Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Hideyuki, Mizumachi"'
Publikováno v:
Regenerative Therapy, Vol 15, Iss , Pp 236-242 (2020)
Introduction: Growth factors are crucial bioactive molecules in vitro and in vivo. Among them, basic fibroblast growth factor (bFGF) has been used widely for various applications such as cell culture and regenerative medicine. However, bFGF has extre
Externí odkaz:
https://doaj.org/article/f8deba3ed76342fa8b15973664839fef
Publikováno v:
Regenerative Therapy
Regenerative Therapy, Vol 15, Iss, Pp 236-242 (2020)
Regenerative Therapy, Vol 15, Iss, Pp 236-242 (2020)
Introduction Growth factors are crucial bioactive molecules in vitro and in vivo. Among them, basic fibroblast growth factor (bFGF) has been used widely for various applications such as cell culture and regenerative medicine. However, bFGF has extrem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03ab25476b85b8a0e726834a1232f3f6
https://doi.org/10.1016/j.reth.2020.10.002
https://doi.org/10.1016/j.reth.2020.10.002
Autor:
Masaaki Miyazawa, Raja S. Settivari, Matthew J. LeBaron, Mary Sue Marty, Hideyuki Mizumachi, Hitoshi Sakaguchi
Publikováno v:
Journal of Applied Toxicology. 41:915-927
The regulatory community is transitioning to the use of nonanimal methods for dermal sensitization assessments; however, some in vitro assays have limitations in their domain of applicability depending on the properties of chemicals being tested. Thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0ec2e50c7b2a3ff8a44261f1c221e5a
https://doi.org/10.1002/jat.4076
https://doi.org/10.1002/jat.4076
Autor:
Kazutoshi Saito, Masaaki Miyazawa, Taku Nishijo, Hideyuki Mizumachi, Hitoshi Sakaguchi, Yuki Otsubo
Publikováno v:
The Journal of Toxicological Sciences. 45:57-67
Skin sensitization is a key adverse effect to be addressed during hazard identification and risk assessment of chemicals, because it is the first step in the development of allergic contact dermatitis. Multiple non-animal testing strategies incorpora
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b425d45a227759725fe6773d0c4f7467
https://doi.org/10.2131/jts.45.57
https://doi.org/10.2131/jts.45.57
Autor:
Taku Nishijo, Masaaki Miyazawa, Kazutoshi Saito, Yuki Otsubo, Hitoshi Sakaguchi, Hideyuki Mizumachi
Publikováno v:
The Journal of Toxicological Sciences. 44:13-21
Cosmetic ingredients are often complex mixtures from natural sources such as botanical extracts that might contain minute amounts of constituents with sensitizing potential. The sensitivity of in vitro skin sensitization test methods such as Keratino
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::86438fa9ebcc7ee9b2525d54e6a8cd0f
https://doi.org/10.2131/jts.44.13
https://doi.org/10.2131/jts.44.13
Autor:
Kazutoshi Saito, Hitoshi Sakaguchi, Taku Nishijo, Hideyuki Mizumachi, Yuki Otsubo, Masaaki Miyazawa
Publikováno v:
The Journal of Toxicological Sciences. 44:23-34
Cosmetic ingredients often comprise complex mixtures, such as botanical extracts, which may contain skin sensitizing constituents. In our previous study for the sensitivity of the evaluations of skin sensitizing constituents in mixtures using the bin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::047685552f39d7374defed17d2b39b7a
https://doi.org/10.2131/jts.44.23
https://doi.org/10.2131/jts.44.23
Autor:
Kazutoshi Saito, Megumi Sakuma, Mayu Ikezumi, Mika Watanabe, Hiroko Motohashi, Midori Takeyoshi, Masaaki Miyazawa, Noriyasu Imai, Hideyuki Mizumachi, Asami Umetsu, Hiroko Okutomi
Publikováno v:
Journal of Applied Toxicology. 38:1233-1243
The epidermal sensitization assay (EpiSensA) is an in vitro skin sensitization test method based on gene expression of four markers related to the induction of skin sensitization; the assay uses commercially available reconstructed human epidermis. E
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::28fcac7196d38f009fcd72e614656243
https://doi.org/10.1002/jat.3634
https://doi.org/10.1002/jat.3634
Autor:
Yuki Otsubo, Masaaki Miyazawa, Taku Nishijo, Hideyuki Mizumachi, Kazutoshi Saito, Hitoshi Sakaguchi
Publikováno v:
Regulatory Toxicology and Pharmacology. 88:118-124
Skin sensitization is one of the key safety endpoints for chemicals applied directly to the skin. Several integrated testing strategies (ITS) using multiple non-animal test methods have been developed to accurately evaluate the sensitizing potential
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b29c51a31b27b0553529ebc34f73ec70
https://doi.org/10.1016/j.yrtph.2017.06.002
https://doi.org/10.1016/j.yrtph.2017.06.002
Autor:
Taku, Nishijo, Masaaki, Miyazawa, Kazutoshi, Saito, Yuki, Otsubo, Hideyuki, Mizumachi, Hitoshi, Sakaguchi
Publikováno v:
The Journal of toxicological sciences. 44(1)
Cosmetic ingredients are often complex mixtures from natural sources such as botanical extracts that might contain minute amounts of constituents with sensitizing potential. The sensitivity of in vitro skin sensitization test methods such as Keratino
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0c535edb628f08c410c56ae53ce64587
https://pubmed.ncbi.nlm.nih.gov/30626776
https://pubmed.ncbi.nlm.nih.gov/30626776
Autor:
Taku, Nishijo, Masaaki, Miyazawa, Kazutoshi, Saito, Yuki, Otsubo, Hideyuki, Mizumachi, Hitoshi, Sakaguchi
Publikováno v:
The Journal of toxicological sciences. 44(1)
Cosmetic ingredients often comprise complex mixtures, such as botanical extracts, which may contain skin sensitizing constituents. In our previous study for the sensitivity of the evaluations of skin sensitizing constituents in mixtures using the bin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4ed904e58c378de7487f0ee1d0154170
https://pubmed.ncbi.nlm.nih.gov/30626777
https://pubmed.ncbi.nlm.nih.gov/30626777