Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Hideyuki, Ohzawa"'
Autor:
Yurie Futoh, Hideyo Miyato, Hironori Yamaguchi, Misaki Matsumiya, Rei Takahashi, Yuki Kaneko, Yuki Kimura, Hideyuki Ohzawa, Naohiro Sata, Joji Kitayama, Yoshinori Hosoya
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract The vagus nerve is the only pathway for transmitting parasympathetic signals between the brain and thoracoabdominal organs, thereby exhibiting anti-inflammatory functions through the cholinergic anti-inflammatory pathway. Despite often being
Externí odkaz:
https://doaj.org/article/62220152ec8f48409f193568979cdcee
Autor:
Yuki Kaneko, Hideyo Miyato, Mineyuki Tojo, Yurie Futoh, Kazuya Takahashi, Yuki Kimura, Akira Saito, Hideyuki Ohzawa, Hironori Yamaguchi, Naohiro Sata, Joji Kitayama, Yoshinori Hosoya
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract The spleen is a key source of circulating and tumor-infiltrating immune cells. However, the effect of splenectomy on tumor growth remains unclear. At 3 weeks after splenectomy, we subcutaneously injected LuM1 cells into BALB/c mice and evalu
Externí odkaz:
https://doaj.org/article/3225aa42bca945ea975c20178115191b
Autor:
Mineyuki Tojo, Hideyo Miyato, Koji Koinuma, Hisanaga Horie, Hidenori Tsukui, Yuki Kimura, Yuki Kaneko, Hideyuki Ohzawa, Hironori Yamaguchi, Kotaro Yoshimura, Alan Kawarai Lefor, Naohiro Sata, Joji Kitayama
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Although preoperative chemoradiation therapy can down-stage locally advanced rectal cancer (LARC), it has little effect on distant metastases. Metformin exerts an anti-cancer effect partly through the activation of host immunity. LuM1, a hig
Externí odkaz:
https://doaj.org/article/176f0ad991ae4e838affb49ae3c9d4d7
Autor:
Yuki Kimura, Hideyuki Ohzawa, Hideyo Miyato, Yuki Kaneko, Akira Saito, Kazuya Takahashi, Mineyuki Tojo, Hironori Yamaguchi, Kentaro Kurashina, Shin Saito, Yoshinori Hosoya, Alan Kawarai Lefor, Naohiro Sata, Joji Kitayama
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Peritoneal dissemination is a major metastatic pathway for gastrointestinal and ovarian malignancies. The miR-29b family is downregulated in peritoneal fluids in patients with peritoneal metastases (PM). We examined the effect of miR-29b on
Externí odkaz:
https://doaj.org/article/72b27eac0d944d2cbb2266a86b476be8
Autor:
Kazuya Takahashi, Kentaro Kurashina, Hironori Yamaguchi, Rihito Kanamaru, Hideyuki Ohzawa, Hideyo Miyato, Shin Saito, Yoshinori Hosoya, Alan Kawarai Lefor, Naohiro Sata, Joji Kitayama
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
BackgroundThe peritoneal cavity contains many site-specific immune cells which constitute a unique immune microenvironment. However, it is unclear how the local immune signature is altered in patients with peritoneal metastases (PM).MethodsPeritoneal
Externí odkaz:
https://doaj.org/article/243c4fc17cd44c9483f59cd5ccdac816
Autor:
Kohei Tamura, Hideyo Miyato, Rihito Kanamaru, Ai Sadatomo, Kazuya Takahashi, Hideyuki Ohzawa, Takahiro Koyanagi, Yasushi Saga, Yuji Takei, Hiroyuki Fujiwara, Alan Kawarai Lefor, Naohiro Sata, Joji Kitayama
Publikováno v:
Heliyon, Vol 8, Iss 6, Pp e09730- (2022)
Purpose: Although neutrophil extracellular traps (NETs) are present in various tumors, their roles in tumor biology have not been clarified yet. In this study, we examined how NETs affect the pharmacokinetics and effects of doxorubicin (DOX). Methods
Externí odkaz:
https://doaj.org/article/1b9d2147deb4475da355a6d7062498dc
Autor:
Hidenori Tsukui, Hisanaga Horie, Koji Koinuma, Hideyuki Ohzawa, Yasunaru Sakuma, Yoshinori Hosoya, Hironori Yamaguchi, Kotaro Yoshimura, Alan Kawarai Lefor, Naohiro Sata, Joji Kitayama
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-12 (2020)
Abstract Background Anti-tumor effects of radiation therapy (RT) largely depend on host immune function. Adenosine with its strong immunosuppressive properties is an important immune checkpoint molecule. Method We examined how intra-tumoral adenosine
Externí odkaz:
https://doaj.org/article/2e7aeadcb3f7454a9eb2bb941dfabb31
Autor:
Hideyuki Ohzawa, Yuko Kumagai, Hironori Yamaguchi, Hideyo Miyato, Yasunaru Sakuma, Hisanaga Horie, Yoshinori Hosoya, Alan Kawarai Lefor, Naohiro Sata, Joji Kitayama
Publikováno v:
Annals of Gastroenterological Surgery, Vol 4, Iss 1, Pp 84-93 (2020)
Abstract Aim Peritoneal metastases (PM) frequently occur in patients with gastric cancer and result in a poor prognosis. Exosomes play pivotal roles in tumor metastasis through the transfer of microRNAs (miRNAs). We examined the exosomal miRNA profil
Externí odkaz:
https://doaj.org/article/f4858ab94f7842069feb3c74347fcfc0
Autor:
Akira Saito, Mineyuki Tojo, Yuko Kumagai, Hideyuki Ohzawa, Hironori Yamaguchi, Hideyo Miyato, Ai Sadatomo, Daishi Naoi, Gaku Ota, Koji Koinuma, Hisanaga Horie, Alan Kawarai Lefor, Naohiro Sata, Joji Kitayama
Publikováno v:
Heliyon, Vol 7, Iss 1, Pp e05880- (2021)
Aim: PD-1/PD-L1 blockade therapy is now widely used for the treatment of advanced malignancies. Although PD-L1 is known to be expressed by various host cells as well as tumor cells, the role of PD-L1 on non-malignant cells and its clinical significan
Externí odkaz:
https://doaj.org/article/b735ea30c5e041da976d4be6f412a970
Autor:
Atsushi, Miki, Yasunaru, Sakuma, Hideyuki, Ohzawa, Akira, Saito, Yoshiyuki, Meguro, Jun, Watanabe, Kazue, Morishima, Kazuhiro, Endo, Hideki, Sasanuma, Atsushi, Shimizu, Alan Kawarai, Lefor, Yoshikazu, Yasuda, Naohiro, Sata
Publikováno v:
World Journal of Gastroenterology. 28:5614-5625
Estimation of the functional reserve of the remnant liver is important to reduce morbidity and mortality.To estimate the functional reserve of the remnant liver in patients with hepatocellular carcinoma (HCC).We reviewed the medical records of 199 pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da1849163bf0dab0cd71e777bb450a42
https://doi.org/10.3748/wjg.v28.i38.5614
https://doi.org/10.3748/wjg.v28.i38.5614