Zobrazeno 1 - 10
of 105
pro vyhledávání: '"Hideyuki, Yanai"'
Autor:
Junko Nishio, Hideo Negishi, Mika Yasui-Kato, Shoji Miki, Kazuhiko Miyanaga, Kotaro Aoki, Takuma Mizusawa, Masami Ueno, Akira Ainai, Masafumi Muratani, Sho Hangai, Hideyuki Yanai, Hideki Hasegawa, Yoshikazu Ishii, Yasunori Tanji, Tadatsugu Taniguchi
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Increase of the enteric bacteriophages (phage), components of the enteric virome, has been associated with the development of inflammatory bowel diseases. However, little is known about how a given phage contributes to the regulation of inte
Externí odkaz:
https://doaj.org/article/388e94e5cf9a4d46be0403bc809bfe9a
Autor:
Wataru Kawase, Daisuke Kurotaki, Yuta Suzuki, Hiroshi Ishihara, Tatsuma Ban, Go R. Sato, Juri Ichikawa, Hideyuki Yanai, Tadatsugu Taniguchi, Kappei Tsukahara, Tomohiko Tamura
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 25, Iss , Pp 708-715 (2021)
RNA interference-based gene silencing drugs are attracting attention for treating various diseases. Lipid nanoparticles (LNPs) are carriers that efficiently deliver small interfering RNA (siRNA) to the cytoplasm of target cells. Recently, we develope
Externí odkaz:
https://doaj.org/article/fa32f02bafe74885ab7b0205c2666905
Autor:
Tatsuma Ban, Masako Kikuchi, Go R. Sato, Akio Manabe, Noriko Tagata, Kayo Harita, Akira Nishiyama, Kenichi Nishimura, Ryusuke Yoshimi, Yohei Kirino, Hideyuki Yanai, Yoshiko Matsumoto, Shuichi Suzuki, Hiroe Hihara, Masashi Ito, Kappei Tsukahara, Kentaro Yoshimatsu, Tadashi Yamamoto, Tadatsugu Taniguchi, Hideaki Nakajima, Shuichi Ito, Tomohiko Tamura
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
IRF5 is a potential target for therapy in systemic lupus erythematosus (SLE). Here the authors show using mouse SLE-like models that genetic or chemical inhibition of IRF5 after SLE onset could be more effective than, or an add on for, currently util
Externí odkaz:
https://doaj.org/article/bdb59bea8b1b42119ff3a063d9c303ba
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Dying or damaged cells that are not completely eradicated by the immune system release their intracellular components in the extracellular space. Aberrant exposure of the damage-associated molecules to the immune system is often associated w
Externí odkaz:
https://doaj.org/article/22d60bea34a74a2f9e372f6b97c7a09b
Autor:
Tatsuma Ban, Daisuke Kurotaki, Kappei Tsukahara, Hiroshi Ishihara, Tadatsugu Taniguchi, Hideyuki Yanai, Wataru Kawase, Tomohiko Tamura, Go R. Sato, Yuta Suzuki, Juri Ichikawa
Publikováno v:
Molecular Therapy. Nucleic Acids
Molecular Therapy: Nucleic Acids, Vol 25, Iss, Pp 708-715 (2021)
Molecular Therapy: Nucleic Acids, Vol 25, Iss, Pp 708-715 (2021)
RNA interference-based gene silencing drugs are attracting attention for treating various diseases. Lipid nanoparticles (LNPs) are carriers that efficiently deliver small interfering RNA (siRNA) to the cytoplasm of target cells. Recently, we develope
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95585f8ea73da77037d699fd05bc3d6c
http://id.nii.ac.jp/1246/00002278/
http://id.nii.ac.jp/1246/00002278/
Publikováno v:
International Immunology. 33:841-846
As clinically demonstrated by the success of immunotherapies to improve survival outcomes, tumors are known to gain a survival advantage by circumventing immune surveillance. A defining feature of this is the creation and maintenance of a tumor immun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d21b66455362a6d1fd61753696e8b015
https://doi.org/10.1093/intimm/dxab050
https://doi.org/10.1093/intimm/dxab050
Autor:
Hideyuki Yanai, Daisuke Yamamoto, Kazuhiko Koike, Ching-Yun Chang, Tatsuhiko Kodama, Sho Hangai, Masanobu Oshima, Sana Hibino, Takeshi Kawamura, Hiroko Oshima, Yousuke Nakai, Ryosuke Tateishi, Tadatsugu Taniguchi, Kyoji Moriya, Yoshitaka Kimura
Publikováno v:
Nature Immunology. 22:947-957
One of most challenging issues in tumor immunology is a better understanding of the dynamics in the accumulation of myeloid-derived suppressor cells (MDSCs) in the tumor microenvironment (TIME), as this would lead to the development of new cancer the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7543c14999072755a25b49254891dae7
https://doi.org/10.1038/s41590-021-00967-5
https://doi.org/10.1038/s41590-021-00967-5
Autor:
Ryusuke Yoshimi, Tadatsugu Taniguchi, Hideyuki Yanai, Shuichi Suzuki, Akira Nishiyama, Hideaki Nakajima, Tadashi Yamamoto, Shuichi Ito, Kappei Tsukahara, Yohei Kirino, Noriko Tagata, Go R. Sato, Kenichi Nishimura, Tatsuma Ban, Hiroe Hihara, Masako Kikuchi, Akio Manabe, Masashi Ito, Kentaro Yoshimatsu, Yoshiko Matsumoto, Kayo Harita, Tomohiko Tamura
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Nature Communications
Nature Communications
The transcription factor IRF5 has been implicated as a therapeutic target for the autoimmune disease systemic lupus erythematosus (SLE). However, IRF5 activation status during the disease course and the effects of IRF5 inhibition after disease onset
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9734fab3dd519fa22dfd9589ad1d66db
https://doaj.org/article/bdb59bea8b1b42119ff3a063d9c303ba
https://doaj.org/article/bdb59bea8b1b42119ff3a063d9c303ba
Publikováno v:
Cancer Science
The signal‐transducing innate receptors represent classes of pattern recognition receptors (PRRs) that play crucial roles in the first line of the host defense against infections by the recognition of pathogen‐derived molecules. Because of their
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85b98dc724af449918ddf7b75b29bfd3
http://europepmc.org/articles/PMC8253268
http://europepmc.org/articles/PMC8253268
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Scientific Reports
Scientific Reports
Dying or damaged cells that are not completely eradicated by the immune system release their intracellular components in the extracellular space. Aberrant exposure of the damage-associated molecules to the immune system is often associated with infla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ffa16c07f7ff0e1e2568fa74d649895
https://doaj.org/article/22d60bea34a74a2f9e372f6b97c7a09b
https://doaj.org/article/22d60bea34a74a2f9e372f6b97c7a09b