differential diagnosis of anemia or for monitoring macrocytosis, is associated with higher mortality in various clinical s