Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Hidetsugu Otsuka"'
Autor:
Hidetsugu Otsuka-Murakami, Wei Liu, Michiko Fujita, Yoshihiro Hotta, Toshiki Masumizu, Michio Yajima, Norio Kawai, Naohisa Ishikawa, Junichi Nakagawa, Masahiro Kohno
Publikováno v:
European Journal of Pharmacology. 380:37-48
In guinea-pig myocardial mitochondria preparation, lowering the Ca2+ concentration or pH level in the perfusate rapidly elevated the fura-2 Ca2+ signal ([Ca2+]m). Pretreatment with 10(-4) M L-Arg inhibited the rapid [Ca2+]m influx, whereas administra
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology. 1040:260-266
After phorbol 12-myristate 13-acetate (PMA) stimulation the increase of NADPH:nitroblue tetrazolium reductase activity in the plasma membrane almost corresponded with the stimulated activity of respiratory burst oxidase. Solubilization of plasma memb
Autor:
Tomohiro Takeo, Yoshihiro Hotta, Michio Yajima, Norio Kawai, Naohisa Ishikawa, Kazuto Yamada, Lei Huang, Naohito Ohashi, Hidetsugu Otsuka-Murakami, Haruaki Nishimaki, Kazuki Matsui, Gen Itoh, Setsuko Yamamoto
Publikováno v:
European journal of pharmacology. 503(1-3)
The protective effects of the Na+-H+ exchange (NHE) inhibitors SM-198110 (2-[[(aminoiminomethyl) amino] carbonyl]-4-chloro-1H-indole-1-propanesulfonic acid monohydrate) and SM-197378 (N-(aminoiminomethyl)-1-methyl-7-(sulfooxy)-4-(trifluoromethyl)-1H-
Publikováno v:
Journal of biochemistry. 108(5)
A soluble protein containing very weak NADPH-dependent nitroblue tetrazolium reductase activity was partially purified from the cytosol of dormant human neutrophils by DEAE-5PW ion exchange chromatography. This preparation of cytosolic reductase exhi
Publikováno v:
The Journal of Biochemistry. 84:687-696
A new pathway of NAD+ synthesis from anthranilic acid was found in the livers of rats. Starting from [carboxyl-14C]anthranilic acid, radioactive NAD+ and NADP+ were produced as judged by Dowex-1 X 8-formate column chromatography followed by radiochro
Publikováno v:
The Journal of Biochemistry. 88:987-994
Kynureninase [L-kynurenine hydrolase EC 3.7.1.3] has been purified 614-fold from rat liver cytosol. The purification procedure involved pH treatment, ammonium sulfate fractionation, Sephadex G-100 gel filtration, DEAE-Sepharose CL-6B chromatography,
Publikováno v:
FEBS Letters. (2-3):206-210
NADPH diaphorase activity was found in membrane of DMSO-induced differentiated human promyelocytic leukemia HL-60 cells. This membrane-bound diaphorase activity increased dramatically during differentiation of HL-60 cells. A dye reductase was extract
Publikováno v:
Biochemistry. 27(16)
Upon incubation of detergent-solubilized NADPH-cytochrome P-450 reductase and either cytochrome b5 or cytochrome c in the presence of a water-soluble carbodiimide, a 1-ethyl-3-[3-(dimethylamino)propyl]carbodiimide (EDC), covalently cross-linked compl
Publikováno v:
Biochimica et biophysica acta. 629(1)
In in vivo experiments, radioactivity from [U-14C]GTP was incorporated into biopterin, and, in fact, all carbon atoms of biopterin synthesized in Ascaris lu lumbricoides suum originated from GTP. Biopterin was also biosynthesized in homogenates of ti
Publikováno v:
Biochimica et biophysica acta. 743(3)
Kynurenine aminotransferase (L-kynurenine:2-oxoglutarate aminotransferase (cyclizing), EC 2.6.1.7) was purified 378-fold from rat liver mitochondria by digitonin solubilization, heat treatment, DEAE-Sepharose CL-6B chromatography, Sephadex G-100 gel