Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Hideya Igarashi"'
Publikováno v:
Clinical Immunology. 150:12-21
We previously reported that somatic mutations in the p53 gene accumulated at a higher frequency in AID(activation induced cytidine deaminase)(+) RA-FLS, which may result in the malfunction of p53, causing the tumor-like properties of RA-FLS. Among th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b4a505a76acc21b4e1ac5a50ee9aeed
https://doi.org/10.1016/j.clim.2013.10.013
https://doi.org/10.1016/j.clim.2013.10.013
Autor:
Kazuhiko Kuwahara, Sachiko Hirose, Teppei Toda, Mareki Ohtsuji, Nobuo Sakaguchi, Masahiro Kitabatake, Hideya Igarashi, Hiromichi Tsurui
Publikováno v:
The Journal of Immunology. 189:1193-1201
To investigate signals that control B cell selection, we examined expression of G5PR, a regulatory subunit of the serine/threonine protein phosphatase 2A, which suppresses JNK phosphorylation. G5PR is upregulated in activated B cells, in Ki67-negativ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96b1ea241eed8e483f39f729876f2eec
https://doi.org/10.4049/jimmunol.1102774
https://doi.org/10.4049/jimmunol.1102774
Autor:
Taro Saika, Hideki Yoshikawa, Jun Hashimoto, Ayano Yahagi, Katsuhiko Ishihara, Hideya Igarashi, Tetsuya Tomita
Publikováno v:
Immunology Letters. 141:246-253
Circuit of chronic inflammation in the joints of rheumatoid arthritis (RA) starts from the production of inflammatory cytokines by fibroblast-like synoviocytes (FLS) stimulated by TNFα produced by inflammatory cells mainly composed of macrophages. I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53f2fa50d3df692c4534b03b0e260281
https://doi.org/10.1016/j.imlet.2011.10.011
https://doi.org/10.1016/j.imlet.2011.10.011
Publikováno v:
Biochemical and Biophysical Research Communications. 340:338-346
BCR-crosslinking triggers activation-induced cell death (AICD) selectively in the restricted stage of B-cell differentiation. We examined the transcription of a protein phosphatase subunit G5PR in immature and mature B-cells, because absence of this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4ef85aee38729125b14026dbe5e3dbd
https://doi.org/10.1016/j.bbrc.2005.11.169
https://doi.org/10.1016/j.bbrc.2005.11.169
Autor:
Ayano Yahagi, Taro Saika, Hiroyasu Hirano, Miwa Takai-Imamura, Fumio Tsuji, Hiroyuki Aono, Masanori Iseki, Yoshitaka Morita, Hideya Igarashi, Yukihiko Saeki, Katsuhiko Ishihara
Publikováno v:
RMD Open; 6/21/2019, Vol. 5, p1-11, 11p
Autor:
Hideya Igarashi, Kay L. Medina, Takafumi Yokota, Maria Isabel D. Rossi, Nobuo Sakaguchi, Philip C. Comp, Paul W. Kincade
Publikováno v:
International Immunology. 17:501-511
Glucocorticoids are extensively used in anti-inflammatory therapy and may contribute to the normal regulation of lymphopoiesis. This study utilized new information about the early stages of lymphopoiesis in mouse and man to determine precisely which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa7a9979135bc2f496cbf0aa40127ee0
https://doi.org/10.1093/intimm/dxh230
https://doi.org/10.1093/intimm/dxh230
Publikováno v:
The Journal of Experimental Medicine
B cell receptor (BCR) cross-linking induces B cell proliferation and sustains survival through the phosphorylation-dependent signals. We report that a loss of the protein phosphatase component G5PR increased the activation-induced cell death (AICD) a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59339d99d6da3511c464e483be1a20c7
http://europepmc.org/articles/PMC2212881
http://europepmc.org/articles/PMC2212881
Autor:
Tohru Funahashi, Yuji Matsuzawa, Kenji Oritani, Masahiko Takahashi, Yoshiaki Tomiyama, Takafumi Yokota, Hideya Igarashi, Kay L. Medina, Paul W. Kincade, C. S. Reddy Meka, Taku Kouro
Publikováno v:
The Journal of Immunology. 171:5091-5099
Adiponectin, an adipocyte-derived hormone, is attracting considerable interest as a potential drug for diabetes and obesity. Originally cloned from human s.c. fat, the protein is also found in bone marrow fat cells and has an inhibitory effect on adi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a98abcf00983df6ef167ec447ff09165
https://doi.org/10.4049/jimmunol.171.10.5091
https://doi.org/10.4049/jimmunol.171.10.5091
Autor:
Hideya Igarashi, Nobuo Sakaguchi, Takafumi Yokota, Taku Kouro, John J.T. Owen, Jun Hirose, Paul W. Kincade, Sophia C. Gregory, Karla P. Garrett
Publikováno v:
Immunity. 19:365-375
RAG1/GFP knockin mice were exploited to isolate and characterize fetal lymphoid progenitors. CD11b and IL-7Rα are expressed in a developmental stage-dependent fashion, revealing how substantial numbers of early lymphoid progenitors were discarded or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::915f2c2959bf67289c8b273da18aaca7
https://doi.org/10.1016/s1074-7613(03)00231-0
https://doi.org/10.1016/s1074-7613(03)00231-0
Publikováno v:
Immunological Reviews. 189:28-40
The earliest progenitors of lymphocytes are extremely rare and typically present among very complex populations of hematopoietic cells. Additionally, it is difficult to know how cells with any given set of characteristics are developmentally related
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9187a7c8a518bc4de330832e94232865
https://doi.org/10.1034/j.1600-065x.2002.18904.x
https://doi.org/10.1034/j.1600-065x.2002.18904.x