Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Hideyuki Aizawa"'
Publikováno v:
Clinical Experimental Allergy Reviews. 4:76-81
Summary Eosinophil recruitment and activation are regarded as central to the pathophysiology of allergic diseases, including asthma. An improved understanding of the mechanisms involved in these responses is therefore of great relevance to asthma pat
Autor:
Patricia E. Carrigan, Marc E. Rothenberg, Hideyuki Aizawa, Bruce S. Bochner, James J. Lee, Nives Zimmermann
Publikováno v:
Genomics. 82:521-530
We recently identified a novel human sialic acid binding immunoglobulin-like lectin, Siglec-8, using mRNA from human eosinophils. To search for a mouse Siglec (mSiglec) ortholog of Siglec-8 and other mouse Siglec paralogs, we conducted public databas
Publikováno v:
Blood. 101:5014-5020
Sialic acid binding immunoglobulin-like lectin 8 (Siglec-8), which exists in 2 isoforms including one possessing cytoplasmic tyrosine motifs, is expressed only on human eosinophils, basophils, and mast cells. Until now, its function was unknown. Here
Publikováno v:
Biochemical and biophysical research communications. 218(1)
Ubiquitin-dependent proteolysis is required for cell cycle progression. Here, we demonstrate that the proteasome is activated during in vivo Xenopus egg activation, induced by treatment with the calcium ionophore A23187. It was found that activation
Autor:
Hideyuki Aizawa, Sherry A. Hudson, Bruce S. Bochner, L.H.K. Lim, Paul R. Crocker, H. Tashimoto, Esra Nutku
Publikováno v:
Journal of Allergy and Clinical Immunology. 113:S84
Background The Siglec family of cell surface molecules, of which Siglec-3 (CD33) is a member, shares properties including cytoplasmic ITIM motifs. One member, Siglec-8, has two isoforms, Siglec-8 and Siglec-8L, with the latter expressing ITIMs that c
Publikováno v:
Journal of Allergy and Clinical Immunology. 109:176
Publikováno v:
Journal of Allergy and Clinical Immunology. 109:S225-S225