Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Hidetsugu, Mihara"'
Autor:
Yasuo Morishima, Hidetsugu Mihara, Keitaro Tsushita, Kazuhito Yamamoto, Hiroshi Kimura, Kiyotaka Kuzushima, Yoshitoyo Kagami, Satoko Morishima, Masafumi Ito, Nobuhiko Emi, Suzuko Moritani, Hirokazu Nagai, Hiroshi Onoda, K Miyamura, Shigeo Nakamura, Tomohiro Kinoshita, Hidemasa Miyauchi, Yasushi Yatabe, Sachiko Iba, Masataka Okamoto, Seiko Iwata, Kaneyuki Ohbayashi, Isamu Sugiura
Publikováno v:
Leukemia & Lymphoma. 56:1072-1078
The immunological status of patients with Epstein-Barr virus-positive diffuse large B-cell lymphoma (EBV+ DLBCL) without obvious immunodeficiency has not been elucidated. A multicenter prospective study was conducted to assess pretreatment T-cell res
Autor:
Hidetsugu Mihara, Hidesuke Yamamoto, Norikazu Tsunekawa-Imai, Mayuko Gotou, Masakazu Nitta, Hiroshi Miwa, Ichiro Hanamura, Miyuki Takahashi, Shohei Mizuno, Akira Imamura, Mineaki Goto, Motohiro Wakabayashi, Motonori Mizutani, Tomohiro Horio, Takamasa Ishikawa, Masato Shikami, Masaya Watarai
Publikováno v:
Oncology Reports. 29:2053-2057
The shift in energy metabolism from oxidative phosphorylation to glycolysis can serve as a target for the inhibition of cancer growth. Here, we examined the metabolic changes induced by 2-deoxyglucose (2-DG), a glycolysis inhibitor, in leukemia cells
Autor:
Masakazu Nitta, Akiko Hattori, Emi Tajima, Akira Imamura, Hiroshi Miwa, Kazuhisa Miura, Toshiko Ikai, Atsushi Satoh, Hidesuke Yamamoto, Masato Shikami, Masato Itoh, Yoshiro Katoh, Kazuhiro Nishii, Norikazu Imai, Akihito Hiramatsu, Hidetsugu Mihara
Publikováno v:
European Journal of Haematology. 75:273-279
Vascular endothelial growth factor (VEGF) and its associated molecule, placenta growth factor (PlGF) are now known to support normal hematopoiesis, and leukemia cell growth. In this study, expression of VEGF and PlGF in acute lymphoblastic leukemia (
Autor:
Hidetsugu Mihara, Norikazu Imai, Hidesuke Yamamoto, Akihito Hiramatsu, Kazuhisa Miura, Hiroshi Miwa, Masakazu Nitta, Yoshiro Kato, Masato Shikami, Atsushi Satoh, Emi Tajima, Toshiko Ikai, Motohiro Wakabayashi, Akira Imamura, Masato Ito
Publikováno v:
Internal Medicine. 43:74-78
We report a case of acute promyelocytic leukemia (APL) with drug-induced hypersensitivity syndrome associated with Epstein-Barr virus (EBV) infection. A 33-year-old woman was admitted because of APL. After complete remission was obtained with the use
Autor:
Norikazu Imai, Yoshiro Kato, Masakazu Nitta, Kazuto Suganuma, Hiroshi Miwa, Akira Imamura, Hidetsugu Mihara, Akiko Hattori, Masaya Watarai, Atsushi Satoh
Publikováno v:
Nihon Naika Gakkai Zasshi. 94:2606-2608
HIV陽性のため当院を紹介された31歳男性.入院後HAART (AZT, 3TC, NFV)療法を開始. 4病日に間質性肺炎を合併し,ステロイドパルス療法施行. 14病日,サイトメガロウイルス(CMV)抗原陽性のためガン
Autor:
Masakazu Nitta, Ichiro Hanamura, Motonori Mizutani, Mayuko Gotou, Hidetsugu Mihara, Kazuto Suganuma, Norikazu Tsunekawa-Imai, Mineaki Goto, Hiroshi Miwa, Akira Imamura, Masaya Watarai, Hidesuke Yamamoto, Motohiro Wakabayashi, Miyuki Takahashi, Hiroko Komatsubara, Shohei Mizuno, Tomohiro Horio, Masato Shikami
Publikováno v:
Leukemia research. 37(9)
We examined the effects of diet nutrients on xenotransplanted leukemia cells, THP-1 or NB4. THP-1 tumors showed more growth when fed with high fat diet, while NB4 tumors grew more with high carbohydrate diet. Then, administration of 2-deoxyglucose (a
Autor:
Masakazu Nitta, Hidesuke Yamamoto, Hiroshi Miwa, Akira Imamura, Masato Shikami, Akihito Hiramatsu, Norikazu Imai, Atsushi Satoh, Osami Daimaru, Hidetsugu Mihara
Publikováno v:
European Journal of Haematology. 71:130-132
We describe a patient who presented with aplastic anaemia associated with the Philadelphia (Ph1) chromosome during immunosuppressive therapy and who subsequently developed myelodysplastic syndrome (MDS) with monosomy 7. Initially the patient had hypo
Autor:
Masakazu Nitta, Hidetsugu Mihara, Hiroshi Miwa, Yoshiro Kato, Akira Imamura, Atsushi Sato, Emi Tajima, Akihito Hiramatsu, Minori Kanakura, Motohiro Wakabayashi
Publikováno v:
Nihon Naika Gakkai Zasshi. 91:1036-1038
22歳,男性.発熱出現,急性肝炎(A, B, C, D, G陰性)と診断され補液により肝機能改善. HSV, CMV, EBV,パルボウイルス,風疹,麻疹抗体価の上昇認めず. WBC 1,400/μl, Hb 12.1g/dl, Plt 22,000/μlと汎血球減少悪化
Autor:
Hidetsugu Mihara, Masafumi Taniwaki, Hidesuke Yamamoto, Mayuko Gotou, Kazuto Suganuma, Tomohiro Horio, Akihito Hiramatsu, Masato Shikami, Motohiro Wakabayashi, Masaya Watarai, Ichiro Hanamura, Hiroshi Miwa, Miyuki Takahashi, Tomohiko Taki, Shohei Mizuno, Norikazu Tsunekawa, Natsumi Sakamoto, Masakazu Nitta, Mineaki Goto, Hisao Nagoshi, Akira Imamura
Publikováno v:
Genes, chromosomescancer. 51(1)
In this study, we established and analyzed a novel human myeloid leukemia cell line, AMU-AML1, from a patient with acute myeloid leukemia with multilineage dysplasia before the initiation of chemotherapy. AMU-AML1 cells were positive for CD13, CD33,
Autor:
Akira Imamura, Hiroshi Miwa, Norikazu Imai, Hidetsugu Mihara, Masakazu Nitta, Mayuko Gotou, Kazuto Suganuma, Masato Shikami, Motohiro Wakabayashi, Mineaki Goto, Masaya Watarai, Ichiro Hanamura, Akihito Hiramatsu, Hidesuke Yamamoto, Miyuki Takahashi, Shohei Mizuno
Publikováno v:
Leukemialymphoma. 51(11)
For generation of energy, cancer cells utilize glycolysis more vigorously than oxidative phosphorylation in mitochondria (Warburg effect). We examined the energy metabolism of four leukemia cell lines by using glycolysis inhibitor, 2-deoxy-d-glucose